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Strahlentherapie und Onkologie
Published in: Strahlentherapie und Onkologie 1/2016

01-01-2016 | Literatur kommentiert

Abskopale Effekte der lokalen Radiotherapie in Kombination mit systemischer Immuntherapie bei Patienten mit metastasierten soliden Tumoren

Authors: Dr. Cédric Panje, Prof. Dr. Matthias Guckenberger

Published in: Strahlentherapie und Onkologie | Issue 1/2016

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Auszug

Abskopale Effekte im Sinne eines Tumoransprechens außerhalb des Bestrahlungsfelds bei Patienten mit metastasierten Malignomen gelten als immunvermittelte Reaktion, wurden jedoch bei alleiniger Radiotherapie nur äußerst selten beobachtet und bisher nicht systematisch untersucht. Die vorliegende Studie von Golden et al. ging erstmalig prospektiv der Häufigkeit abskopaler Effekte bei fokaler Radiotherapie in Kombination mit systemischer Applikation des Granulozyten-Makrophagen-Kolonie-stimulierenden Faktors (GM-CSF) nach, einem Aktivator der dendritischen Zellen [1]. …
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Metadata
Title
Abskopale Effekte der lokalen Radiotherapie in Kombination mit systemischer Immuntherapie bei Patienten mit metastasierten soliden Tumoren
Authors
Dr. Cédric Panje
Prof. Dr. Matthias Guckenberger
Publication date
01-01-2016
Publisher
Springer Berlin Heidelberg
Published in
Strahlentherapie und Onkologie / Issue 1/2016
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-015-0921-4

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