Skip to main content
Top
Published in: Addiction Science & Clinical Practice 1/2021

Open Access 01-12-2021 | Methodology

Addressing complex pharmacy consultations: methods used to develop a person-centred intervention to highlight alcohol within pharmacist reviews of medications

Authors: Jim McCambridge, Karl Atkin, Ranjita Dhital, Brent Foster, Brendan Gough, Mary Madden, Stephanie Morris, Ronan O’Carroll, Margaret Ogden, Anne Van Dongen, Sue White, Cate Whittlesea, Duncan Stewart

Published in: Addiction Science & Clinical Practice | Issue 1/2021

Login to get access

Abstract

Background

Alcohol is challenging to discuss, and patients may be reluctant to disclose drinking partly because of concern about being judged. This report presents an overview of the development of a medications review intervention co-produced with the pharmacy profession and with patients, which breaks new ground by seeking to give appropriate attention to alcohol within these consultations.

Methods

This intervention was developed in a series of stages and refined through conceptual discussion, literature review, observational and interview studies, and consultations with advisory groups. In this study we reflect on this process, paying particular attention to the methods used, where lessons may inform innovations in other complex clinical consultations.

Results

Early work with patients and pharmacists infused the entire process with a heightened sense of the complexity of consultations in everyday practice, prompting careful deliberation on the implications for intervention development. This required the research team to be highly responsive to both co-production inputs and data gathered in formally conducted studies, and to be committed to working through the implications for intervention design. The intervention thus evolved significantly over time, with the greatest transformations resulting from patient and pharmacist co-design workshops in the second stage of the process, where pharmacists elaborated on the nature of the need for training in particular. The original research plans provided a helpful structure, and unanticipated issues for investigation emerged throughout the process. This underscored the need to engage dynamically with changing contexts and contents and to avoid rigid adherence to any early prescribed plan.

