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Critical Care
Published in: Critical Care 1/2004

01-02-2004 | Poster presentation

Acute hyperglycemia impairs platelet receptor expression but not platelet aggregation in vitro

Authors: T Schuerholz, O Keil, L Friedrich, H Elsner, D Scheinichen

Published in: Critical Care | Special Issue 1/2004

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Excerpt

Elevated blood glucose concentration is an important factor for mortality and morbidity in critically ill patients. Previously, a randomized controlled trial showed that a blood glucose level of about 6 mmol/l is associated with less multiorgan failure and a significantly higher survival rate compared with levels above 8 mmol/l. Platelets play a crucial role in hemostasis and inflammation. However, the effect of short-term elevated blood glucose levels on platelet activation has not yet been evaluated systematically. …
Metadata
Title
Acute hyperglycemia impairs platelet receptor expression but not platelet aggregation in vitro
Authors
T Schuerholz
O Keil
L Friedrich
H Elsner
D Scheinichen
Publication date
01-02-2004
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2004
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc2719

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