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Published in: International Journal for Equity in Health 1/2017

Open Access 01-12-2017 | Research

Access to medicines and diagnostic tests integral in the management of diabetes mellitus and cardiovascular diseases in Uganda: insights from the ACCODAD study

Authors: Davis Kibirige, David Atuhe, Leaticia Kampiire, Daniel Ssekikubo Kiggundu, Pamela Donggo, Juliet Nabbaale, Raymond Mbayo Mwebaze, Robert Kalyesubula, William Lumu

Published in: International Journal for Equity in Health | Issue 1/2017

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Abstract

Background

Despite the burgeoning burden of diabetes mellitus (DM) and cardiovascular diseases (CVD) in low and middle income countries (LMIC), access to affordable essential medicines and diagnostic tests for DM and CVD still remain a challenge in clinical practice. The Access to Cardiovascular diseases, Chronic Obstructive pulmonary disease, Diabetes mellitus and Asthma Drugs and diagnostics (ACCODAD) study aimed at providing contemporary information about the availability, cost and affordability of medicines and diagnostic tests integral in the management of DM and CVD in Uganda.

Methods

The study assessed the availability, cost and affordability of 37 medicines and 19 diagnostic tests in 22 public hospitals, 23 private hospitals and 100 private pharmacies in Uganda. Availability expressed as a percentage, median cost of the available lowest priced generic medicine and the diagnostic tests and affordability in terms of the number of days’ wages it would cost the least paid public servant to pay for one month of treatment and the diagnostic tests were calculated.

Results

The availability of the medicines and diagnostic tests in all the study sites ranged from 20.1% for unfractionated heparin (UFH) to 100% for oral hypoglycaemic agents (OHA) and from 6.8% for microalbuminuria to 100% for urinalysis respectively. The only affordable tests were blood glucose, urinalysis and serum ketone, urea, creatinine and uric acid. Parenteral benzathine penicillin, oral furosemide, glibenclamide, bendrofluazide, atenolol, cardiac aspirin, digoxin, metformin, captopril and nifedipine were the only affordable drugs.