Conclusions

Alcohol interventions are complex and require careful developmental research. This can be a messy enterprise, which can nonetheless shed new insights into the challenges involved in optimising interventions, and how to meet them, if embraced with an attitude of openness to learning. We found that exposing our own research plans to scrutiny resulted in changes to the intervention design that gained the confidence of different stakeholders. Our understanding of the methods used, and their consequences, may be bounded by the person-centred nature of this particular intervention.
Literature
1.
go back to reference World Health Organization. Global status report on alcohol and health 2018. In. Geneva: World Health Organization; 2018. World Health Organization. Global status report on alcohol and health 2018. In. Geneva: World Health Organization; 2018.
3.
4.
go back to reference Towards a smokefree generation: a tobacco control plan for England. Towards a smokefree generation: a tobacco control plan for England.
6.
go back to reference Thom B, Tellez C. A difficult business: detecting and managing alcohol problems in general practice. Br J Addict. 1986;81(3):405–18.PubMedCrossRef Thom B, Tellez C. A difficult business: detecting and managing alcohol problems in general practice. Br J Addict. 1986;81(3):405–18.PubMedCrossRef
7.
go back to reference Kaner E, Rapley T, May C. Seeing through the glass darkly? A qualitative exploration of GPs’ drinking and their alcohol intervention practices. Fam Pract. 2006;23(4):481–7.PubMedCrossRef Kaner E, Rapley T, May C. Seeing through the glass darkly? A qualitative exploration of GPs’ drinking and their alcohol intervention practices. Fam Pract. 2006;23(4):481–7.PubMedCrossRef
8.
go back to reference McCambridge J, Saitz R. Rethinking brief interventions for alcohol in general practice. BMJ. 2017;356:j116.PubMedCrossRef McCambridge J, Saitz R. Rethinking brief interventions for alcohol in general practice. BMJ. 2017;356:j116.PubMedCrossRef
9.
go back to reference Royal College of Psychiatrists. Alcohol: our favourite drug. London: Tavistock; 1986. Royal College of Psychiatrists. Alcohol: our favourite drug. London: Tavistock; 1986.
10.
go back to reference Edwards G. Alcohol: The World’s Favourite Drug. London: Penguin Books; 2000. Edwards G. Alcohol: The World’s Favourite Drug. London: Penguin Books; 2000.
12.
go back to reference Room R. Addiction and personal responsibility as solutions to the contradictions of neoliberal consumerism. Crit Public Health. 2011;21(2):141–51.CrossRef Room R. Addiction and personal responsibility as solutions to the contradictions of neoliberal consumerism. Crit Public Health. 2011;21(2):141–51.CrossRef
13.
go back to reference Reith G. Gambling and the contradictions of consumption—a genealogy of the “Pathological” subject. Am Behav Sci. 2007;51(1):33–55.CrossRef Reith G. Gambling and the contradictions of consumption—a genealogy of the “Pathological” subject. Am Behav Sci. 2007;51(1):33–55.CrossRef
14.
go back to reference Reith G. Addictive consumption: capitalism, modernity and excess. Abingdon, Oxon: Routledge; 2019. Reith G. Addictive consumption: capitalism, modernity and excess. Abingdon, Oxon: Routledge; 2019.
15.
go back to reference McCambridge J, Kypri K, Miller P, Hawkins B, Hastings G. Be aware of Drinkaware. Addiction. 2014;109:519–24.PubMedCrossRef McCambridge J, Kypri K, Miller P, Hawkins B, Hastings G. Be aware of Drinkaware. Addiction. 2014;109:519–24.PubMedCrossRef
16.
go back to reference Moodie R, Stuckler D, Monteiro C, Sheron N, Neal B, Thamarangsi T, Lincoln P, Casswell S. Lancet NCDAG: Profits and pandemics: prevention of harmful effects of tobacco, alcohol, and ultra-processed food and drink industries. Lancet. 2013;381(9867):670–9.PubMedCrossRef Moodie R, Stuckler D, Monteiro C, Sheron N, Neal B, Thamarangsi T, Lincoln P, Casswell S. Lancet NCDAG: Profits and pandemics: prevention of harmful effects of tobacco, alcohol, and ultra-processed food and drink industries. Lancet. 2013;381(9867):670–9.PubMedCrossRef
17.
go back to reference Hastings G. The marketing matrix: how the corporation gets its power and how we can reclaim it. In. London: Routledge; 2013.CrossRef Hastings G. The marketing matrix: how the corporation gets its power and how we can reclaim it. In. London: Routledge; 2013.CrossRef
18.
go back to reference Madden M, McCambridge J. Alcohol marketing versus public health: David and Goliath? Glob Health. 2021;17(1):45.CrossRef Madden M, McCambridge J. Alcohol marketing versus public health: David and Goliath? Glob Health. 2021;17(1):45.CrossRef
19.
go back to reference Hastings G, Sheron N. Alcohol marketing: grooming the next generation: children are more exposed than adults and need much stronger protection. BMJ. 2013;346:f1227.PubMedCrossRef Hastings G, Sheron N. Alcohol marketing: grooming the next generation: children are more exposed than adults and need much stronger protection. BMJ. 2013;346:f1227.PubMedCrossRef
20.
