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Clinical Oral Investigations
Published in: Clinical Oral Investigations 8/2013

01-11-2013 | Review

A systematic review on the outcome of mandibular distraction osteogenesis in infants suffering Robin sequence

Authors: Emma C. Paes, Aebele B. Mink van der Molen, Marvick S. M. Muradin, Lucienne Speleman, Frea Sloot, Moshe Kon, Corstiaan C. Breugem

Published in: Clinical Oral Investigations | Issue 8/2013

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Abstract

Objectives

Mandibular distraction osteogenesis (MDO) has been successfully applied in infants suffering Robin sequence (RS) with severe upper airway obstruction, but no comparative studies for the different types of MDO exist to date. The objective of the current study was to systematically review the published data considering this matter, providing a fundament for protocols and a more conscious treatment strategy for infants with RS in the near future.

Material and methods

For the period from January 1966 to January 2012, the Pubmed, EMBASE, and Cochrane Library databases were searched. Abstracts were screened based on predetermined selection criteria. Relevant full-text articles were retrieved. The articles were analyzed on the type of MDO used, preoperative workup, patient characteristics, postoperative outcome, and complications.

Results

The search yielded 109 articles. After checking abstracts and full texts on predetermined inclusion and exclusion criteria, 12 studies (four describing external MDO, five internal MDO, and three both types) were extracted for further analyses.

Conclusion

Internal MDO seems very feasible in infants suffering RS, minimizing side effects such as hypertrophic scarring, nerve damage, and extensive care needs, although the indications for usage are more limited compared to the external device. Corresponding protocols and long-term outcome studies are needed to make a better comparison and the use and indication of the different types of distraction even more distinct.

Clinical relevance

A base for a guideline to support the choice of a designated operative management for neonates with RS is provided, hereby obviating possible complications of the different types of MDO in the future.
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Metadata
Title
A systematic review on the outcome of mandibular distraction osteogenesis in infants suffering Robin sequence
Authors
Emma C. Paes
Aebele B. Mink van der Molen
Marvick S. M. Muradin
Lucienne Speleman
Frea Sloot
Moshe Kon
Corstiaan C. Breugem
Publication date
01-11-2013
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 8/2013
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-013-0998-z

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