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BMC Complementary Medicine and Therapies
Published in: BMC Complementary Medicine and Therapies 1/2023

Open Access 01-12-2023 | Acupuncture | Research

Supportive care for cancer-related symptoms in pediatric oncology: a qualitative study among healthcare providers

Authors: Dana C. Mora, Miek C. Jong, Sara A. Quandt, Thomas A. Arcury, Agnete E. Kristoffersen, Trine Stub

Published in: BMC Complementary Medicine and Therapies | Issue 1/2023

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Abstract

Background

The aim of this study is to gain insight into the clinical experiences and perceptions that pediatric oncology experts, conventional healthcare providers, and complementary and alternative medicine (CAM) providers in Norway, Canada, Germany, the Netherlands, and the United States have with the use of supportive care, including CAM among children and adolescents with cancer.

Methods

A qualitative study was conducted using semi-structured in-depth interviews (n = 22) with healthcare providers with clinical experience working with CAM and/or other supportive care among children and adolescents with cancer from five different countries. Participants were recruited through professional associations and personal networks. Systematic content analysis was used to delineate the main themes. The analysis resulted in three themes and six subthemes.

Results

Most participants had over 10 years of professional practice. They mostly treated children and adolescents with leukemia who suffered from adverse effects of cancer treatment, such as nausea and poor appetite. Their priorities were to identify the parents' treatment goals and help the children with their daily complaints. Some modalities frequently used were acupuncture, massage, music, and play therapy. Parents received information about supplements and diets in line with their treatment philosophies. They received education from the providers to mitigate symptoms and improve the well-being of the child.

