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European Journal of Nuclear Medicine and Molecular Imaging
Published in: European Journal of Nuclear Medicine and Molecular Imaging 4/2003

01-04-2003 | Short Communication

A study of the acute effect of smoking on cerebral blood flow using 99mTc-ECD SPET

Authors: Yuka Yamamoto, Yoshihiro Nishiyama, Toshihide Monden, Katashi Satoh, Motoomi Ohkawa

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 4/2003

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Abstract

Cigarette smoking is known to be associated with atherosclerosis, is an important risk factor for stroke and has other serious effects. The aim of this study was to evaluate the acute effect of cigarette smoking on cerebral blood flow using statistical parametric mapping (SPM). Ten healthy volunteers with a smoking habit were studied using technetium-99m-labelled ethylcysteinate dimer single-photon emission tomography (SPET). We evaluated the regional cerebral blood flow under the smoking and resting states. The regional cerebral blood flow on smoking-activated SPET was significantly decreased in the whole brain as compared with that on resting SPET. Our findings therefore suggest that one of the acute effects of cigarette smoking is to induce a diffuse decrease in cerebral blood flow.
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Metadata
Title
A study of the acute effect of smoking on cerebral blood flow using 99mTc-ECD SPET
Authors
Yuka Yamamoto
Yoshihiro Nishiyama
Toshihide Monden
Katashi Satoh
Motoomi Ohkawa
Publication date
01-04-2003
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 4/2003
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-003-1119-z

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