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Acta Diabetologica
Published in: Acta Diabetologica 2/2014

01-04-2014 | Letter to the Editor

ACP1–ADA1 interaction in type 2 diabetes: a study in coronary artery disease

Authors: F. Gloria-Bottini, M. Banci, P. Saccucci, A. Neri, E. Bottini, A. Magrini

Published in: Acta Diabetologica | Issue 2/2014

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Excerpt

ACP1 (acid phosphatase locus 1 also called cLMWPTP: cytosolic low-molecular-weight phosphotyrosine protein phosphatase) is a polymorphic enzyme that acts as phosphotyrosine phosphatase contributing to the regulation of phosphotyrosine kinases activity [1]. …
Literature
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Bottini N, Bottini E, Gloria-Bottini F, Mustelin T (2002) Low-molecular-weight protein tyrosine phosphatase and human disease: in search of biochemical mechanisms. Arch Immunol Ther Exp 50:95–104
2.
Stefani M, Caselli A, Bucciantini M, Pazzagli L, Dolfi F, Camici G et al (1993) Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine phosphatase isoenzymes. FEBBS 326:131–134CrossRef
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Low PS, Allen DP, Zinocheck TF, Chari P, Willardson BM, Geahlen RL et al (1987) Tyrosine phosphorylation of band 3 inhibits peripheral protein binding. J Biol Chem 262:4592–4595PubMed
4.
Pandey SK, Yu XX, Watts LM, Michael MD, Sloop KW, Rivard AR et al (2007) Reduction of low molecular weight protein-tyrosine phosphatase expression improves hyperglycemia and insulin sensitivity in obese mice. J Biol Chem 282:14291–14299PubMedCrossRef
5.
Gloria-Bottini F, Magrini A, Di Renzo L, De Lorenzo A, Bergamaschi A, Bottini E (2010) Body mass index and acid phosphatase locus 1 in diabetic disorders. Acta Diabetol 47(Suppl 1):139–143PubMedCrossRef
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Gloria-Bottini F, Gerlini G, Lucarini N, Borgiani P, Amante A, La Torre M et al (1996) Phosphotyrosine protein phosphatases and diabetic pregnancy. An association between low molecular weight acid phosphatase (ACP1) and degree of glycemic control. Experientia 52:340–343PubMedCrossRef
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Iannaccone U, Bergamaschi A, Magrini A, Marino G, Bottini N, Lucarelli P et al (2005) Serum glucose concentration and ACP1 genotype in healthy adult subjects. Metabolism 54:891–894PubMedCrossRef
8.
Lucarini N, Borgiani P, Ballarini P, Bottini E (1989) Erythrocyte acid phosphatase (ACP1) activity. In vitro modulation by adenosine and inosine and effects of adenosine deaminase (ADA) polymorphism. Hum Genet 81:185–187PubMedCrossRef
9.
Fuchs KR, Shekels LL, Bernlohr DA (1992) Analysis of the ACP1 gene product: classification as an FMN phosphatase. Biochem Biophys Res Commun 189:1598–1605PubMedCrossRef
Metadata
Title
ACP1–ADA1 interaction in type 2 diabetes: a study in coronary artery disease
Authors
F. Gloria-Bottini
M. Banci
P. Saccucci
A. Neri
E. Bottini
A. Magrini
Publication date
01-04-2014
Publisher
Springer Milan
Published in
Acta Diabetologica / Issue 2/2014
Print ISSN: 0940-5429
Electronic ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-011-0345-2

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