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Published in: Critical Care 1/2004

01-02-2004 | Poster presentation

Activity of the lipoxygenase inhibitor 1-phenyl-3-pyrazolidinone (phenidone) and derivatives on the expression of adhesion molecules on human umbilical vascular endothelial cells

Authors: T Schroeder, F Neuscheler, C Karcher, H Dieterich, B Nohé

Published in: Critical Care | Special Issue 1/2004

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Excerpt

Leucocyte adhesion contributes to perfusion abnormalities and tissue damage, and during trauma, shock or overwhelming inflammation. This study was performed to determine whether the lipoxygenase inhibitor phenidone and derivatives decrease the expression of adhesion molecules on stimulated endothelial cells and attenuate leucocyte–endothelial interactions under flow in vitro. …
Metadata
Title
Activity of the lipoxygenase inhibitor 1-phenyl-3-pyrazolidinone (phenidone) and derivatives on the expression of adhesion molecules on human umbilical vascular endothelial cells
Authors
T Schroeder
F Neuscheler
C Karcher
H Dieterich
B Nohé
Publication date
01-02-2004
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2004
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc2660

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