Skip to main content
Top
Published in: European Radiology 8/2012

01-08-2012 | Computed Tomography

Abdominal fat distribution on computed tomography predicts ureteric calculus fragmentation by shock wave lithotripsy

Authors: Hsu-Cheng Juan, Hung-Yu Lin, Yii-Her Chou, Yi-Hsin Yang, Paul Ming-Chen Shih, Shu-Mien Chuang, Jung-Tsung Shen, Yung-Shun Juan

Published in: European Radiology | Issue 8/2012

Login to get access

Abstract

Objectives

To assess the effects of abdominal fat on shock wave lithotripsy (SWL). We used pre-SWL unenhanced computed tomography (CT) to evaluate the impact of abdominal fat distribution and calculus characteristics on the outcome of SWL.

Methods

One hundred and eighty-five patients with a solitary ureteric calculus treated with SWL were retrospectively reviewed. Each patient underwent unenhanced CT within 1 month before SWL treatment. Treatment outcomes were evaluated 1 month later. Unenhanced CT parameters, including calculus surface area, Hounsfield unit (HU) density, abdominal fat area and skin to calculus distance (SSD) were analysed.

Results

One hundred and twenty-eight of the 185 patients were found to be calculus-free following treatment. HU density, total fat area, visceral fat area and SSD were identified as significant variables on multivariate logistic regression analysis. The receiver-operating characteristic analyses showed that total fat area, para/perirenal fat area and visceral fat area were sensitive predictors of SWL outcomes.

Conclusion

This study revealed that higher quantities of abdominal fat, especially visceral fat, are associated with a lower calculus-free rate following SWL treatment. Unenhanced CT is a convenient technique for diagnosing the presence of a calculus, assessing the intra-abdominal fat distribution and thereby helping to predict the outcome of SWL.

