Top

Published in:

01-02-2019 | Original Article

Accuracy of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) score as an objective assessment tool for predicting return-to-work status after head and neck cancer in male survivors

Authors: Yu-Hao Lee, Kwang-Hwa Chang, Reuben Escorpizo, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Shih-Wei Huang, Tsan-Hon Liou

Published in: Supportive Care in Cancer | Issue 2/2019

Abstract

Purpose

The objective of this nationwide study in Taiwan was to predict work participation by using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) score as an objective assessment tool.

Method

Data from between July 2012 and July 2017 regarding 1206 male head and neck cancer (HNC) survivors with disability aged < 50 years were obtained from the Taiwan Data Bank of Persons with Disability (TDPD). Demographic data and the WHODAS 2.0 scores were analyzed to compare employment statuses among HNC survivors.

Results

The WHODAS 2.0 scores in all the domains were lower in unemployed than in employed HNC survivors (p < 0.001). The receiver operating characteristic (ROC) curve revealed that the summary WHODAS 2.0 score (area under curve > 0.8) was an extremely accurate predictive tool. Binary logistic regression revealed that the severity levels of impairment and standardized WHODAS 2.0 summary scores less than the cutoff value (27.81) were predictors for the return-to-work (RTW) status of HNC survivors with disability in the working age group.

Conclusions

The WHODAS 2.0 score is an objective quantitative assessment tool for evaluating the RTW possibility among these patient groups.

Taiwan cancer registry (2017) Cancer incidence and mortality rates in Taiwan. Taiwan cancer registry. Retrieved from http://tcr.cph.ntu.edu.tw/main.php?Page=N2,

Chiang CJ, Chen YC, Chen CJ, You SL, Lai MS (2010) Cancer trends in Taiwan. Jpn J Clin Oncol 40(10):897–904. https://doi.org/10.1093/jjco/hyq057 CrossRefPubMed

Frisch M, Hjalgrim H, Jaeger AB, Biggar RJ (2000) Changing patterns of tonsillar squamous cell carcinoma in the United States. Cancer causes & control: CCC 11(6):489–495CrossRef

Chaturvedi AK, Anderson WF, Lortet-Tieulent J, Curado MP, Ferlay J, Franceschi S, Rosenberg PS, Bray F, Gillison ML (2013) Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers. J Clin Oncol 31(36):4550–4559. https://doi.org/10.1200/JCO.2013.50.3870 CrossRefPubMedPubMedCentral

Taibi R, Lleshi A, Barzan L, Fiorica F, Leghissa M, Vaccher E, De Paoli P, Franchin G, Berretta M, Tirelli U (2014) Head and neck cancer survivors patients and late effects related to oncologic treatment: update of literature. Eur Rev Med Pharmacol Sci 18(10):1473–1481PubMed

Health Promotion Administration of Taiwan Ministry of Health and Welfare (2014) Cancer registry annual report 2014. Retrieved from http://www.hpa.gov.tw/Pages/ashx/File.ashx?FilePath=~/File/Attach/7330/File_6792.pdf

Ringash J (2015) Survivorship and quality of life in head and neck cancer. J Clin Oncol 33(29):3322–3327. https://doi.org/10.1200/JCO.2015.61.4115 CrossRefPubMed

Pearce A, Timmons A, O'Sullivan E, Gallagher P, Gooberman-Hill R, Thomas AA, Molcho M, Butow P, Sharp L (2015) Long-term workforce participation patterns following head and neck cancer. J Cancer Surviv 9(1):30–39. https://doi.org/10.1007/s11764-014-0382-2 CrossRefPubMed

Isaksson J, Wilms T, Laurell G, Fransson P, Ehrsson YT (2016) Meaning of work and the process of returning after head and neck cancer. Support Care Cancer 24(1):205–213. https://doi.org/10.1007/s00520-015-2769-7 CrossRefPubMed

10.

Koch R, Wittekindt C, Altendorf-Hofmann A, Singer S, Guntinas-Lichius O (2015) Employment pathways and work-related issues in head and neck cancer survivors. Head Neck 37(4):585–593. https://doi.org/10.1002/hed.23640 CrossRefPubMed

11.

