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Trials
Published in: Trials 1/2020

01-12-2020 | Acupuncture | Research

The effect of TEAS on the quality of early recovery in patients undergoing gynecological laparoscopic surgery: a prospective, randomized, placebo-controlled trial

Authors: Xiangdi Yu, Fangxiang Zhang, Bingning Chen

Published in: Trials | Issue 1/2020

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Abstract

Introduction

In current study we assessed the effect of transcutaneous electrical acupoint stimulation (TEAS) on the quality of early recovery in patients undergoing gynecological laparoscopic surgery.

Methods

Sixty patients undergoing gynecological laparoscopic surgery were randomly assigned to TEAS (TEAS group) or control group (Con group). TEAS consisted of 30 min of stimulation (12–15 mA, 2/100 Hz) at the acupoints of Baihui (GV20), Yingtang (EX-HN-3), Zusanli (ST36) and Neiguan (PC6) before anesthesia. The patients in the Con group had the electrodes applied, but received no stimulation. Quality of recovery was assessed using a 40-item questionnaire as a measure of quality of recovery (QoR-40; maximum score 200) scoring system performed on preoperative day 1 (T0), postoperative day 1 (T1) and postoperative day 2 (T2); 100-mm visual analogue scale (VAS) scores at rest, mini-mental state examination (MMSE) scores, the incidence of nausea and vomiting, postoperative pain medications, and antiemetics were also recorded. Results: QoR-40 and MMSE scores of T0 showed no difference between two groups (QoR-40: 197.50 ± 2.57 vs. 195.83 ± 5.17), (MMSE: 26.83 ± 2.74 vs. 27.53 ± 2.88). Compared with the Con group, QoR-40 and MMSE scores of T1 and T2 were higher in the TEAS group (P < 0.05) (QoR-40: T1, 166.07 ± 8.44 vs. 175.33 ± 9.66; T2, 187.73 ± 5.47 vs. 191.40 ± 5.74), (MMSE: T1, 24.60 ± 2.35 vs. 26.10 ± 2.78; T2, 26.53 ± 2.94 vs. 27.83 ± 2.73). VAS scores of T1 and T2 were lower (P < 0.05) in the TEAS group (T1, 4.73 ± 1.53 vs. 3.70 ± 1.41; T2, 2.30 ± 0.95 vs. 1.83 ± 0.88); the incidence of postoperative nausea and vomiting (PONV), remedial antiemetics and remedial analgesia was lower in the TEAS group (P < 0.05) (PONV: 56.7% vs. 23.3%; incidence of remedial antiemetics: 53.3% vs. 23.3%; incidence of remedial analgesia: 80% vs. 43.3%).

Conclusion

The use of TEAS significantly promoted the quality of early recovery, improved MMSE scores and reduced the incidence of pain, nausea and vomiting in patients undergoing gynecological laparoscopic surgery.