Conclusions

Clinical experiences of pediatric oncology experts, conventional health care providers, and CAM providers give an understanding of how supportive care modalities, including CAM, are perceived in the field and how they can be implemented as adaptational tools to manage adverse effects and to improve the quality of life of children diagnosed with cancer and the families.
Literature
1.
Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Bray F, Hesseling P, Shin HY, Stiller CA, Bouzbid S, et al. International incidence of childhood cancer, 2001–10: a population-based registry study. Lancet Oncol. 2017;18(6):719–31.PubMedPubMedCentralCrossRef
2.
Bhakta N, Force LM, Allemani C, Atun R, Bray F, Coleman MP, Steliarova-Foucher E, Frazier AL, Robison LL, Rodriguez-Galindo C, et al. Childhood cancer burden: a review of global estimates. Lancet Oncol. 2019;20(1):e42–53.PubMedCrossRef
3.
4.
De Angelis R, Sant M, Coleman MP, Francisci S, Baili P, Pierannunzio D, Trama A, Visser O, Brenner H, Ardanaz E, et al. Cancer survival in Europe 1999–2007 by country and age: results of EUROCARE-5—a population-based study. Lancet Oncol. 2014;15(1):23–34.PubMedCrossRef
5.
Jemal A, Vineis P, Bray B, Torre L, Forman D. The Cancer Atlas New-York: Cancer in Children. 2015.
6.
7.
Howard SC, Zaidi A, Cao X, Weil O, Bey P, Patte C, Samudio A, Haddad L, Lam CG, Moreira C, et al. The My Child Matters programme: effect of public–private partnerships on paediatric cancer care in low-income and middle-income countries. Lancet Oncol. 2018;19(5):e252–66.PubMedCrossRef
8.
Lissauer T, Clayden G. Pædiatri. English: Pedriatrics. Copenhagen: FADL’s forlag; 2016.
9.
10.
11.
12.
Radossi AL, Taromina K, Marjerrison S, Diorio CJ, Similio R, Njuguna F, Afungchwi GM, Ladas EJ. A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative. Support Care Cancer. 2018;26(2):375–91.PubMedCrossRef
13.
Wiesener S, Falkenberg T, Hegyi G, Hök J, Roberti di Sarsina P, Fønnebø V. Legal Status and Regulation of Complementary and Alternative Medicine in Europe. Complement Med Res. 2012;19(suppl 2)(Suppl. 2):29–36.CrossRef
14.
Kania-Richmond A, Metcalfe A. Integrative health care - What are the relevant health outcomes from a practice perspective? A survey. BMC Complement Altern Med. 2017;17(1):548–548.PubMedPubMedCentralCrossRef
15.
Reindl TK, Geilen W, Hartmann R, Wiebelitz KR, Kan G, Wilhelm L, Lugauer S, Behrens C, Weiberlenn T, Hasan C, et al. Acupuncture against chemotherapy-induced nausea and vomiting in pediatric oncology Interim results of a multicenter crossover study. Support Care Cancer. 2006;14(2):172–6.PubMedCrossRef
16.
Gottschling S, Reindl TK, Meyer S, Berrang J, Henze G, Graeber S, Ong MF, Graf N. Acupuncture to alleviate chemotherapy-induced nausea and vomiting in pediatric oncology - a randomized multicenter crossover pilot trial. Klin Padiatr. 2008;220(6):365–70.PubMedCrossRef
17.
Mora DC, Overvåg G, Jong MC, Kristoffersen AE, Stavleu DC, Liu J, Stub T. Complementary and alternative medicine modalities used to treat adverse effects of anti-cancer treatment among children and young adults: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther. 2022;22(1):1–21.CrossRef
18.
Stub T, Arcury TA, Kristoffersen AE, Jong MC, Quandt SA: Parents of children with cancer: Strategies for managing care of sick child in the context of family life. Unpublished data 2019.
19.
Brown PR, Alaszewski A, Swift T, Nordin A. Actions speak louder than words: the embodiment of trust by healthcare professionals in gynae-oncology. Sociol Health Illn. 2011;33(2):280–95.PubMedCrossRef
20.
Stub T, Quandt SA, Arcury TA, Sandberg JC, Kristoffersen AE. Attitudes and knowledge about direct and indirect risks among conventional and complementary health care providers in cancer care. BMC Complement Altern Med. 2018;18(1):44.PubMedPubMedCentralCrossRef
21.
Dwyer JM. Is it ethical for medical practitioners to prescribe alternative and complementary treatments that may lack an evidence base? - No. Med J Aust. 2011;195(2):79.PubMedCrossRef
22.