go back to reference Lennox J, Emslie C, Sweeting H, Lyons A. The role of alcohol in constructing gender & class identities among young women in the age of social media. Int J Drug Policy. 2018;58:13–21.PubMedPubMedCentralCrossRef Lennox J, Emslie C, Sweeting H, Lyons A. The role of alcohol in constructing gender & class identities among young women in the age of social media. Int J Drug Policy. 2018;58:13–21.PubMedPubMedCentralCrossRef
21.
go back to reference Babor TF, Ritson EB, Hodgson RJ. Alcohol related problems in the primary health care setting: a review of early intervention strategies. Br J Addict. 1986;81:23–46.PubMedCrossRef Babor TF, Ritson EB, Hodgson RJ. Alcohol related problems in the primary health care setting: a review of early intervention strategies. Br J Addict. 1986;81:23–46.PubMedCrossRef
22.
go back to reference Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption - II. Addiction. 1993;88(6):791–804.PubMedCrossRef Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption - II. Addiction. 1993;88(6):791–804.PubMedCrossRef
23.
go back to reference WHO Brief Intervention Study Group. A cross-national trial of brief interventions with heavy drinkers. Am J Public Health. 1996;86(7):948–55.CrossRef WHO Brief Intervention Study Group. A cross-national trial of brief interventions with heavy drinkers. Am J Public Health. 1996;86(7):948–55.CrossRef
25.
go back to reference Rehm J, Anderson P, Manthey J, Shield KD, Struzzo P, Wojnar M, Gual A. Alcohol use disorders in primary health care: what do we know and where do we go? Alcohol Alcohol. 2015;51(4):422–7.PubMedCrossRef Rehm J, Anderson P, Manthey J, Shield KD, Struzzo P, Wojnar M, Gual A. Alcohol use disorders in primary health care: what do we know and where do we go? Alcohol Alcohol. 2015;51(4):422–7.PubMedCrossRef
26.
go back to reference Glass JE, Andreasson S, Bradley KA, Finn SW, Williams EC, Bakshi AS, Gual A, Heather N, Sainz MT, Benegal V, et al. Rethinking alcohol interventions in health care: a thematic meeting of the International Network on Brief Interventions for Alcohol & Other Drugs (INEBRIA). Addict Sci Clin Pract. 2017;12(1):14.PubMedPubMedCentralCrossRef Glass JE, Andreasson S, Bradley KA, Finn SW, Williams EC, Bakshi AS, Gual A, Heather N, Sainz MT, Benegal V, et al. Rethinking alcohol interventions in health care: a thematic meeting of the International Network on Brief Interventions for Alcohol & Other Drugs (INEBRIA). Addict Sci Clin Pract. 2017;12(1):14.PubMedPubMedCentralCrossRef
27.
go back to reference McCambridge J, Rollnick S. Should brief interventions in primary care address alcohol problems more strongly? Addiction. 2014;109(7):1054–8.PubMedCrossRef McCambridge J, Rollnick S. Should brief interventions in primary care address alcohol problems more strongly? Addiction. 2014;109(7):1054–8.PubMedCrossRef
28.
29.
go back to reference Andreasson SB. Tackling alcohol use: screening, target group, and patient centred care. BMJ. 2017;356:j1119.PubMedCrossRef Andreasson SB. Tackling alcohol use: screening, target group, and patient centred care. BMJ. 2017;356:j1119.PubMedCrossRef
30.
go back to reference Dhital R, Norman I, Whittlesea C, Murrells T, McCambridge J. The effectiveness of brief alcohol interventions delivered by community pharmacists: randomised controlled trial. Addiction. 2015;110(10):1586–94.PubMedPubMedCentralCrossRef Dhital R, Norman I, Whittlesea C, Murrells T, McCambridge J. The effectiveness of brief alcohol interventions delivered by community pharmacists: randomised controlled trial. Addiction. 2015;110(10):1586–94.PubMedPubMedCentralCrossRef
31.
go back to reference Quirk A, MacNeil V, Dhital R, Whittlesea C, Norman I, McCambridge J. Qualitative process study of community pharmacist brief alcohol intervention effectiveness trial: Can research participation effects explain a null finding? Drug Alcohol Depend. 2016;161:36–41.PubMedCrossRef Quirk A, MacNeil V, Dhital R, Whittlesea C, Norman I, McCambridge J. Qualitative process study of community pharmacist brief alcohol intervention effectiveness trial: Can research participation effects explain a null finding? Drug Alcohol Depend. 2016;161:36–41.PubMedCrossRef
32.
go back to reference Morris S, Madden M, Gough B, Atkin K, McCambridge J. Missing in action: Insights from an exploratory ethnographic observation study of alcohol in everyday UK community pharmacy practice. Drug Alcohol Rev. 2019;38(5):561–8.PubMedCrossRef Morris S, Madden M, Gough B, Atkin K, McCambridge J. Missing in action: Insights from an exploratory ethnographic observation study of alcohol in everyday UK community pharmacy practice. Drug Alcohol Rev. 2019;38(5):561–8.PubMedCrossRef
33.
go back to reference Stewart D, Hewitt C, McCambridge J. Exploratory validation study of the individual AUDIT-C items among older people. Alcohol Alcohol. 2020;56(3):258–65.CrossRef Stewart D, Hewitt C, McCambridge J. Exploratory validation study of the individual AUDIT-C items among older people. Alcohol Alcohol. 2020;56(3):258–65.CrossRef