Pearce AM, Hanly P, Timmons A, Walsh PM, O'Neill C, O'Sullivan E, Gooberman-Hill R, Thomas AA, Gallagher P, Sharp L (2015) Productivity losses associated with head and neck cancer using the human capital and friction cost approaches. Applied health economics and health policy 13(4):359–367. https://doi.org/10.1007/s40258-015-0155-8 CrossRefPubMed

12.

Kjaer T, Boje CR, Olsen MH, Overgaard J, Johansen J, Ibfelt E, Steding-Jessen M, Johansen C, Dalton SO (2013) Affiliation to the work market after curative treatment of head-and-neck cancer: a population-based study from the DAHANCA database. Acta oncologica (Stockholm, Sweden) 52(2):430–439. https://doi.org/10.3109/0284186x.2012.746469 CrossRef

13.

Gallagher KK, Sacco AG, Lee JS, Taylor R, Chanowski EJ, Bradford CR, Prince ME, Moyer JS, Wolf GT, Worden FP, Eisbruch A, Chepeha DB (2015) Association between multimodality neck treatment and work and leisure impairment: a disease-specific measure to assess both impairment and rehabilitation after neck dissection. JAMA otolaryngology-- head & neck surgery 141(10):888–893. https://doi.org/10.1001/jamaoto.2015.2049 CrossRef

14.

Ustun TB, Chatterji S, Kostanjsek N, Rehm J, Kennedy C, Epping-Jordan J, Saxena S, von Korff M, Pull C, Project WNJ (2010) Developing the World Health Organization Disability Assessment Schedule 2.0. Bull World Health Organ 88(11):815–823. https://doi.org/10.2471/BLT.09.067231 CrossRefPubMedPubMedCentral

15.

Federici S, Bracalenti M, Meloni F, Luciano JV (2017) World Health Organization disability assessment schedule 2.0: an international systematic review. Disabil Rehabil 39(23):2347–2380. https://doi.org/10.1080/09638288.2016.1223177 CrossRefPubMed

16.

Chiu WT, Yen CF, Teng SW, Liao HF, Chang KH, Chi WC, Wang YH, Liou TH (2013) Implementing disability evaluation and welfare services based on the framework of the International Classification of Functioning, Disability and Health: experiences in Taiwan. BMC Health Serv Res 13:416. https://doi.org/10.1186/1472-6963-13-416 CrossRefPubMedPubMedCentral

17.

Chiu TY, Yen CF, Chou CH, Lin JD, Hwang AW, Liao HF, Chi WC (2014) Development of traditional Chinese version of World Health Organization disability assessment schedule 2.0 36-item (WHODAS 2.0) in Taiwan: validity and reliability analyses. Res Dev Disabil 35(11):2812–2820. https://doi.org/10.1016/j.ridd.2014.07.009 CrossRefPubMed

18.

Yen CF, Hwang AW, Liou TH, Chiu TY, Hsu HY, Chi WC, Wu TF, Chang BS, Lu SJ, Liao HF, Teng SW, Chiu WT (2014) Validity and reliability of the Functioning Disability Evaluation Scale-Adult Version based on the WHODAS 2.0—36 items. J Formos Med Assoc 113(11):839–849. https://doi.org/10.1016/j.jfma.2014.08.008 CrossRefPubMed

19.

Stergiou-Kita M, Grigorovich A, Tseung V, Milosevic E, Hebert D, Phan S, Jones J (2014) Qualitative meta-synthesis of survivors' work experiences and the development of strategies to facilitate return to work. J Cancer Surviv 8(4):657–670. https://doi.org/10.1007/s11764-014-0377-z CrossRefPubMed

20.

Bolt S, Eadie T, Yorkston K, Baylor C, Amtmann D (2016) Variables associated with communicative participation after head and neck cancer. JAMA otolaryngology-head & neck surgery 142(12):1145–1151. https://doi.org/10.1001/jamaoto.2016.1198 CrossRef

21.