Joyce P, Wardle J, Zaslawski C. Medical student attitudes towards complementary and alternative medicine (CAM) in medical education: a critical review. J Complement Integr Med. 2016;13(4):333–45.PubMedCrossRef
23.
24.
Quinn Patton M. Qualitative research & evaluation methods. In: Integrating theory and practice. California: SAGE publications, Inc; 2015.
25.
Kvale S, Brinkmann S, Anderssen TM, Rygge JF. Det kvalitative forskningsintervju. English: The qualitative research interview. Oslo: Gyldendal akademiske forlag; 2009.
26.
Fønnebø V, Grimsgaard S, Walach H, Ritenbaugh C, Norheim AJ, MacPherson H, Lewith G, Launsø L, Koithan M, Falkenberg T, et al. Researching complementary and alternative treatments - the gatekeepers are not at home. BMC Med Res Methodol. 2007;7(7):1–6.
27.
Malterud K. Qualitative research: standards, challenges, and guidelines. Lancet. 2001;11(358 9280):483–8.CrossRef
28.
Magnussen J, Vrangbaek K, Saltman R. EBOOK: Nordic Health Care Systems: Recent Reforms and Current Policy Challenges: McGraw-Hill Education (UK). 2009.
29.
Marchildon GP, Allin S, Merkur S. Canada: Health system review. Health Syst Transit. 2020;22(3):1–194.PubMed
30.
31.
OECD/European Observatory on Health Systems and Policies. Netherlands: Country Health Profile 2019. Paris/Brussels: State of Health in the EU, OECD Publishing/European Observatory on Health Systems and Policies; 2019. https://​doi.​org/​10.​1787/​9ac45ee0-en.
32.
World Health Organization. Regional Office for E, European Observatory on Health S, Policies, Rice T, Rosenau P, Unruh LY, Barnes AJ, Saltman RB, van Ginneken E. United States of America: health system review. Copenhagen: World Health Organization. Regional Office for Europe; 2013.
33.
Patton MQ. Qualitative research & evaluation methods: Integrating theory and practice. California: Sage publications; 2014.
34.
Stub T, Kristoffersen AE, Overvåg G, Jong MC. An integrative review on the information and communication needs of parents of children with cancer regarding the use of complementary and alternative medicine. BMC Complement Med Ther. 2020;20(1):90.PubMedPubMedCentralCrossRef
35.
Stub T, Quandt SA, Kristoffersen AE, Jong MC, Arcury TA. Communication and information needs about complementary and alternative medicine: a qualitative study of parents of children with cancer. BMC Complement Med Ther. 2021;21(1):85.PubMedPubMedCentralCrossRef
36.
Stub T, Kiil MA, Lie B, Kristoffersen AE, Weiss T, Hervik JB, Musial F. Combining psychotherapy with craniosacral therapy for severe traumatized patients: A qualitative study from an outpatient clinic in Norway. Complement Ther Med. 2020;49:102320.PubMedCrossRef
37.
Quandt SA, Sandberg JC, Graham A, Mora DC, Stub T, Arcury TA. Mexican Sobadores in North Carolina: Manual Therapy in a New Settlement Context. J Immigr Minor Health. 2017;19(5):1186–95.PubMedPubMedCentralCrossRef
38.
39.
Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15:1277–88.PubMedCrossRef
40.
Richards L. Handling Qualitative Data: A Practical Guide. London: Sage Publications; 2005. (ISBN 0-7619-4259-9).
41.
Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007;19(6):349–57.PubMedCrossRef
42.
43.
Ergil KV, Micozzi MS. 5 - Qi in China’s traditional medicine: the example of tuina. In: Mayor D, Micozzi MS, editors. Energy Medicine East and West. Edinburgh: Churchill Livingstone; 2011. p. 65–71.CrossRef
44.
45.
46.
Rutert B, Stritter W, Eggert A, Auge U, Laengler A, Seifert G, Holmberg C. Development of an Integrative Care Program in a Pediatric Oncology Unit. Complement Med Res. 2021;28(2):131–8.PubMedCrossRef
47.
Längler A, Zuzak TJ. Complementary and alternative medicine in paediatrics in daily practice—A European perspective. Complement Ther Med. 2013;21:S26–33.PubMedCrossRef
48.
Jacobsen R, Fønnebø VM, Foss N, Kristoffersen AE. Use of complementary and alternative medicine within Norwegian hospitals. BMC Complement Altern Med. 2015;15(1):275.PubMedPubMedCentralCrossRef
49.
50.
51.
52.
53.
