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International Urogynecology Journal

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01-08-2012 | Review Article

A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction

Authors: Ash K. Monga, Michael R. Tracey, Jeyakumar Subbaroyan

Published in: International Urogynecology Journal | Issue 8/2012

Abstract

Introduction and hypothesis

The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).

Methods

The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.

Results

Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.

Conclusions

Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies.

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Title: A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction
Authors: Ash K. Monga
Michael R. Tracey
Jeyakumar Subbaroyan
Publication date: 01-08-2012
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 8/2012
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-012-1691-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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