Key Points

Unenhanced CT is now widely used to assess ureteric calculi.
The same CT protocol can provide measurements of abdominal fat distribution.
Ureteric calculi are usually treated by shock wave lithotripsy (SWL).
Greater intra-abdominal fat stores are generally associated with poorer SWL results.
Literature
1.
go back to reference Abe T, Akakura K, Kawaguchi M et al (2005) Outcomes of shockwave lithotripsy for upper urinary-tract calculus: a large-scale study at a single institution. J Endourol 19:768–773PubMedCrossRef Abe T, Akakura K, Kawaguchi M et al (2005) Outcomes of shockwave lithotripsy for upper urinary-tract calculus: a large-scale study at a single institution. J Endourol 19:768–773PubMedCrossRef
2.
go back to reference Pareek G, Armenakas NA, Fracchia JA (2003) Hounsfield units on computerized tomography predict calculus-free rates after extracorporeal shock wave lithotripsy. J Urol 169:1679–1681PubMedCrossRef Pareek G, Armenakas NA, Fracchia JA (2003) Hounsfield units on computerized tomography predict calculus-free rates after extracorporeal shock wave lithotripsy. J Urol 169:1679–1681PubMedCrossRef
3.
go back to reference Srivastava A, Ahlawat R, Kumar A, Kapoor R, Bhandari M (1992) Management of impacted upper ureteric calculi: results of lithotripsy and percutaneous litholapaxy. Br J Urol 70:252–257 Srivastava A, Ahlawat R, Kumar A, Kapoor R, Bhandari M (1992) Management of impacted upper ureteric calculi: results of lithotripsy and percutaneous litholapaxy. Br J Urol 70:252–257
4.
go back to reference Juan YS, Huang CH, Wang CJ et al (2008) Predictive role of renal resistance indices in the extracorporeal shock-wave lithotripsy outcome of ureteric calculus. Scand J Urol Nephrol 42:364–368PubMedCrossRef Juan YS, Huang CH, Wang CJ et al (2008) Predictive role of renal resistance indices in the extracorporeal shock-wave lithotripsy outcome of ureteric calculus. Scand J Urol Nephrol 42:364–368PubMedCrossRef
5.
go back to reference Pearle MS, Watamull LM, Mullican MA (1999) Sensitivity of noncontrast helical computerized tomography and plain film radiography compared to flexible nephroscopy for detecting residual fragments after percutaneous nephrostolithotomy. J Urol 162:23–26PubMedCrossRef Pearle MS, Watamull LM, Mullican MA (1999) Sensitivity of noncontrast helical computerized tomography and plain film radiography compared to flexible nephroscopy for detecting residual fragments after percutaneous nephrostolithotomy. J Urol 162:23–26PubMedCrossRef
6.
go back to reference Olcott EW, Sommer FG, Napel S (1997) Accuracy of detection and measurement of renal calculi: in vitro comparison of three-dimensional spiral CT, radiography, and nephrotomography. Radiology 204:19–25PubMed Olcott EW, Sommer FG, Napel S (1997) Accuracy of detection and measurement of renal calculi: in vitro comparison of three-dimensional spiral CT, radiography, and nephrotomography. Radiology 204:19–25PubMed
7.
go back to reference Pareek G, Armenakas NA, Panagopoulos G, Bruno JJ, Fracchia JA (2005) Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. Urology 65:33–36PubMedCrossRef Pareek G, Armenakas NA, Panagopoulos G, Bruno JJ, Fracchia JA (2005) Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. Urology 65:33–36PubMedCrossRef
8.
go back to reference Mezentsev VA (2005) Extracorporeal shock wave lithotripsy in the treatment of renal pelvicalyceal stones in morbidly obese patients. Int Braz J Urol 31:105–110PubMedCrossRef Mezentsev VA (2005) Extracorporeal shock wave lithotripsy in the treatment of renal pelvicalyceal stones in morbidly obese patients. Int Braz J Urol 31:105–110PubMedCrossRef
9.
go back to reference Perks AE, Schuler TD, Lee J et al (2008) Stone attenuation and skin-to-stone distance on computed tomography predicts for stone fragmentation by shock wave lithotripsy. Urology 72:765–769PubMedCrossRef Perks AE, Schuler TD, Lee J et al (2008) Stone attenuation and skin-to-stone distance on computed tomography predicts for stone fragmentation by shock wave lithotripsy. Urology 72:765–769PubMedCrossRef
10.
go back to reference (2004) Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet, 363:157-163. (2004) Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet, 363:157-163.
11.
go back to reference Tokunaga K, Matsuzawa Y, Ishikawa K, Tarui S (1983) A novel technique for the determination of body fat by computed tomography. Int J Obes 7:437–445PubMed Tokunaga K, Matsuzawa Y, Ishikawa K, Tarui S (1983) A novel technique for the determination of body fat by computed tomography. Int J Obes 7:437–445PubMed
12.
go back to reference Dixon AK (1983) Abdominal fat assessed by computed tomography: sex difference in distribution. Clin Radiol 34:189–191PubMedCrossRef Dixon AK (1983) Abdominal fat assessed by computed tomography: sex difference in distribution. Clin Radiol 34:189–191PubMedCrossRef
13.
go back to reference Yoshizumi T, Nakamura T, Yamane M et al (1999) Abdominal fat: standardized technique for measurement at CT. Radiology 211:283–286PubMed Yoshizumi T, Nakamura T, Yamane M et al (1999) Abdominal fat: standardized technique for measurement at CT. Radiology 211:283–286PubMed
14.
go back to reference White W, Klein F (2006) Five-year clinical experience with the Dornier Delta lithotriptor. Urology 68:28–32PubMedCrossRef White W, Klein F (2006) Five-year clinical experience with the Dornier Delta lithotriptor. Urology 68:28–32PubMedCrossRef
16.