Bishop FL, Prescott P, Chan YK, Saville J, von Elm E, Lewith GT. Prevalence of Complementary Medicine Use in Pediatric Cancer: A Systematic Review. Pediatrics. 2010;125(4):768–76.PubMedCrossRef
54.
Alnafia A, Binyousef FH, Algwaiz A, Almazyed A, Alduaylij T, Alolaiwi O, Alajlan A, Alsuhaibani M, Alenazi KA. Attitudes Towards Complementary and Alternative Medicine Among Pediatricians in Saudi Arabia. Cureus. 2021;13(12):e20486.PubMedPubMedCentral
55.
Langler A, Boeker R, Kameda G, Seifert G, Edelhauser F, Ostermann T. Attitudes and beliefs of paediatric oncologists regarding complementary and alternative therapies. Complement Ther Med. 2013;21(SUPPL.1):S10–9.PubMedCrossRef
56.
Roth M, Lin J, Kim M, Moody K. Pediatric Oncologists’ Views Toward the Use of Complementary and Alternative Medicine in Children With Cancer. J Pediatr Hematol Oncol. 2009;31(3):177–82.PubMedCrossRef
57.
Varejao CDS, Santo F. Laser Acupuncture for Relieving Nausea and Vomiting in Pediatric Patients Undergoing Chemotherapy: A Single-Blind Randomized Clinical Trial. J Pediatr Oncol Nurs. 2019;36(1):44–54.PubMedCrossRef
58.
Jones E, Isom S, Kemper KJ, McLean TW. Acupressure for chemotherapy-associated nausea and vomiting in children. J Soc Integr Oncol. 2008;6(4):141–5.PubMed
59.
Ghezelbash S, Khosravi M. Acupressure for nausea-vomiting and fatigue management in acute lymphoblastic leukemia children. J Nurs Midwifery Sci. 2017;4(3):75–81.CrossRef
60.
Evans A, Garretson C, Pedroja E, Malvar J, Margol A, Sposto R, Nelson MB. The use of aromatherapy to reduce chemotherapy-induced nausea in children with cancer; A randomized, double blind, placebo controlled trial. Neuro Oncol. 2016;18(Supplement 33):iii137.PubMedCentral
61.
Wong J, Ghiasuddin A, Kimata C, Patelesio B, Siu A. The Impact of Healing Touch on Pediatric Oncology Patients. Integr Cancer Ther. 2013;12(1):25–30.PubMedCrossRef
62.
Facchini M, Ruini C. The role of music therapy in the treatment of children with cancer: A systematic review of literature. Complement Ther Clin Pract. 2021;42:101289.PubMedCrossRef
63.
Ibrahim HA, Amal AA. The Effectiveness of Play Therapy in Hospitalized Children with Cancer: Systematic Review. J Nurs Pract. 2020;3(2):233–43.CrossRef
64.
Purrezaian M, Purrezaian H. Group psychodrama for children with leukemia: A brief report. J Psychosoc Oncol. 2022;40(1):131–5.PubMedCrossRef
65.
Mora DC, Kristoffersen AE, Overvåg G, Jong MC, Mentink M, Liu J, Stub T. Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review. Integr Cancer Ther. 2022;21:15347354221105564.PubMedPubMedCentralCrossRef
66.
Molassiotis A, Fernadez-Ortega P, Pud D, Ozden G, Scott JA, Panteli V, Margulies A, Browall M, Magri M, Selvekerova S. Use of complementary and alternative medicine in cancer patients: a European survey. Ann Oncol. 2005;16(4):655–63.PubMedCrossRef
67.
King N, Balneaves LG, Levin GT, Nguyen T, Nation JG, Card C, Truant T, Carlson LE. Surveys of cancer patients and cancer health care providers regarding complementary therapy use, communication, and information needs. Integr Cancer Ther. 2015;14(6):515–24.PubMedCrossRef
68.
Truant T, Bottorff JL. Decision making related to complementary therapies: a process of regaining control. Patient Educ Couns. 1999;38(2):131–42.PubMedCrossRef
69.
70.
71.
Malterud K. Kvalitative metoder i medisinsk forskning: en innføring: Universitetsforlaget. 2011.
72.
Pritchard-Jones K, Pieters R, Reaman GH, Hjorth L, Downie P, Calaminus G, Naafs-Wilstra MC, Steliarova-Foucher E. Sustaining innovation and improvement in the treatment of childhood cancer: lessons from high-income countries. Lancet Oncol. 2013;14(3):e95–103.PubMedCrossRef
Metadata
Title
Supportive care for cancer-related symptoms in pediatric oncology: a qualitative study among healthcare providers
Authors
Dana C. Mora
Miek C. Jong
Sara A. Quandt
Thomas A. Arcury
Agnete E. Kristoffersen
Trine Stub
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Complementary Medicine and Therapies / Issue 1/2023
Electronic ISSN: 2662-7671
DOI
https://doi.org/10.1186/s12906-023-03924-x

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