Welsh LC, Dunlop AW, McGovern T, McQuaid D, Dean JA, Gulliford SL, Bhide SA, Harrington KJ, Nutting CM, Newbold KL (2014) Neurocognitive function after (chemo)-radiotherapy for head and neck cancer. Clinical oncology (Royal College of Radiologists (Great Britain)) 26(12):765–775. https://doi.org/10.1016/j.clon.2014.06.014 CrossRef

22.

De Felice F, Blanchard P (2017) Radiation-induced neurocognitive dysfunction in head and neck cancer patients. Tumori 103(4):319–324. https://doi.org/10.5301/tj.5000678 CrossRefPubMed

23.

Williams AM, Lindholm J, Siddiqui F, Ghanem TA, Chang SS (2017) Clinical assessment of cognitive function in patients with head and neck cancer: prevalence and correlates. Otolaryngol Head Neck Surg:194599817709235. doi:https://doi.org/10.1177/0194599817709235

24.

Couch M, Lai V, Cannon T, Guttridge D, Zanation A, George J, Hayes DN, Zeisel S, Shores C (2007) Cancer cachexia syndrome in head and neck cancer patients: part I. Diagnosis, impact on quality of life and survival, and treatment. Head Neck 29(4):401–411. https://doi.org/10.1002/hed.20447 CrossRefPubMed

25.

Lonbro S, Dalgas U, Primdahl H, Johansen J, Nielsen JL, Overgaard J, Overgaard K (2013) Lean body mass and muscle function in head and neck cancer patients and healthy individuals—results from the DAHANCA 25 study. Acta oncologica (Stockholm, Sweden) 52(7):1543–1551. https://doi.org/10.3109/0284186x.2013.822553 CrossRef

26.

Silver HJ, Dietrich MS, Murphy BA (2007) Changes in body mass, energy balance, physical function, and inflammatory state in patients with locally advanced head and neck cancer treated with concurrent chemoradiation after low-dose induction chemotherapy. Head Neck 29(10):893–900. https://doi.org/10.1002/hed.20607 CrossRefPubMed

27.

Helmio PM, Suominen S, Vuola J, Back L, Makitie AA (2010) Clinical outcome of reconstruction of the lateral oropharyngeal wall with an anterolateral thigh free flap. Journal of plastic surgery and hand surgery 44(4–5):186–190. https://doi.org/10.3109/02844311.2010.484976 CrossRefPubMed

28.

Yildirim S, Gideroglu K, Aydogdu E, Avci G, Akan M, Akoz T (2006) Composite anterolateral thigh-fascia lata flap: a good alternative to radial forearm-palmaris longus flap for total lower lip reconstruction. Plast Reconstr Surg 117(6):2033–2041. https://doi.org/10.1097/01.prs.0000210663.59939.02 CrossRefPubMed

29.

Eades M, Chasen M, Bhargava R (2009) Rehabilitation: long-term physical and functional changes following treatment. Semin Oncol Nurs 25(3):222–230. https://doi.org/10.1016/j.soncn.2009.05.006 CrossRefPubMed

30.

Ghiam MK, Mannion K, Dietrich MS, Stevens KL, Gilbert J, Murphy BA (2017) Assessment of musculoskeletal impairment in head and neck cancer patients. Support Care Cancer 25(7):2085–2092. https://doi.org/10.1007/s00520-017-3603-1 CrossRefPubMed

31.

Gane EM, O'Leary SP, Hatton AL, Panizza BJ, McPhail SM (2017) Neck and upper limb dysfunction in patients following neck dissection: looking beyond the shoulder Otolaryngol Head Neck Surg:194599817721164. doi:https://doi.org/10.1177/0194599817721164

32.

Espenel S, Garcia MA, Guy JB, Vallard A, Ben Mrad M, Langrand-Escure J, El Meddeb HA, Trone JC, Xia Y, Rancoule C, Magne N (2017) Ototoxicity in head and neck cancers after radiotherapy and chemoradiotherapy: from primary prevention to tertiary prevention. Cancer Radiother 21(1):77–83. https://doi.org/10.1016/j.canrad.2016.08.130 CrossRefPubMed

33.

Hung TM, Lin CR, Chi YC, Lin CY, Chen EY, Kang CJ, Huang SF, Juang YY, Huang CY, Chang JT (2017) Body image in head and neck cancer patients treated with radiotherapy: the impact of surgical procedures. Health Qual Life Outcomes 15(1):165. https://doi.org/10.1186/s12955-017-0740-7 CrossRefPubMedPubMedCentral

34.

Fan CY, Chao HL, Lin CS, Huang WY, Chen CM, Lin KT, Lin CL, Kao CH (2017) Risk of depressive disorder among patients with head and neck cancer: a nationwide population-based study. Head Neck 40:312–323. https://doi.org/10.1002/hed.24961 CrossRefPubMed

35.

Dewa CS, Trojanowski L, Tamminga SJ, Ringash J, McQuestion M, Hoch JS (2017) Work-related experiences of head and neck cancer survivors: an exploratory and descriptive qualitative study. Disabil Rehabil:1–7. doi:https://doi.org/10.1080/09638288.2017.1291764

36.

de Boer AG, Taskila TK, Tamminga SJ, Feuerstein M, Frings-Dresen MH, Verbeek JH (2015) Interventions to enhance return-to-work for cancer patients. The Cochrane database of systematic reviews (9):Cd007569. doi:https://doi.org/10.1002/14651858.CD007569.pub3

37.

Agarwal J, Krishnatry R, Chaturvedi P, Ghosh-Laskar S, Gupta T, Budrukkar A, Murthy V, Deodhar J, Nair D, Nair S, Dikshit R, D'Cruz AK (2017) Survey of return to work of head and neck cancer survivors: a report from a tertiary cancer center in India. Head Neck 39(5):893–899. https://doi.org/10.1002/hed.24703 CrossRefPubMed

38.

Directorate-General of Budget Accounting and Statistics of Taiwan Executive Yuan (2017) Unemployment rate by educational attainment. Directorate-General of Budget, Accounting and Statistics (DGBAS) of Executive Yuan, Taiwan. Retrieved from http://eng.stat.gov.tw/public/data/dgbas04/bc4/english/table/tab09.xls

39.

Chang MJ, Su CY (2014) Hysteresis versus natural rate in Taiwan's unemployment: evidence from the educational attainment categories. Econ Model 43:293–304. https://doi.org/10.1016/j.econmod.2014.08.015 CrossRef

40.

Yang CC, Chan SJ (2017) Is higher education expansion related to increasing unemployment rates? A comparative analysis of Japan, South Korea, and Taiwan. Int J Chin Educ 5(2):162–186. https://doi.org/10.1163/22125868-12340066 CrossRef

Title: Accuracy of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) score as an objective assessment tool for predicting return-to-work status after head and neck cancer in male survivors
Authors: Yu-Hao Lee
Kwang-Hwa Chang
Reuben Escorpizo
Wen-Chou Chi
Chia-Feng Yen
Hua-Fang Liao
Shih-Wei Huang
Tsan-Hon Liou
Publication date: 01-02-2019
Publisher: Springer Berlin Heidelberg
Published in: Supportive Care in Cancer / Issue 2/2019
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-018-4322-y

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras

Prof. Fabrice Barlesi

Developed by: Springer Medicine

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Method

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 2/2019

IMproved MAnagement (IM-MA study) in cancer-related pain: the value of a joint approach by an integrated team of radiotherapist and anesthetist

The prevalence and determinants of return to work in head and neck cancer survivors

“It sort of hit me like a baseball bat between the eyes”: a qualitative study of the psychosocial experiences of mesothelioma patients and carers

Examining trajectories of anxiety in men with prostate cancer faced with complex treatment decisions

Sensory preferences of supplemented food products among cancer patients: a systematic review

“Improving to where?”: treatment-related health risks and perceptions of the future among adolescents and young adults after hematopoietic cell transplantation

Keynote webinar | Spotlight on antibody–drug conjugates in cancer