Conclusion

This study demonstrates that the majority of medicines and diagnostic tests essential in the management of DM and CVD are generally unavailable and unaffordable in Uganda. National strategies promoting improved access to affordable medicines and diagnostic tests and primary prevention measures of DM and CVD should be prioritised in Uganda.
Literature
3.
go back to reference Dalal S, Beunza J, Volmink J, Adebamowo C, Bajunirwe F, Njelekela M, et al. Noncommunicable diseases in sub-Saharan Africa: what we know now. Int J Epidemiol. 2011;40:885–901.CrossRefPubMed Dalal S, Beunza J, Volmink J, Adebamowo C, Bajunirwe F, Njelekela M, et al. Noncommunicable diseases in sub-Saharan Africa: what we know now. Int J Epidemiol. 2011;40:885–901.CrossRefPubMed
4.
go back to reference Sobngwi E, Ndour-Mbaye M, Boateng K, Ramaiya K, Njenga E, Diop S, et al. Type 2 diabetes control and complications in specialised diabetes care centres of six sub-Saharan African countries: the Diabcare Africa study. Diabetes Res Clin Pract. 2012;95:30–6.CrossRefPubMed Sobngwi E, Ndour-Mbaye M, Boateng K, Ramaiya K, Njenga E, Diop S, et al. Type 2 diabetes control and complications in specialised diabetes care centres of six sub-Saharan African countries: the Diabcare Africa study. Diabetes Res Clin Pract. 2012;95:30–6.CrossRefPubMed
5.
go back to reference Mendis S, Fukino K, Cameron A, Laing R, Filipe-Jr A, Khatib O, et al. The availability and affordability of selected essential medicines for chronic diseases in six low- and middle-income countries. Bull World Health Organ. 2007;85:279–88.CrossRefPubMedPubMedCentral Mendis S, Fukino K, Cameron A, Laing R, Filipe-Jr A, Khatib O, et al. The availability and affordability of selected essential medicines for chronic diseases in six low- and middle-income countries. Bull World Health Organ. 2007;85:279–88.CrossRefPubMedPubMedCentral
6.
go back to reference Jingi A, Noubiap J, Onana A, Nansseu J, Wang B, Kingue S, et al. Access to diagnostic tests and essential medicines for cardiovascular diseases and diabetes care: cost, availability and affordability in the West Region of Cameroon. PLoS One. 2014;9(11):e111812.CrossRefPubMedPubMedCentral Jingi A, Noubiap J, Onana A, Nansseu J, Wang B, Kingue S, et al. Access to diagnostic tests and essential medicines for cardiovascular diseases and diabetes care: cost, availability and affordability in the West Region of Cameroon. PLoS One. 2014;9(11):e111812.CrossRefPubMedPubMedCentral
7.
go back to reference van Mourik M, Cameron A, Ewen M, Laing R. Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data. BMC Cardiovasc Disord. 2010;10:25.CrossRefPubMedPubMedCentral van Mourik M, Cameron A, Ewen M, Laing R. Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data. BMC Cardiovasc Disord. 2010;10:25.CrossRefPubMedPubMedCentral
8.
go back to reference Cameron A, Ewen M, Ross-Degnan D, Ball D, Laing R. Medicine prices, availability, and aff ordability in 36 developing and middle-income countries: a secondary analysis. Lancet. 2009;373:240–9.CrossRefPubMed Cameron A, Ewen M, Ross-Degnan D, Ball D, Laing R. Medicine prices, availability, and aff ordability in 36 developing and middle-income countries: a secondary analysis. Lancet. 2009;373:240–9.CrossRefPubMed
9.
go back to reference Dabare P, Wanigatunge C, Beneragama H. A national survey on availability, price and affordability of selected essential medicines for non communicable diseases in Sri Lanka. BMC Public Health. 2014;14:817.CrossRefPubMedPubMedCentral Dabare P, Wanigatunge C, Beneragama H. A national survey on availability, price and affordability of selected essential medicines for non communicable diseases in Sri Lanka. BMC Public Health. 2014;14:817.CrossRefPubMedPubMedCentral
10.
go back to reference Mendis S, Al-Bashir I, Dissanayake L, Varghese C, Fadhil I, Marhe E, et al. Gaps in capacity in primary care in low-resource settings for implementation of essential non communicable disease interventions. Int J Hypertens. 2012;10:1155. Mendis S, Al-Bashir I, Dissanayake L, Varghese C, Fadhil I, Marhe E, et al. Gaps in capacity in primary care in low-resource settings for implementation of essential non communicable disease interventions. Int J Hypertens. 2012;10:1155.
11.
go back to reference Kibirige D, Atuhe D, Sebunya R, Mwebaze R. Suboptimal glycaemic and blood pressure control and screening for diabetic complications in adult ambulatory diabetic patients in Uganda: a retrospective study from a developing country. J Diabetes Metab Disord. 2014;13:40.CrossRefPubMedPubMedCentral Kibirige D, Atuhe D, Sebunya R, Mwebaze R. Suboptimal glycaemic and blood pressure control and screening for diabetic complications in adult ambulatory diabetic patients in Uganda: a retrospective study from a developing country. J Diabetes Metab Disord. 2014;13:40.CrossRefPubMedPubMedCentral
