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Intensive Care Medicine

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01-07-2009 | Original

Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients

Authors: Janett Kreutziger, Volker Wenzel, Andrea Kurz, Mihai Adrian Constantinescu

Published in: Intensive Care Medicine | Issue 7/2009

Abstract

Purpose

The goal of this study was to analyse a possible association of admission blood glucose with hospital mortality of polytraumatised patients and to develop an outcome prediction model for this patient group.

Methods

The outcome of adult polytraumatised patients admitted to the University Hospital of Berne, Switzerland, between 2002 and 2004 with an ISS ≥ 17, and more than one severely injured organ system was retrospectively analysed.

Results

The inclusion criteria were met by 555 patients, of which 108 (19.5%) died. Hyperglycaemia proved to be an independent predictor for hospital mortality (P < 0.0001), following multiple regression analysis. After inclusion of admission blood glucose, the calculated mortality prediction model performed better than currently described models (P < 0.0001, AUC 0.924).

Conclusion

In this retrospective, single-centre study in polytraumatised patients, admission blood glucose proved to be an independent predictor of hospital mortality following regression analysis controlling for age, gender, injury severity and other laboratory parameters. A reliable admission blood glucose-based mortality prediction model for polytraumatised patients could be established. This observation may be helpful in improving the precision of future outcome prediction models for polytraumatised patients. These observations warrant further prospective evaluation.

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Title: Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients
Authors: Janett Kreutziger
Volker Wenzel
Andrea Kurz
Mihai Adrian Constantinescu
Publication date: 01-07-2009
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 7/2009
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1446-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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