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30-01-2022 | Acute Kidney Injury | Original Paper

Can microalbuminuria be an ındicator of renal ınvolvement in pediatric Covid 19 patients?

Authors: Sare Gülfem Özlü, Zehra Aydın, Berrak Naz Bozelli, Begüm Avcı, Mihriban İnözü, Fatma Şemsa Çaycı, Belgin Gülhan, Sevilay Sezer, Umut Selda Bayrakçı

Published in: Infection | Issue 3/2022

Abstract

Background

Proteinuria (both tubular and glomerular in origin) and its implications are well-known features of adult patients with COVID19. However currently studies addressing proteinuria and its role in the outcome of kidney and patients of pediatric COVID 19 is scarce. We aimed to evaluate the presence of microalbuminuria in order to detect early renal involvement in pediatric COVID 19 patients.

Methods

We prospectively evaluated 100 pediatric patients hospitalized with COVID 19 between April and July 2020. Clinical presentations, laboratory findings and outcomes were investigated. Microalbuminuria was compared with the age, gender, disease severity, and hemoglobin, platelet, leukocyte count and serum CRP levels of the patients.

Results

Twenty seven out of 100 patients had microalbuminuria. Fourteen patients had mild and fourteen had moderate disease. There was not any significant relation according to age and gender. Microalbuminuria was not related to the severity of the disease. Also the mean microalbuminuria level did not differ according to the disease course. Hemoglobin, platelet, leukocyte counts and serum CRP levels were also were not correlated with microalbuminuria levels.

Conclusion

Although there was no difference between the groups with different disease course; microalbuminuria is detected in an important ratio of pediatric patients with COVID 19 in this study. In the highlight of our findings we suggest that urinary findings of pediatric COVID patients should be carefully evaluated.

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Title: Can microalbuminuria be an ındicator of renal ınvolvement in pediatric Covid 19 patients?
Authors: Sare Gülfem Özlü
Zehra Aydın
Berrak Naz Bozelli
Begüm Avcı
Mihriban İnözü
Fatma Şemsa Çaycı
Belgin Gülhan
Sevilay Sezer
Umut Selda Bayrakçı
Publication date: 30-01-2022
Publisher: Springer Berlin Heidelberg
Keywords: Acute Kidney Injury
SARS-CoV-2
Hematuria
COVID-19
Microalbuminuria
Acute Kidney Injury
Published in: Infection / Issue 3/2022
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-021-01745-z

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