34.
go back to reference Madden M, Morris S, Atkin K, Gough B, McCambridge J. Patient perspectives on discussing alcohol as part of medicines review in community pharmacies. Res Soc Admin Pharm. 2019;16(1):96–101.CrossRef Madden M, Morris S, Atkin K, Gough B, McCambridge J. Patient perspectives on discussing alcohol as part of medicines review in community pharmacies. Res Soc Admin Pharm. 2019;16(1):96–101.CrossRef
35.
go back to reference Stewart D, Whittlesea C, Dhital R, Newbould L, McCambridge J. Community pharmacist led medication reviews in the UK: A scoping review of the medicines use review and the new medicine service literatures. Res Soc Admin Pharm. 2020;16(2):111–22.CrossRef Stewart D, Whittlesea C, Dhital R, Newbould L, McCambridge J. Community pharmacist led medication reviews in the UK: A scoping review of the medicines use review and the new medicine service literatures. Res Soc Admin Pharm. 2020;16(2):111–22.CrossRef
36.
go back to reference Medical Research Council. A Framework for Development and Evaluation of RCTs for Complex Interventions to Improve Health In. London: MRC Health Services & Public Health Research Board; 2000. Medical Research Council. A Framework for Development and Evaluation of RCTs for Complex Interventions to Improve Health In. London: MRC Health Services & Public Health Research Board; 2000.
37.
38.
go back to reference Petticrew M. When are complex interventions “complex”? When are simple interventions “simple”? Eur J Public Health. 2011;21(4):397–8.PubMedCrossRef Petticrew M. When are complex interventions “complex”? When are simple interventions “simple”? Eur J Public Health. 2011;21(4):397–8.PubMedCrossRef
39.
go back to reference Leventhal H, Brissette I, Leventhal EA. The common-sense model of self-regulation of health and illness. In: Cameron LD, Leventhal H, editors. The Self-Regulation of Heatlh and Illness Behaviour. Abingdon: Routledge; 2003. Leventhal H, Brissette I, Leventhal EA. The common-sense model of self-regulation of health and illness. In: Cameron LD, Leventhal H, editors. The Self-Regulation of Heatlh and Illness Behaviour. Abingdon: Routledge; 2003.
40.
go back to reference Horne R, Chapman SC, Parham R, Freemantle N, Forbes A, Cooper V. Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. PLoS ONE. 2013;8(12):e80633.PubMedPubMedCentralCrossRef Horne R, Chapman SC, Parham R, Freemantle N, Forbes A, Cooper V. Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework. PLoS ONE. 2013;8(12):e80633.PubMedPubMedCentralCrossRef
41.
go back to reference Rousseau N, Turner KM, Duncan E, O’Cathain A, Croot L, Yardley L, Hoddinott P. Attending to design when developing complex health interventions: a qualitative interview study with intervention developers and associated stakeholders. PLoS ONE. 2019;14(10):e0223615.PubMedPubMedCentralCrossRef Rousseau N, Turner KM, Duncan E, O’Cathain A, Croot L, Yardley L, Hoddinott P. Attending to design when developing complex health interventions: a qualitative interview study with intervention developers and associated stakeholders. PLoS ONE. 2019;14(10):e0223615.PubMedPubMedCentralCrossRef
42.
go back to reference Gaume J, Grazioli VS, Paroz S, Fortini C, Bertholet N, Daeppen JB. Developing a brief motivational intervention for young adults admitted with alcohol intoxication in the emergency department - Results from an iterative qualitative design. PLoS ONE. 2021;16(2):e0246652.PubMedPubMedCentralCrossRef Gaume J, Grazioli VS, Paroz S, Fortini C, Bertholet N, Daeppen JB. Developing a brief motivational intervention for young adults admitted with alcohol intoxication in the emergency department - Results from an iterative qualitative design. PLoS ONE. 2021;16(2):e0246652.PubMedPubMedCentralCrossRef
43.
go back to reference Madden M, Morris S, Stewart D, Atkin K, Gough B, McCambridge J. Conceptualising alcohol consumption in relation to long-term health conditions: Exploring risk in interviewee accounts of drinking and taking medications. PLoS ONE. 2019;14(11):e0224706.PubMedPubMedCentralCrossRef Madden M, Morris S, Stewart D, Atkin K, Gough B, McCambridge J. Conceptualising alcohol consumption in relation to long-term health conditions: Exploring risk in interviewee accounts of drinking and taking medications. PLoS ONE. 2019;14(11):e0224706.PubMedPubMedCentralCrossRef
44.
go back to reference Gough B, Madden, M., Morris, S., Atkin, K., McCambridge, J.: How do older people normalise their drinking?: a discursive analysis of interviewee accounts. Appetite 2019 (in press). Gough B, Madden, M., Morris, S., Atkin, K., McCambridge, J.: How do older people normalise their drinking?: a discursive analysis of interviewee accounts. Appetite 2019 (in press).
45.
go back to reference Stewart D, Whittlesea C, Dhital R, Newbould L, McCambridge J. Community pharmacist led medication reviews in the UK: A scoping review of the medicines use review and the new medicine service literatures. Res Soc Admin Pharm. 2019;16(2):111–22.CrossRef Stewart D, Whittlesea C, Dhital R, Newbould L, McCambridge J. Community pharmacist led medication reviews in the UK: A scoping review of the medicines use review and the new medicine service literatures. Res Soc Admin Pharm. 2019;16(2):111–22.CrossRef
46.
go back to reference Madden M, Morris S, Ogden M, Lewis D, Stewart D, O’Carroll RE, McCambridge J. Introducing alcohol as a drug in medicine reviews with pharmacists: findings from a co-design workshop with patients. Drug Alcohol Rev. 2021;40(6):1028–36.PubMedCrossRef Madden M, Morris S, Ogden M, Lewis D, Stewart D, O’Carroll RE, McCambridge J. Introducing alcohol as a drug in medicine reviews with pharmacists: findings from a co-design workshop with patients. Drug Alcohol Rev. 2021;40(6):1028–36.PubMedCrossRef
47.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:1. Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:1.
48.
go back to reference Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37.PubMedPubMedCentralCrossRef Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37.PubMedPubMedCentralCrossRef
49.
go back to reference Stewart D, van Dongen A, Watson M, Mandefield L, Atkin K, Dhital R, Foster B, Gough B, Hewitt C, Madden M, et al. A pilot cluster randomised trial of the medicines and alcohol consultation (MAC): an intervention to discuss alcohol use in community pharmacy medicine review services. Bmc Health Serv Res. 2020;20(1):943.PubMedPubMedCentralCrossRef Stewart D, van Dongen A, Watson M, Mandefield L, Atkin K, Dhital R, Foster B, Gough B, Hewitt C, Madden M, et al. A pilot cluster randomised trial of the medicines and alcohol consultation (MAC): an intervention to discuss alcohol use in community pharmacy medicine review services. Bmc Health Serv Res. 2020;20(1):943.PubMedPubMedCentralCrossRef
50.
go back to reference Stewart D, Madden M, Van Dongen A, Watson M, Morris S, Whittlesea C, McCambridge J. Process study within a pilot cluster randomised trial in community pharmacy: an exploration of pharmacist readiness for research. Res Soc Admin Pharm. 2021;17(10):1750–7.CrossRef Stewart D, Madden M, Van Dongen A, Watson M, Morris S, Whittlesea C, McCambridge J. Process study within a pilot cluster randomised trial in community pharmacy: an exploration of pharmacist readiness for research. Res Soc Admin Pharm. 2021;17(10):1750–7.CrossRef
51.
go back to reference Madden M, Morris S, Ogden M, Lewis D, Stewart D, McCambridge J. Producing co-production: reflections on the development of a complex intervention. Health Expect. 2020;23(3):659–69.PubMedPubMedCentralCrossRef Madden M, Morris S, Ogden M, Lewis D, Stewart D, McCambridge J. Producing co-production: reflections on the development of a complex intervention. Health Expect. 2020;23(3):659–69.PubMedPubMedCentralCrossRef
52.
go back to reference Atkin K, Madden M, Morris S, Gough B, McCambridge J. Community pharmacy and public health: preserving professionalism by extending the pharmacy gaze? Sociol Health Illn. 2021;43(2):336–52.PubMedCrossRef Atkin K, Madden M, Morris S, Gough B, McCambridge J. Community pharmacy and public health: preserving professionalism by extending the pharmacy gaze? Sociol Health Illn. 2021;43(2):336–52.PubMedCrossRef
54.
go back to reference O’Cathain A, Croot L, Duncan E, Rousseau N, Sworn K, Turner KM, Yardley L, Hoddinott P. Guidance on how to develop complex interventions to improve health and healthcare. BMJ Open. 2019;9(8):e029954.PubMedPubMedCentralCrossRef O’Cathain A, Croot L, Duncan E, Rousseau N, Sworn K, Turner KM, Yardley L, Hoddinott P. Guidance on how to develop complex interventions to improve health and healthcare. BMJ Open. 2019;9(8):e029954.PubMedPubMedCentralCrossRef
55.
go back to reference Turner KM, Rousseau N, Croot L, Duncan E, Yardley L, O’Cathain A, Hoddinott P. Understanding successful development of complex health and healthcare interventions and its drivers from the perspective of developers and wider stakeholders: an international qualitative interview study. BMJ Open. 2019;9(5):e028756.PubMedPubMedCentralCrossRef Turner KM, Rousseau N, Croot L, Duncan E, Yardley L, O’Cathain A, Hoddinott P. Understanding successful development of complex health and healthcare interventions and its drivers from the perspective of developers and wider stakeholders: an international qualitative interview study. BMJ Open. 2019;9(5):e028756.PubMedPubMedCentralCrossRef
Metadata
Title
Addressing complex pharmacy consultations: methods used to develop a person-centred intervention to highlight alcohol within pharmacist reviews of medications
Authors
Jim McCambridge
Karl Atkin
Ranjita Dhital
Brent Foster
Brendan Gough
Mary Madden
Stephanie Morris
Ronan O’Carroll
Margaret Ogden
Anne Van Dongen
Sue White
Cate Whittlesea
Duncan Stewart
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Addiction Science & Clinical Practice / Issue 1/2021
Electronic ISSN: 1940-0640
DOI
https://doi.org/10.1186/s13722-021-00271-5

Other articles of this Issue 1/2021

Addiction Science & Clinical Practice 1/2021 Go to the issue