Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
AIDS and Behavior
Published in: AIDS and Behavior 7/2014

01-07-2014 | Original Paper

Adapted Personalized Cognitive Counseling for Episodic Substance-Using Men Who Have Sex with Men: A Randomized Controlled Trial

Authors: Phillip O. Coffin, Glenn-Milo Santos, Grant Colfax, Moupali Das, Tim Matheson, Erin DeMicco, James Dilley, Eric Vittinghoff, Jerris L. Raiford, Monique Carry, Jeffrey H. Herbst

Published in: AIDS and Behavior | Issue 7/2014

Login to get access

Abstract

Episodic drug use and binge drinking are associated with HIV risk among substance-using men who have sex with men (SUMSM), yet no evidence-based interventions exist for these men. We adapted personalized cognitive counseling (PCC) to address self-justifications for high-risk sex among HIV-negative, episodic SUMSM, then randomized men to PCC (n = 162) with HIV testing or control (n = 164) with HIV testing alone. No significant between-group differences were found in the three primary study outcomes: number of unprotected anal intercourse events (UAI), number of UAI partners, and UAI with three most recent non-primary partners. In a planned subgroup analysis of non-substance dependent men, there were significant reductions in UAI with most recent non-primary partners among PCC participants (RR = 0.56; 95 %CI 0.34–0.92; P = 0.02). We did not find evidence that PCC reduced sexual risk behaviors overall, but observed significant reductions in UAI events among non-dependent SUMSM. PCC may be beneficial among SUMSM screening negative for substance dependence.
Literature
1.
Purcell DW, Johnson C, Lansky A, Prejean J, Stein R, Denning P, et al. Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates. Open AIDS J. 2012;6:98–107.PubMedCentralPubMedCrossRef
2.
3.
4.
Centers for Disease Control and Prevention. Diagnoses of HIV infection and AIDS in the United States and dependent areas, 2011. HIV Surveillance Report. 2013;23.
5.
Finlayson TJ, Le B, Smith A, Bowles K, Cribbin M, Miles I, et al. HIV risk, prevention, and testing behaviors among men who have sex with men—National HIV Behavioral Surveillance System, 21 U.S. cities, United States, 2008. MMWR Surveill Summ. 2011;60(14):1–34.PubMed
6.
Centers for Disease Control and Prevention. Vital signs: binge drinking prevalence, frequency, and intensity among adults—United States, 2010. MMWR Morb Mortal Wkly Rep. 2012;61(1):14–6.
7.
Irwin TW, Morgenstern J. Drug-use patterns among men who have sex with men presenting for alcohol treatment: differences in ethnic and sexual identity. J Urban Health. 2005;82(Suppl 1):i127–33.PubMedCentralPubMedCrossRef
8.
Stall R, Wiley J. A comparison of alcohol and drug use patterns of homosexual and heterosexual men: the San Francisco Men’s Health Study. Drug Alcohol Depend. 1988;22(1–2):63–73.PubMedCrossRef
9.
Drumright LN, Little SJ, Strathdee SA, Slymen DJ, Araneta MR, Malcarne VL, et al. Unprotected anal intercourse and substance use among men who have sex with men with recent HIV infection. J Acquir Immune Defic Syndr. 2006;43(3):344–50.PubMedCrossRef
10.
Colfax G, Coates TJ, Husnik MJ, Huang Y, Buchbinder S, Koblin B, et al. Longitudinal patterns of methamphetamine, popper (amyl nitrite), and cocaine use and high-risk sexual behavior among a cohort of San Francisco men who have sex with men. J Urban Health. 2005;82(1 Suppl 1):i62–70.PubMedCentralPubMedCrossRef
11.
Colfax G, Vittinghoff E, Husnik MJ, McKirnan D, Buchbinder S, Koblin B, et al. Substance use and sexual risk: a participant- and episode-level analysis among a cohort of men who have sex with men. Am J Epidemiol. 2004;159(10):1002–12.PubMedCrossRef
12.
