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BMC Pediatrics
Published in: BMC Pediatrics 1/2015

Open Access 01-12-2015 | Research article

Adding anthropometric measures of regional adiposity to BMI improves prediction of cardiometabolic, inflammatory and adipokines profiles in youths: a cross-sectional study

Authors: Hanen Samouda, Carine de Beaufort, Saverio Stranges, Benjamin C. Guinhouya, Georges Gilson, Marco Hirsch, Julien Jacobs, Sonia Leite, Michel Vaillant, Frédéric Dadoun

Published in: BMC Pediatrics | Issue 1/2015

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Abstract

Background

Paediatric research analysing the relationship between the easy-to-use anthropometric measures for adiposity and cardiometabolic risk factors remains highly controversial in youth. Several studies suggest that only body mass index (BMI), a measure of relative weight, constitutes an accurate predictor, whereas others highlight the potential role of waist-to-hip ratio (WHR), waist circumference (Waist C), and waist-to-height ratio (WHtR). In this study, we examined the effectiveness of adding anthropometric measures of body fat distribution (Waist C Z Score, WHR Z Score and/or WHtR) to BMI Z Score to predict cardiometabolic risk factors in overweight and obese youth. We also examined the consistency of these associations with the “total fat mass + trunk/legs fat mass” and/or the “total fat mass + trunk fat mass” combinations, as assessed by dual energy X-ray absorptiometry (DXA), the gold standard measurement of body composition.

Methods

Anthropometric and DXA measurements of total and regional adiposity, as well as a comprehensive assessment of cardiometabolic, inflammatory and adipokines profiles were performed in 203 overweight and obese 7–17 year-old youths from the Paediatrics Clinic, Centre Hospitalier de Luxembourg.

Results

Adding only one anthropometric surrogate of regional fat to BMI Z Score improved the prediction of insulin resistance (WHR Z Score, R2: 45.9 %. Waist C Z Score, R2: 45.5 %), HDL-cholesterol (WHR Z Score, R2: 9.6 %. Waist C Z Score, R2: 10.8 %. WHtR, R2: 6.5 %), triglycerides (WHR Z Score, R2: 11.7 %. Waist C Z Score, R2: 12.2 %), adiponectin (WHR Z Score, R2: 14.3 %. Waist C Z Score, R2: 17.7 %), CRP (WHR Z Score, R2: 18.2 %. WHtR, R2: 23.3 %), systolic (WHtR, R2: 22.4 %), diastolic blood pressure (WHtR, R2: 20 %) and fibrinogen (WHtR, R2: 21.8 %). Moreover, WHR Z Score, Waist C Z Score and/or WHtR showed an independent significant contribution according to these models. These results were in line with the DXA findings.

Conclusions

Adding anthropometric measures of regional adiposity to BMI Z Score improves the prediction of cardiometabolic, inflammatory and adipokines profiles in youth.
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Metadata
Title
Adding anthropometric measures of regional adiposity to BMI improves prediction of cardiometabolic, inflammatory and adipokines profiles in youths: a cross-sectional study
Authors
Hanen Samouda
Carine de Beaufort
Saverio Stranges
Benjamin C. Guinhouya
Georges Gilson
Marco Hirsch
Julien Jacobs
Sonia Leite
Michel Vaillant
Frédéric Dadoun
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2015
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-015-0486-5

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