Published in:
Open Access
01-08-2016 | General Gynecology
Adhesions and endometriosis: challenges in subfertility management
(An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group)
Authors:
R. L. De Wilde, J. Alvarez, H. Brölmann, R. Campo, Y. Cheong, P. Lundorff, L. Pawelczyk, H. Roman, A. di Spiezio Sardo, M. Wallwiener
Published in:
Archives of Gynecology and Obstetrics
|
Issue 2/2016
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Abstract
There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization.