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01-08-2007 | Experimental

Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners

Authors: Marco Das, Julia Ley-Zaporozhan, H. A. Gietema, Andre Czech, Georg Mühlenbruch, Andreas H. Mahnken, Markus Katoh, Annemarie Bakai, Marcos Salganicoff, Stefan Diederich, Mathias Prokop, Hans-Ulrich Kauczor, Rolf W. Günther, Joachim E. Wildberger

Published in: European Radiology | Issue 8/2007

Abstract

The purpose of this study was to compare the accuracy of an automated volumetry software for phantom pulmonary nodules across various 16-slice multislice spiral CT (MSCT) scanners from different vendors. A lung phantom containing five different nodule categories (intraparenchymal, around a vessel, vessel attached, pleural, and attached to the pleura), with each category comprised of 7–9 nodules (total, n = 40) of varying sizes (diameter 3–10 mm; volume 6.62 mm³–525 mm³), was scanned with four different 16-slice MSCT scanners (Siemens, GE, Philips, Toshiba). Routine and low-dose chest protocols with thin and thick collimations were applied. The data from all scanners were used for further analysis using a dedicated prototype volumetry software. Absolute percentage volume errors (APE) were calculated and compared. The mean APE for all nodules was 8.4% (±7.7%) for data acquired with the 16-slice Siemens scanner, 14.3% (±11.1%) for the GE scanner, 9.7% (±9.6%) for the Philips scanner and 7.5% (±7.2%) for the Toshiba scanner, respectively. The lowest APEs were found within the diameter size range of 5–10 mm and volumes >66 mm³. Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies.

Wormanns D, Ludwig K, Beyer F, Heindel W, Diederich S (2005) Detection of pulmonary nodules at multirow-detector CT: effectiveness of double reading to improve sensitivity at standard-dose and low-dose chest CT. Eur Radiol 15:14–22PubMedCrossRef

Valencia R, Denecke T, Lehmkuhl L, Fischbach F, Felix R, Knollmann F (2006) Value of axial and coronal maximum intensity projection (MIP) images in the detection of pulmonary nodules by multislice spiral CT: comparison with axial 1-mm and 5-mm slices. Eur Radiol 16:325–332PubMedCrossRef

Takashima S, Sone S, Li F, Maruyama Y, Hasegawa M, Kadoya M (2003) Indeterminate solitary pulmonary nodules revealed at population-based CT screening of the lung: using first follow-up diagnostic CT to differentiate benign and malignant lesions. AJR Am J Roentgenol 180:1255–1263PubMed

Tan BB, Flaherty KR, Kazerooni EA, Iannettoni MD (2003) The solitary pulmonary nodule. Chest 123:89S–96SPubMedCrossRef

Diederich S, Wormanns D, Semik M et al (2002) Screening for early lung cancer with low-dose spiral CT: prevalence in 817 asymptomatic smokers. Radiology 222:773–781PubMedCrossRef

Henschke CI, McCauley DI, Yankelevitz DF et al (1999) Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet 354:99–105PubMedCrossRef

Henschke CI, Naidich DP, Yankelevitz DF et al (2001) Early lung cancer action project: initial findings on repeat screenings. Cancer 92:153–159PubMedCrossRef

Sone S, Takashima S, Li F et al (1998) Mass screening for lung cancer with mobile spiral computed tomography scanner. Lancet 351:1242–1245PubMedCrossRef

Swensen SJ, Jett JR, Hartman TE et al (2003) Lung cancer screening with CT: Mayo Clinic experience. Radiology 226:756–761PubMedCrossRef

10.

Diederich S, Hansen J, Wormanns D (2005) Resolving small pulmonary nodules: CT features. Eur Radiol 15:2064–2069PubMedCrossRef

11.

MacMahon H, Austin JH, Gamsu G et al (2005) Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology 237:395–400PubMedCrossRef

12.

Bogot NR, Kazerooni EA, Kelly AM, Quint LE, Desjardins B, Nan B (2005) Interobserver and intraobserver variability in the assessment of pulmonary nodule size on CT using film and computer display methods. Acad Radiol 12:948–956PubMedCrossRef

13.

Marten K, Auer F, Schmidt S, Kohl G, Rummeny EJ, Engelke C (2006) Inadequacy of manual measurements compared to automated CT volumetry in assessment of treatment response of pulmonary metastases using RECIST criteria. Eur Radiol 16:781–790PubMedCrossRef

14.

Marten K, Engelke C, Grabbe E, Rummeny EJ (2004) [Flat-panel detector-based computed tomography: accuracy of experimental growth rate assessment in pulmonary nodules]. Rofo 176:752–757PubMed

15.

Marten K, Funke M, Engelke C (2004) Flat panel detector-based volumetric CT: prototype evaluation with volumetry of small artificial nodules in a pulmonary phantom. J Thorac Imaging 19:156–163PubMedCrossRef

16.

Wiemker R, Rogalla P, Blaffert T et al (2005) Aspects of computer-aided detection (CAD) and volumetry of pulmonary nodules using multislice CT. Br J Radiol 78 Spec No:S46–S56PubMedCrossRef

17.

Wormanns D, Kohl G, Klotz E et al (2004) Volumetric measurements of pulmonary nodules at multi-row detector CT: in vivo reproducibility. Eur Radiol 14:86–92PubMedCrossRef

18.

Yankelevitz DF, Reeves AP, Kostis WJ, Zhao B, Henschke CI (2000) Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation. Radiology 217:251–256PubMed

19.

Boll DT, Gilkeson RC, Fleiter TR, Blackham KA, Duerk JL, Lewin JS (2004) Volumetric assessment of pulmonary nodules with ECG-gated MDCT. AJR Am J Roentgenol 183:1217–1223PubMed

20.

Mullally W, Betke M, Wang J, Ko JP (2004) Segmentation of nodules on chest computed tomography for growth assessment. Med Phys 31:839–848PubMedCrossRef

21.

Bolte H, Riedel C, Jahnke T et al (2006) Reproducibility of computer-aided volumetry of artificial small pulmonary nodules in ex vivo porcine lungs. Invest Radiol 41:28–35PubMedCrossRef

22.

Goo JM, Tongdee T, Tongdee R, Yeo K, Hildebolt CF, Bae KT (2005) Volumetric measurement of synthetic lung nodules with multi-detector row CT: effect of various image reconstruction parameters and segmentation thresholds on measurement accuracy. Radiology 235:850–856PubMedCrossRef

23.

Ko JP, Rusinek H, Jacobs EL et al (2003) Small pulmonary nodules: volume measurement at chest CT-phantom study. Radiology 228:864–870PubMedCrossRef

24.

Shin HO, Blietz M, Frericks B, Baus S, Savellano D, Galanski M (2006) Insertion of virtual pulmonary nodules in CT data of the chest: development of a software tool. Eur Radiol 16:2567–2574 NovPubMedCrossRef

25.

Benjamin MS, Drucker EA, McLoud TC, Shepard JA (2003) Small pulmonary nodules: detection at chest CT and outcome. Radiology 226:489–493PubMedCrossRef

Title: Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners
Authors: Marco Das
Julia Ley-Zaporozhan
H. A. Gietema
Andre Czech
Georg Mühlenbruch
Andreas H. Mahnken
Markus Katoh
Annemarie Bakai
Marcos Salganicoff
Stefan Diederich
Mathias Prokop
Hans-Ulrich Kauczor
Rolf W. Günther
Joachim E. Wildberger
Publication date: 01-08-2007
Publisher: Springer-Verlag
Published in: European Radiology / Issue 8/2007
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-006-0562-1

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Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners

Abstract

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