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Critical Care
Published in: Critical Care 1/2022

01-12-2022 | Acute Respiratory Distress-Syndrome | Comment

Prone position during venovenous extracorporeal membrane oxygenation: survival analysis needed for a time-dependent intervention

Authors: Akram M. Zaaqoq, Adrian G. Barnett, Silver Heinsar, Matthew J. Griffee, Graeme MacLaren, Jeffrey P. Jacobs, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, Heidi J. Dalton, Giles J. Peek, the COVID-19 Critical Care Consortium (COVID Critical)

Published in: Critical Care | Issue 1/2022

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Excerpt

We read with great interest the paper of Giani and colleagues titled "Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis" published in the critical care journal [1]. We are surprised that their meta-analysis failed to show a survival benefit for prone positioning during venovenous extracorporeal membrane oxygenation (VV ECMO). We would like to postulate that this was due to the limitation of the statistical methods. …
Literature
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Giani M, Rezoagli E, Guervilly C, Rilinger J, Duburcq T, Petit M, Textoris L, Garcia B, Wengenmayer T, Grasselli G, et al. Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis. Crit Care (Lond, Engl). 2022;26(1):8.CrossRef
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Guérin C, Reignier J, Richard J-C, Beuret P, Gacouin A, Boulain T, Mercier E, Badet M, Mercat A, Baudin O, et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med. 2013;368(23):2159–68.CrossRef
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Guérin C, Beuret P, Constantin JM, Bellani G, Garcia-Olivares P, Roca O, Meertens JH, Maia PA, Becher T, Peterson J, et al. A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study. Intensive Care Med. 2018;44(1):22–37.CrossRef
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Garcia B, Cousin N, Bourel C, Jourdain M, Poissy J, Duburcq T. Prone positioning under VV-ECMO in SARS-CoV-2-induced acute respiratory distress syndrome. Crit Care (Lond, Engl). 2020;24(1):428.CrossRef
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Zaaqoq AM, Barnett AG, Griffee MJ, MacLaren G, Jacobs JP, Heinsar S, Suen JY, Bassi GL, Fraser JF, Dalton HJ et al. Beneficial effect of prone positioning during venovenous extracorporeal membrane oxygenation for coronavirus disease 2019. Crit Care Med. 2021.
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Papazian L, Schmidt M, Hajage D, Combes A, Petit M, Lebreton G, Rilinger J, Giani M, Le Breton C, Duburcq T et al. Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis. Intensive Care Med. 2022.
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Metadata
Title
Prone position during venovenous extracorporeal membrane oxygenation: survival analysis needed for a time-dependent intervention
Authors
Akram M. Zaaqoq
Adrian G. Barnett
Silver Heinsar
Matthew J. Griffee
Graeme MacLaren
Jeffrey P. Jacobs
Jacky Y. Suen
Gianluigi Li Bassi
John F. Fraser
Heidi J. Dalton
Giles J. Peek
the COVID-19 Critical Care Consortium (COVID Critical)
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2022
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-022-03923-3

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