Colfax GN, Mansergh G, Guzman R, Vittinghoff E, Marks G, Rader M, et al. Drug use and sexual risk behavior among gay and bisexual men who attend circuit parties: a venue-based comparison. J Acquir Immune Defic Syndr. 2001;28(4):373–9.PubMedCrossRef
13.
Celentano DD, Valleroy LA, Sifakis F, MacKellar DA, Hylton J, Thiede H, et al. Associations between substance use and sexual risk among very young men who have sex with men. Sex Transm Dis. 2006;33(4):265–71.PubMed
14.
Wong W, Chaw JK, Kent CK, Klausner JD. Risk factors for early syphilis among gay and bisexual men seen in an STD clinic: San Francisco, 2002–2003. Sex Transm Dis. 2005;32(7):458–63.PubMedCrossRef
15.
Buchacz K, McFarland W, Kellogg TA, Loeb L, Holmberg SD, Dilley J, et al. Amphetamine use is associated with increased HIV incidence among men who have sex with men in San Francisco. AIDS. 2005;19(13):1423–4.PubMedCrossRef
16.
Hirshfield S, Remien RH, Humberstone M, Walavalkar I, Chiasson MA. Substance use and high-risk sex among men who have sex with men: a national online study in the USA. AIDS Care. 2004;16(8):1036–47.PubMedCrossRef
17.
Vanable PA, McKirnan DJ, Buchbinder SP, Bartholow BN, Douglas JM Jr, Judson FN, et al. Alcohol use and high-risk sexual behavior among men who have sex with men: the effects of consumption level and partner type. Health Psychol. 2004;23(5):525–32.PubMedCrossRef
18.
Seage GR 3rd, Mayer KH, Horsburgh CR Jr, Holmberg SD, Moon MW, Lamb GA. The relation between nitrite inhalants, unprotected receptive anal intercourse, and the risk of human immunodeficiency virus infection. Am J Epidemiol. 1992;135(1):1–11.PubMed
19.
Buchbinder SP, Vittinghoff E, Heagerty PJ, Celum CL, Seage GR 3rd, Judson FN, et al. Sexual risk, nitrite inhalant use, and lack of circumcision associated with HIV seroconversion in men who have sex with men in the United States. J Acquir Immune Defic Syndr. 2005;39(1):82–9.PubMedCrossRef
20.
Reback CJ, Larkins S, Shoptaw S. Changes in the meaning of sexual risk behaviors among gay and bisexual male methamphetamine abusers before and after drug treatment. AIDS Behav. 2004;8(1):87–98.PubMedCrossRef
21.
Semple SJ, Patterson TL, Grant I. Motivations associated with methamphetamine use among HIV+ men who have sex with men. J Subst Abuse Treat. 2002;22(3):149–56.PubMedCrossRef
22.
Drumright LN, Patterson TL, Strathdee SA. Club drugs as causal risk factors for HIV acquisition among men who have sex with men: a review. Subst Use Misuse. 2006;41(10–12):1551–601.PubMedCrossRef
23.
McKirnan DJ, Vanable PA, Ostrow DG, Hope B. Expectancies of sexual “escape” and sexual risk among drug and alcohol-involved gay and bisexual men. J Subst Abuse. 2001;13(1–2):137–54.PubMedCrossRef
24.
Diaz RM, Heckert AL, Sanchez J. Reasons for stimulant use among Latino gay men in San Francisco: a comparison between methamphetamine and cocaine users. J Urban Health. 2005;82(1 Suppl 1):i71–8.PubMedCentralPubMedCrossRef
25.
Santos GM, Coffin PO, Das M, Matheson T, DeMicco E, Raiford JL, et al. Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco. J Acquir Immune Defic Syndr. 2013;63(4):540–4. doi:10.​1097/​QAI.​0b013e318293f10b​.
26.
Raymond H. Personal Communication. San Francisco Department of Public Health. March 21, 2007.
27.
Bingham T. Personal Communication. County of Los Angeles Department of Public Health. March 18, 2007.
28.
Sifakis F. Personal Communication. Johns Hopkins Bloomberg School of Public Health. March 16, 2007.
29.
Prachand N. Personal Communication. Chicago Department of Public Health. March 15, 2007.
30.
San Francisco AIDS Office. HIV/AIDS epidemiology annual report. San Francisco: San Francisco Department of Public Health; 2005.
31.
Shoptaw S, Reback CJ, Frosch DL, Rawson RA. Stimulant abuse treatment as HIV prevention. J Addict Dis. 1998;17(4):19–32.PubMedCrossRef
32.