Trial registration

ClinicalTrials.gov, NCT02619578. Registered on 2 December 2015.
Literature
1.
Chapron C, Fauconnier A, Goffinet F, Bréart G, Dubuisson JB. Laparoscopic surgery is not inherently dangerous for patients presenting with benign gynaecologic pathology. Results of a meta-analysis. Hum Reprod. 2002;17:1334–42.CrossRef
2.
Nieboer TE, Johnson N, Lethaby A, Tavender E, Curr E, Garry R, et al. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database Syst Rev. 2009;(3):CD003677.
3.
Medeiros LR, Stein AT, Fachel J, Garry R, Furness S. Laparoscopy versus laparotomy for benign ovarian tumor: a systematic review and meta-analysis. Int J Gynecol Cancer. 2008;18:387–99.CrossRef
4.
Zhou C, Gong Z, Hu S. Influence of carbon dioxide pneumoperitoneum in laparoscopic cholecystectomy on respiration and circulation of middle-aged and elderly patients. China J Endosc. 2005;11:657–9.
5.
Henny CP, Hofland J. Laparoscopic surgery: pitfalls due to anesthesia, positioning and pneumoperitoneum. Surg Endosc. 2005;19:1163–71.CrossRef
6.
Wang H, Xie Y, Zhang Q, et al. Transcutaneous electric acupoint stimulation reduces intra-operative remifentanil consumption and alleviates postoperative side-effects in patients undergoing sinusotomy: a prospective, randomized, placebo-controlled trial. Br J Anaesth. 2014;112:1075–82.CrossRef
7.
Wetzel B, Pavlovic D, Kuse R, et al. The effect of auricular acupuncture on fentanyl requirement during hip arthroplasty: a randomized controlled trial. Clin J Pain. 2011;27:262–7.CrossRef
8.
Arnberger M, Stadelmann K, Alischer P, et al. Monitoring of neuromuscular blockade at the P6 acupuncture point reduces the incidence of postoperative nausea and vomiting. Anesthesiology. 2007;107:903–8.CrossRef
9.
Ni X, Xie Y, Wang Q, et al. Cardioprotective effect of transcutaneous electric acupoint stimulation in the pediatric cardiac patients: a randomized controlled clinical trial. Paediatr Anaesth. 2012;22:805–11.CrossRef
10.
Myles PS, Weitkamp B, Jones K, et al. Validity and reliability of a postoperative quality of recovery score: the QoR-40. Br J Anaesth. 2000;84:11–5.CrossRef
11.
Myles PS, Reeves MD, Anderson H, et al. Measurement of quality of recovery in 5672 patients after anaesthesia and surgery. Anaesth Intensive Care. 2000;28:276–80.CrossRef
12.
De Oliveira GS Jr, Ahmad S, Fitzgerald PC, et al. Dose ranging study on the effect of preoperative dexamethasone on postoperative quality of recovery and opioid consumption after ambulatory gynaecological surgery. Br J Anaesth. 2011;107:362–71.CrossRef
13.
Myles PS, Williams DL, Hendrata M, et al. Patient satisfaction after anaesthesia and surgery: results of a prospective survey of 10,811 patients. Br J Anaesth. 2000;84:6–10.CrossRef
14.
Wu CL, Richman JM. Postoperative pain and quality of recovery. Curr Opin Anaesthesiol. 2004;17:455–60.CrossRef
15.
Dorans N, Kulick E. Differential item functioning on the mini-mental state examination: an application of the Mantel-Haenszel and standardization procedures. Med Care. 2006;44(Suppl 3):S107–14.CrossRef
16.
Kindler CH, Harms C, Amsler F, et al. The visual analog scale allows effective measurement of preoperative anxiety and detection of patients’ anesthetic concerns. Anesth Analg. 2000;90:706–12.CrossRef
17.
Gallagher EJ, Bijur PE, Latimer C, et al. Reliability and validity of a visual analog scale for acute abdominal pain in the ED. Am J Emerg Med. 2002;20:287–90.CrossRef
18.
Andersson LE, Baath M, Thorne A, Aspelin P, Odeberg-Wernerman S. Effect of carbon dioxide pneumoperitoneum on development of atelectasis during anesthesia, examined by spiral computed tomography. Anesthesiology. 2005;102:293–9.CrossRef
19.
Wu CL, Berenholtz SM, Pronovost PJ, Fleisher LA. Systematic review and analysis of post discharge symptoms after outpatient surgery. Anestheslology. 2002;96:994–1003.CrossRef
