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Open Access 01-12-2022 | Protocol

A scoping review protocol on in vivo human plastic exposure and health impacts

Authors: Louise M. Goodes, Enoch V. S. Wong, Jennifer Alex, Louise Mofflin, Priyanka Toshniwal, Manuel Brunner, Terena Solomons, Emily White, Omrik Choudhury, Bhedita J. Seewoo, Yannick R. Mulders, Tristan Dale, Hamish J. Newman, Alina Naveed, Andrew B. Lowe, Delia V. Hendrie, Christos Symeonides, Sarah A. Dunlop

Published in: Systematic Reviews | Issue 1/2022

Abstract

Background

Global plastic production has increased exponentially since the 1960s, with more than 6300 million metric tons of plastic waste generated to date. Studies have found a range of human health outcomes associated with exposure to plastic chemicals. However, only a fraction of plastic chemicals used have been studied in vivo, and then often in animals, for acute toxicological effects. With many questions still unanswered about how long-term exposure to plastic impacts human health, there is an urgent need to map human in vivo research conducted to date, casting a broad net by searching terms for a comprehensive suite of plastic chemical exposures and the widest range of health domains.

Methods

This protocol describes a scoping review that will follow the recommended framework outlined in the 2017 Guidance for the Conduct of Joanna Briggs Institute (JBI) Scoping Reviews, to be reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist. A literature search of primary clinical studies in English from 1960 onwards will be conducted in MEDLINE (Ovid) and EMBASE (Ovid) databases. References eligible for inclusion will be identified through a quality-controlled, multi-level screening process. Extracted data will be presented in diagrammatic and tabular form, with a narrative summary addressing the review questions.

Discussion

This scoping review will comprehensively map the primary research undertaken to date on plastic exposure and human health. Secondary outputs will include extensive databases on plastic chemicals and human health outcomes/impacts.

Systematic review registration

Open Science Framework (OSF)-Standard Pre-Data Collection Registration, https://archive.org/details/osf-registrations-gbxps-v1, https://doi.org/10.17605/OSF.IO/GBXPS

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Title: A scoping review protocol on in vivo human plastic exposure and health impacts
Authors: Louise M. Goodes
Enoch V. S. Wong
Jennifer Alex
Louise Mofflin
Priyanka Toshniwal
Manuel Brunner
Terena Solomons
Emily White
Omrik Choudhury
Bhedita J. Seewoo
Yannick R. Mulders
Tristan Dale
Hamish J. Newman
Alina Naveed
Andrew B. Lowe
Delia V. Hendrie
Christos Symeonides
Sarah A. Dunlop
Publication date: 01-12-2022
Publisher: BioMed Central
Published in: Systematic Reviews / Issue 1/2022
Electronic ISSN: 2046-4053
DOI: https://doi.org/10.1186/s13643-022-02010-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A scoping review protocol on in vivo human plastic exposure and health impacts

Abstract

Background

Methods

Discussion

Systematic review registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Discussion

Systematic review registration

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