Kalichman SC, Weinhardt L, DiFonzo K, Austin J, Luke W. Sensation seeking and alcohol use as markers of sexual transmission risk behavior in HIV-positive men. Ann Behav Med. 2002;24(3):229–35.PubMedCrossRef
33.
Parsons JT, Vicioso KJ, Punzalan JC, Halkitis PN, Kutnick A, Velasquez MM. The impact of alcohol use on the sexual scripts of HIV-positive men who have sex with men. J Sex Res. 2004;41(2):160–72.PubMedCentralPubMedCrossRef
34.
35.
Centers for Disease Control and Prevention. PS07-004: Adopting and demonstrating the adaptation of prevention techniques for persons at highest risk of acquiring or transmitting human immunodeficiency virus (ADAPT 2)—(UR6). Atlanta: Centers for Disease Control and Prevention; 2007.
36.
Lyles CM, Kay LS, Crepaz N, Herbst JH, Passin WF, Kim AS, et al. Best-evidence interventions: findings from a systematic review of HIV behavioral interventions for US populations at high risk, 2000–2004. Am J Public Health. 2007;97(1):133–43.PubMedCentralPubMedCrossRef
37.
Dilley JW, Woods WJ, Sabatino J, Lihatsh T, Adler B, Casey S, et al. Changing sexual behavior among gay male repeat testers for HIV: a randomized, controlled trial of a single-session intervention. J Acquir Immune Defic Syndr. 2002;30(2):177–86.PubMedCrossRef
38.
Dilley JW, Woods WJ, Loeb L, Nelson K, Sheon N, Mullan J, et al. Brief cognitive counseling with HIV testing to reduce sexual risk among men who have sex with men: results from a randomized controlled trial using paraprofessional counselors. J Acquir Immune Defic Syndr. 2007;44(5):569–77.PubMedCrossRef
39.
Dilley JW, Schwarcz S, Murphy J, Joseph C, Vittinghoff E, Scheer S. Efficacy of personalized cognitive counseling in men of color who have sex with men: secondary data analysis from a controlled intervention trial. AIDS Behav. 2011;15(5):970–5.PubMedCentralPubMedCrossRef
40.
Knight KR, Das M, Demicco E, Raiford JL, Matheson T, Shook A, et al. A roadmap for adapting an evidence-based HIV prevention intervention: Personal Cognitive Counseling (PCC) for episodic substance-using men who have sex with men. Prev Sci. 2013. doi:10.​1007/​s11121-013-0364-z.
41.
Mansergh G, Koblin BA, McKirnan DJ, Hudson SM, Flores SA, Weigand RE, et al. An intervention to reduce HIV risk behavior of substance-using men who have sex with men: a two-group randomized trial with a nonrandomized third group. PLoS Med. 2010;7(8):e1000329.PubMedCentralPubMedCrossRef
42.
Metzger DS, Koblin B, Turner C, Navaline H, Valenti F, Holte S, et al. Randomized controlled trial of audio computer-assisted self-interviewing: utility and acceptability in longitudinal studies. HIVNET Vaccine Preparedness Study Protocol Team. Am J Epidemiol. 2000;152(2):99–106.PubMedCrossRef
43.
44.
Bandura A. Social learning theory. Englewood Cliffs: Prentice Hall; 1977.
45.
Bandura A. Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev. 1977;84:191–215.PubMedCrossRef
46.
DiClemente CC, Prochaska JO. Processes and stages of self-change: coping and competence in smoking behavior change. In: Shiffman S, Wills TA, editors. Coping and substance abuse. San Diego: Academic Press; 1985.
47.
DiClemente CC, Prochaska JO, Gilbertini M. Self-efficacy and the stages of self change in smoking. Cogn Ther Res. 1985;9:181–200.CrossRef
48.
Gold RS, Skinner MJ. Situational factors and thought processes associated with unprotected intercourse in young gay men. AIDS. 1992;6(9):1021–30.PubMedCrossRef
49.
Gossop M, Darke S, Griffiths P, Hando J, Powis B, Hall W, et al. The severity of dependence scale (SDS): psychometric properties of the SDS in English and Australian samples of heroin, cocaine and amphetamine users. Addiction. 1995;90(5):607–14.PubMedCrossRef
50.