14.
go back to reference Bahendeka S, Wesonga R, Mutungi G, Muwonge J, Neema S, Guwatudde D. Prevalence and correlates of diabetes mellitus in Uganda: a population-based national survey. Trop Med Int Health. 2016;21(3):405–16.CrossRefPubMed Bahendeka S, Wesonga R, Mutungi G, Muwonge J, Neema S, Guwatudde D. Prevalence and correlates of diabetes mellitus in Uganda: a population-based national survey. Trop Med Int Health. 2016;21(3):405–16.CrossRefPubMed
15.
go back to reference Guwatudde D, Mutungi G, Wesonga R, Kajjura R, Kasule H, Muwonge J, et al. The epidemiology of hypertension in Uganda: findings from the National non-communicable diseases risk factor survey. PLoS One. 2015;10(9):e0138991.CrossRefPubMedPubMedCentral Guwatudde D, Mutungi G, Wesonga R, Kajjura R, Kasule H, Muwonge J, et al. The epidemiology of hypertension in Uganda: findings from the National non-communicable diseases risk factor survey. PLoS One. 2015;10(9):e0138991.CrossRefPubMedPubMedCentral
16.
go back to reference Zhang W, Mondo C, Okello E, Musoke C, Kakande B, Nyakoojo W, et al. Presenting features of newly diagnosed rheumatic heart disease patients in Mulago Hospital: a pilot study. Cardiovasc J Afr. 2013;24(2):28–33.CrossRefPubMedPubMedCentral Zhang W, Mondo C, Okello E, Musoke C, Kakande B, Nyakoojo W, et al. Presenting features of newly diagnosed rheumatic heart disease patients in Mulago Hospital: a pilot study. Cardiovasc J Afr. 2013;24(2):28–33.CrossRefPubMedPubMedCentral
17.
go back to reference Lugero C, Kibirige D, Kayima J, Mondo C, Freers J. Atrial fibrillation among the black population in a Ugandan tertiary hospital. Int J Gen Med. 2016;9:191–8.CrossRefPubMedPubMedCentral Lugero C, Kibirige D, Kayima J, Mondo C, Freers J. Atrial fibrillation among the black population in a Ugandan tertiary hospital. Int J Gen Med. 2016;9:191–8.CrossRefPubMedPubMedCentral
18.
go back to reference Kuule J, Seremba E, Freers J. Anaemia among patients with congestive cardiac failure in Uganda – its impact on treatment outcomes. SAMJ. 2009;99(12):876–80.PubMed Kuule J, Seremba E, Freers J. Anaemia among patients with congestive cardiac failure in Uganda – its impact on treatment outcomes. SAMJ. 2009;99(12):876–80.PubMed
19.
go back to reference Katende D, Mutungi G, Baisley K, Biraro S, Ikoona E, Peck R, et al. Readiness of Ugandan health services for the management of outpatients with chronic diseases. Trop Med Int Health. 2015;20(10):1385–95.CrossRefPubMedPubMedCentral Katende D, Mutungi G, Baisley K, Biraro S, Ikoona E, Peck R, et al. Readiness of Ugandan health services for the management of outpatients with chronic diseases. Trop Med Int Health. 2015;20(10):1385–95.CrossRefPubMedPubMedCentral
24.
go back to reference WHO. AFRO Essential medicines price indicator: WHO model list, 2007 edition. 2007. WHO. AFRO Essential medicines price indicator: WHO model list, 2007 edition. 2007.
26.
go back to reference Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration withEACTS. Eur Heart J. 2016;37:2893–962.CrossRefPubMed Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration withEACTS. Eur Heart J. 2016;37:2893–962.CrossRefPubMed
27.
go back to reference Steg G, James S, Atar D, Badano L, Blomstrom-Lundqvist C, Borger M, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33:2569–619.CrossRefPubMed Steg G, James S, Atar D, Badano L, Blomstrom-Lundqvist C, Borger M, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33:2569–619.CrossRefPubMed
28.
go back to reference Roffi M, Patrono C, Collet J, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2016;37:267–315.CrossRefPubMed Roffi M, Patrono C, Collet J, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2016;37:267–315.CrossRefPubMed
29.
go back to reference Ponikowski P, Voors A, Anker S, Bueno H, Cleland J, Coats A, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016;37:2129–200.CrossRefPubMed Ponikowski P, Voors A, Anker S, Bueno H, Cleland J, Coats A, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016;37:2129–200.CrossRefPubMed
Metadata
Title
Access to medicines and diagnostic tests integral in the management of diabetes mellitus and cardiovascular diseases in Uganda: insights from the ACCODAD study
Authors
Davis Kibirige
David Atuhe
Leaticia Kampiire
Daniel Ssekikubo Kiggundu
Pamela Donggo
Juliet Nabbaale
Raymond Mbayo Mwebaze
Robert Kalyesubula
William Lumu
Publication date
01-12-2017
Publisher
BioMed Central
Published in
International Journal for Equity in Health / Issue 1/2017
Electronic ISSN: 1475-9276
DOI
https://doi.org/10.1186/s12939-017-0651-6

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