20.
Kotani N, Hashimoto H, Sato Y, et al. Preoperative intradermal acupuncture reduces postoperative pain, nausea and vomiting, analgesic requirement, and sympathoadrenal responses. Anesthesiology. 2001;95:349–5.CrossRef
21.
Sun Y, Gan TJ, Dubose JW, Habib AS. Acupuncture and related techniques for postoperative pain: a systematic review of randomized controlled trials. Br J Anaesth. 2008;101:151–60.CrossRef
22.
Shufang F. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neurosci Lett. 2010;478:150–5.CrossRef
23.
Kang JM. Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model. Brain Res. 2007;1131:211–9.CrossRef
24.
Liu L, Hoang-Gia T, Wu H, Lee MR, Gu L, Wang C, Yun BS, Wang Q, Ye S, Sung CK. Ginsenoside Rb1 improves spatial learning and memory by regulation of cell genesis in the hippocampal subregions of rats. Brain Res. 2011;1382:147–54.CrossRef
25.
Zhang Z, Wang C, Li Q, Zhang M, Zhao H, Dong L, Wang G, Jin Y. Electroacupuncture at ST36 accelerates the recovery of gastrointestinal motility after colorectal surgery: a randomized controlled trial. Acupunct Med. 2014;32(3):223–6.CrossRef
26.
Lu F, Zhu HM, Xie JJ, et al. Effects of electroacupuncture on behavior, plasma COR and expression of PKA and PKC in hippocampus of depression model rat. Zhonghuo Zhen Jiu. 2008;28:214–8.
27.
Chen HD, Jin LQ, Lou R. Effects of electroacupuncture on Baihui (GV20) for hypothalamic-pituitary-adrenal axis of chronic mild stress depression model rat. J Zhejiang Univ Tradit Chin Med. 2010;34:252–3.
28.
Shi RX, Wu Q, Qin LN, et al. The effect of eletroacupuncture at “Baihui”, “Yingtang” on weight and HPA axis of depression rats. J Clin Acupunct Moxib. 2007;23:50–3.
29.
Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008;9(1):46–56.CrossRef
30.
Yuan S, Zhang X, Bo Y, Li W, Zhang H, Jiang Q. The effects of electroacupuncture treatment on the postoperative cognitive function in aged rats with acute myocardial ischemia-reperfusion. Brain Res. 2014;17: 1593:19–29.CrossRef
31.
Tracey KJ. Physiology and immunology of the cholinergic anti-inflammatory pathway. J Clin Investig. 2007;117:289–96.CrossRef
32.
Das UN. Vagus nerve stimulation, depression and inflammation. Neuropsychopharmacology. 2007;32:2053–4.CrossRef
33.
Ulett GA, Han S, Han JS. Electroacupuncture: mechanisms and clinical application. Biol Psychiatry. 1998;44:129–38.CrossRef
34.
Han JS. Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies. Trends Neurosci. 2003;26:17–22.CrossRef
35.
Han JS, Chen XH, Sun SL, Xu XJ, Yuan Y, Yan SC, Hao JX, Terenius L. Effect of low- and high-frequency TENS on Metenkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF. Pain. 1991;47:295–8.CrossRef
36.
Zhao SZ, Chung F, Hanna DB, Raymundo AL, Cheung RY, Chen C. Dose-response relationship between opioid use and adverse effects after ambulatory surgery. J Pain Symptom Manag. 2004;28:35–46.CrossRef
37.
38.
Shyr MH, Hsu JC, Wu YW, Hui YL, Tan PC. P6 acupoint injection reduced postoperative nausea and vomiting. Anacsth Sinica. 1990;28:361–5.
39.
Dundek JW, Cheskutt WN, Ghaly RG, Lynas AGA. Traditional Chinese acupuncture a potentially useful antiemetic? Br Med. 1986;293:583–4.CrossRef
40.
Wang XQ, Yu JL, Du ZY, Xu R, Jiang CC, Gao X. Electroacupoint stimulation for postoperative nausea and vomiting in patients undergoing supratentorial craniotomy. J Neurosurg Anesthesiol. 2010;22:128–31.CrossRef
Metadata
Title
The effect of TEAS on the quality of early recovery in patients undergoing gynecological laparoscopic surgery: a prospective, randomized, placebo-controlled trial
Authors
Xiangdi Yu
Fangxiang Zhang
Bingning Chen
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Trials / Issue 1/2020
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-019-3892-4

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