Topp L, Mattick RP. Choosing a cut-off on the severity of dependence scale (SDS) for amphetamine users. Addiction. 1997;92(7):839–45.PubMedCrossRef
51.
Lawrinson P, Copeland J, Gerber S, Gilmour S. Determining a cut-off on the severity of dependence scale (SDS) for alcohol dependence. Addict Behav. 2007;32(7):1474–9 Epub 2006/11/04.PubMedCrossRef
52.
Kaye S, Darke S. Determining a diagnostic cut-off on the severity of dependence scale (SDS) for cocaine dependence. Addiction. 2002;97(6):727–31.PubMedCrossRef
53.
Herbst JH, Beeker C, Matthew A, McNally T, Passin WF, Kay LS, et al. The effectiveness of individual-, group-, and community-level HIV behavioral risk-reduction interventions for adult men who have sex with men: a systematic review. Am J Prev Med. 2007;32:S38–67.PubMedCrossRef
54.
Wilton L, Herbst JH, Coury-Doniger P, Painter TM, English G, Alvarez ME, et al. Efficacy of an HIV/STI prevention intervention for black men who have sex with men: findings from the Many Men, Many Voices (3MV) project. AIDS Behav. 2009;13:532–44.PubMedCrossRef
55.
Safren SA, Blashill AJ, O’Cleirigh CM. Promoting the sexual health of MSM in the context of comorbid mental health problems. AIDS Behav. 2011;15(Suppl 1):S30–4.PubMedCentralPubMedCrossRef
56.
Morgenstern J, Bux DA Jr, Parsons J, Hagman BT, Wainberg M, Irwin T. Randomized trial to reduce club drug use and HIV risk behaviors among men who have sex with men. J Consult Clin Psychol. 2009;77(4):645–56.PubMedCentralPubMedCrossRef
57.
Shoptaw S, Reback CJ, Peck JA, Yang X, Rotheram-Fuller E, Larkins S, et al. Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual men. Drug Alcohol Depend. 2005;78(2):125–34.PubMedCrossRef
58.
Shoptaw S, Reback CJ, Larkins S, Wang PC, Rotheram-Fuller E, Dang J, et al. Outcomes using two tailored behavioral treatments for substance abuse in urban gay and bisexual men. J Subst Abuse Treat. 2008;35(3):285–93.PubMedCrossRef
59.
Mausbach BT, Semple SJ, Strathdee SA, Zians J, Patterson TL. Efficacy of a behavioral intervention for increasing safer sex behaviors in HIV-positive MSM methamphetamine users: results from the EDGE study. Drug Alcohol Depend. 2007;87(2–3):249–57.PubMedCentralPubMedCrossRef
60.
Colfax GN, Santos GM, Das M, Santos DM, Matheson T, Gasper J, et al. Mirtazapine to reduce methamphetamine use: a randomized controlled trial. Arch Gen Psychiatry. 2011;68(11):1168–75.PubMedCentralPubMedCrossRef
Metadata
Title
Adapted Personalized Cognitive Counseling for Episodic Substance-Using Men Who Have Sex with Men: A Randomized Controlled Trial
Authors
Phillip O. Coffin
Glenn-Milo Santos
Grant Colfax
Moupali Das
Tim Matheson
Erin DeMicco
James Dilley
Eric Vittinghoff
Jerris L. Raiford
Monique Carry
Jeffrey H. Herbst
Publication date
01-07-2014
Publisher
Springer US
Published in
AIDS and Behavior / Issue 7/2014
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-014-0712-4

Other articles of this Issue 7/2014

AIDS and Behavior 7/2014 Go to the issue

Original Paper

Current Cigarette Smoking Among HIV-Positive Current and Former Drug Users: Associations with Individual and Social Characteristics

Original Paper

Evidence of a Syndemic Among Young Canadian Gay and Bisexual Men: Uncovering the Associations Between Anti-gay Experiences, Psychosocial Issues, and HIV Risk

Brief Report

Whoonga and the Abuse and Diversion of Antiretrovirals in Soweto, South Africa

Original Paper

Drinking Motives Among HIV Primary Care Patients

Original Paper

Opioid Analgesic Misuse is Associated with Incomplete Antiretroviral Adherence in a Cohort of HIV-Infected Indigent Adults in San Francisco

Brief Report

Association Between Alcohol Use and Sexually Transmitted Infection Incidence Among Kenyan Women Engaged in Transactional Sex
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Image Credits