go back to reference Yilmaz S, Sindel T, Arslan G et al (1998) Renal colic: comparison of spiral CT, US and IVU in the detection of ureteric calculi. Eur Radiol 8:212–217PubMedCrossRef Yilmaz S, Sindel T, Arslan G et al (1998) Renal colic: comparison of spiral CT, US and IVU in the detection of ureteric calculi. Eur Radiol 8:212–217PubMedCrossRef
17.
go back to reference Graversen JA, Korets R, Hruby GW et al (2011) Evaluation of bioimpedance as novel predictor of extracorporeal shockwave lithotripsy success. J Endourol 25:1503-1506 Graversen JA, Korets R, Hruby GW et al (2011) Evaluation of bioimpedance as novel predictor of extracorporeal shockwave lithotripsy success. J Endourol 25:1503-1506
18.
go back to reference Kawasaki S, Aoki K, Hasegawa O et al (2008) Sonographic evaluation of visceral fat by measuring para- and perirenal fat. J Clin Ultrasound 36:129–133PubMedCrossRef Kawasaki S, Aoki K, Hasegawa O et al (2008) Sonographic evaluation of visceral fat by measuring para- and perirenal fat. J Clin Ultrasound 36:129–133PubMedCrossRef
19.
go back to reference El-Nahas AR, El-Assmy AM, Mansour O, Sheir KZ (2007) A prospective multivariate analysis of factors predicting calculus disintegration by extracorporeal shock wave lithotripsy: the value of high-resolution noncontrast computed tomography. Eur Urol 51:1688–1693PubMedCrossRef El-Nahas AR, El-Assmy AM, Mansour O, Sheir KZ (2007) A prospective multivariate analysis of factors predicting calculus disintegration by extracorporeal shock wave lithotripsy: the value of high-resolution noncontrast computed tomography. Eur Urol 51:1688–1693PubMedCrossRef
20.
go back to reference Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S (1987) Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 36:54–59PubMedCrossRef Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S (1987) Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 36:54–59PubMedCrossRef
21.
go back to reference Hyun YJ, Kim OY, Jang Y et al (2008) Evaluation of metabolic syndrome risk in Korean premenopausal women: not waist circumference but visceral fat. Circ J 72:1308–1315PubMedCrossRef Hyun YJ, Kim OY, Jang Y et al (2008) Evaluation of metabolic syndrome risk in Korean premenopausal women: not waist circumference but visceral fat. Circ J 72:1308–1315PubMedCrossRef
22.
go back to reference Hayashi T, Boyko EJ, McNeely MJ, Leonetti DL, Kahn SE, Fujimoto WY (2008) Visceral adiposity, not abdominal subcutaneous fat area, is associated with an increase in future insulin resistance in Japanese Americans. Diabetes 57:1269–1275PubMedCrossRef Hayashi T, Boyko EJ, McNeely MJ, Leonetti DL, Kahn SE, Fujimoto WY (2008) Visceral adiposity, not abdominal subcutaneous fat area, is associated with an increase in future insulin resistance in Japanese Americans. Diabetes 57:1269–1275PubMedCrossRef
23.
go back to reference Oka R, Miura K, Sakurai M et al (2010) Impacts of visceral adipose tissue and subcutaneous adipose tissue on metabolic risk factors in middle-aged Japanese. Obesity (Silver Spring) 18:153-160 Oka R, Miura K, Sakurai M et al (2010) Impacts of visceral adipose tissue and subcutaneous adipose tissue on metabolic risk factors in middle-aged Japanese. Obesity (Silver Spring) 18:153-160
24.
go back to reference Eguchi M, Tsuchihashi K, Saitoh S et al (2007) Visceral obesity in Japanese patients with metabolic syndrome: reappraisal of diagnostic criteria by CT scan. Hypertens Res 30:315–323PubMedCrossRef Eguchi M, Tsuchihashi K, Saitoh S et al (2007) Visceral obesity in Japanese patients with metabolic syndrome: reappraisal of diagnostic criteria by CT scan. Hypertens Res 30:315–323PubMedCrossRef
25.
go back to reference Pareek G, Hedican SP, Lee FT Jr, Nakada SY (2005) Shock wave lithotripsy success determined by skin-to-calculus distance on computed tomography. Urology 66:941–944PubMedCrossRef Pareek G, Hedican SP, Lee FT Jr, Nakada SY (2005) Shock wave lithotripsy success determined by skin-to-calculus distance on computed tomography. Urology 66:941–944PubMedCrossRef
26.
go back to reference Chou YH, Su CM, Li CC et al (2011) Difference in urinary stone components between obese and non-obese patients. Urol Res 39:283–287PubMedCrossRef Chou YH, Su CM, Li CC et al (2011) Difference in urinary stone components between obese and non-obese patients. Urol Res 39:283–287PubMedCrossRef
27.
go back to reference Williams JC Jr, Saw KC, Paterson RF, Hatt EK, McAteer JA, Lingeman JE (2003) Variability of renal stone fragility in shock wave lithotripsy. Urology 61:1092–1096PubMedCrossRef Williams JC Jr, Saw KC, Paterson RF, Hatt EK, McAteer JA, Lingeman JE (2003) Variability of renal stone fragility in shock wave lithotripsy. Urology 61:1092–1096PubMedCrossRef
28.
go back to reference Seitz C, Tanovic E, Kikic Z, Memarsadeghi M, Fajkovic H (2007) Rapid extracorporeal shock wave lithotripsy for proximal ureteral calculi in colic versus noncolic patients. Eur Urol 52:1223–1227PubMedCrossRef Seitz C, Tanovic E, Kikic Z, Memarsadeghi M, Fajkovic H (2007) Rapid extracorporeal shock wave lithotripsy for proximal ureteral calculi in colic versus noncolic patients. Eur Urol 52:1223–1227PubMedCrossRef
Metadata
Title
Abdominal fat distribution on computed tomography predicts ureteric calculus fragmentation by shock wave lithotripsy
Authors
Hsu-Cheng Juan
Hung-Yu Lin
Yii-Her Chou
Yi-Hsin Yang
Paul Ming-Chen Shih
Shu-Mien Chuang
Jung-Tsung Shen
Yung-Shun Juan
Publication date
01-08-2012
Publisher
Springer-Verlag
Published in
European Radiology / Issue 8/2012
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-012-2413-6

Other articles of this Issue 8/2012

European Radiology 8/2012 Go to the issue