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World Journal of Emergency Surgery
Published in: World Journal of Emergency Surgery 1/2019

Open Access 01-12-2019 | Abdominal Surgery | Research article

Cost-effectiveness of the prevention of adhesions and adhesive small bowel obstruction after colorectal surgery with adhesion barriers: a modelling study

Authors: Pepijn Krielen, Janneke P. C. Grutters, Chema Strik, Richard P. G. ten Broek, Harry van Goor, Martijn W. J. Stommel

Published in: World Journal of Emergency Surgery | Issue 1/2019

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Abstract

Background

Adhesion barriers have proven to reduce adhesion-related complications in colorectal surgery. However, barriers are seldom applied. The aim of this study was to determine the cost-effectiveness of adhesion barriers in colorectal surgery.

Methods

A decision-tree model was developed to compare cost-effectiveness of no adhesion barrier with the use of an adhesion barrier in open and laparoscopic surgery. Outcomes were incidence of clinical consequences of adhesions, direct healthcare costs, and incremental cost-effectiveness ratio per adhesion prevented. Deterministic and probabilistic sensitivity analyses were performed.

Results

Adhesion barriers reduce adhesion incidence and incidence of adhesive small bowel obstruction in open and laparoscopic surgery. Adhesion barriers in open surgery reduce costs compared to no adhesion barrier ($4376 versus $4482). Using an adhesion barrier in laparoscopic procedures increases costs by $162 ($4482 versus $4320). The ICER in the laparoscopic cohort was $123. Probabilistic sensitivity analysis showed 66% and 41% probabilities of an adhesion barrier reducing costs for open and laparoscopic colorectal surgery, respectively.

Conclusion

The use of adhesion barriers in open colorectal surgery is cost-effective in preventing adhesion-related problems. In laparoscopic colorectal surgery, an adhesion barrier is effective at low costs.
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Metadata
Title
Cost-effectiveness of the prevention of adhesions and adhesive small bowel obstruction after colorectal surgery with adhesion barriers: a modelling study
Authors
Pepijn Krielen
Janneke P. C. Grutters
Chema Strik
Richard P. G. ten Broek
Harry van Goor
Martijn W. J. Stommel
Publication date
01-12-2019
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2019
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-019-0261-2

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