Top

Child's Nervous System

Published in:

01-05-2016 | Case Report

A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review

Authors: Loic Sigwalt, Emeline Bourgeois, Ahmad Eid, Chantal Durand, Jacques Griffet, Aurélien Courvoisier

Published in: Child's Nervous System | Issue 5/2016

Abstract

Purpose

Giant cell tumors (GCT) are benign primary bone tumors, locally aggressive, affecting in long bones in young adults during the third decade. It is rare to experience this lesion in skeletally immature patients. GCT are related to a risk of local recurrence and malignant transformation.

Method

We report a rare case of a giant cell tumor of the thoracic spine in a skeletally immature girl presenting with a painful right scoliosis.

Results

MRI, CT scan, and bone scintigraphy were discordant and the percutaneous biopsy non-contributive.

Conclusion

A marginal “en bloc” resection was performed and revealed the GCT. Based on a literature review, the diagnosis and the surgical management of this case are discussed.

Mira J (1980) Bone tumors: diagnosis and treatment. Philadelphia

Enneking W (1983) Musculoskeletal tumor surgery. Churchill Livingstone, Philadelphia

Boriani S, Bandiera S, Casadei R, Boriani L, Donthineni R, Gasbarrini A, Pignotti E, Biagini R, Schwab JH (2012) Giant cell tumor of the mobile spine: a review of 49 cases. Spine (Phila Pa 1976) 37(1):E37–E45. doi:10.1097/BRS.0b013e3182233ccd CrossRef

Miller G, Bettelli G, Fabbri N, Capanna R (1990) Curettage of giant cell tumor of bone. Introduction—material and methods. Chir Organi Mov 75(1 Suppl):203PubMed

Unni K (1998) Dahlin’s bone tumors: general aspects and data on 11087 cases. Lippincott-Raven, Philadelphia

Dahlin DC, Cupps RE, Johnson EW Jr (1970) Giant-cell tumor: a study of 195 cases. Cancer 25(5):1061–1070CrossRefPubMed

Campanacci M, Baldini N, Boriani S, Sudanese A (1987) Giant-cell tumor of bone. J Bone Joint Surg Am 69(1):106–114PubMed

Larsson SE, Lorentzon R, Boquist L (1975) Giant-cell tumor of bone. A demographic, clinical, and histopathological study of all cases recorded in the Swedish Cancer Registry for the years 1958 through 1968. J Bone Joint Surg Am 57(2):167–173PubMed

Turcotte RE, Biagini R, Sim FH, Unni KK (1990) Giant cell tumor of the spine and sacrum. Chir Organi Mov 75(1 Suppl):104–107PubMed

10.

Metkar U, Wardak Z, Katz DA, Lavelle WF (2012) Giant cell tumor of a lumbar vertebra in a 7-year-old child: a case report. J Pediatr Orthop 32(8):e76–e80. doi:10.1097/BPO.0b013e31826193e7 CrossRefPubMed

11.

Wu KK, Ross PM, Mitchell DC, Sprague HH (1986) Evolution of a case of multicentric giant cell tumor over a 23-year period. Clin Orthop Relat Res 213:279–288PubMed

12.

Hart RA, Boriani S, Biagini R, Currier B, Weinstein JN (1997) A system for surgical staging and management of spine tumors. A clinical outcome study of giant cell tumors of the spine. Spine (Phila Pa 1976) 22(15):1773–1782, discussion 1783CrossRef

13.

Si MJ, Wang CG, Wang CS, Du LJ, Ding XY, Zhang WB, Lu Y, Zu JY (2014) Giant cell tumours of the mobile spine: characteristic imaging features and differential diagnosis. Radiol Med 119(9):681–693. doi:10.1007/s11547-013-0352-1 CrossRefPubMed

14.

Martin C, McCarthy EF (2010) Giant cell tumor of the sacrum and spine: series of 23 cases and a review of the literature. Iowa Orthop J 30:69–75PubMedPubMedCentral

15.

Campanacci M (1990) Giant-cell tumor. In: Gaggi (ed) Bone and soft-tissue tumors. Springer, Bologna, pp 117–153CrossRef

16.

Feigenberg SJ, Marcus RB Jr, Zlotecki RA, Scarborough MT, Berrey BH, Enneking WF (2003) Radiation therapy for giant cell tumors of bone. Clin Orthop Relat Res 411:207–216. doi:10.1097/01.blo.0000069890.31220.b4 CrossRefPubMed

Title: A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review
Authors: Loic Sigwalt
Emeline Bourgeois
Ahmad Eid
Chantal Durand
Jacques Griffet
Aurélien Courvoisier
Publication date: 01-05-2016
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 5/2016
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-015-2991-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review

Abstract

Purpose

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Method

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 5/2016

Multiple encephalogaleoperiosteal synangiosis for bilateral carotid artery stenosis in a 13-year-old girl: a case report

Posterior reversible encephalopathy syndrome (PRES): a rare condition after resection of posterior fossa tumors: two new cases and review of the literature

Functional outcomes of infants with Narakas grade 1 birth-related brachial plexus palsy undergoing neurotization compared with infants who did not require surgery

Congenital subaxial cervical subluxation presenting as a bilateral Erb’s palsy: surgical management, rehabilitation, and outcome

25th Congress of the European Society for Pediatric Neurosurgery (ESPN) Paris-France, 8-11 May 2016

Solitary Langerhans cell histiocytosis located in the neurohypophysis with a positive titer HCG-β in the cerebrospinal fluid