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01-08-2016 | Review

A review of the literature for intra-arterial chemotherapy used to treat retinoblastoma

Authors: Emily Wyse, James T. Handa, Alan D. Friedman, Monica S. Pearl

Published in: Pediatric Radiology | Issue 9/2016

Abstract

Retinoblastoma is a malignancy of the retina that usually presents before the age of 5 years. Sporadic retinoblastoma is most often unilateral and with no hereditary influence, whereas familial retinoblastoma presents unilaterally or bilaterally in conjunction with genetic inheritance. Several treatments have been attempted with the goals of saving the child’s life, salvaging the eye, and preserving vision. Alternative methods including external beam radiation, systemic chemotherapy and focal therapies have been shown to be effective but carry a risk of enucleation and other complications proportional to the severity of the tumor. Selective intra-arterial chemotherapy for retinoblastoma began in 1988 in Japan and has emerged in the last 7 years in the United States as a feasible, effective and minimally invasive treatment option. We review the retinoblastoma treatment literature focusing on intra-arterial chemotherapy.

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Title: A review of the literature for intra-arterial chemotherapy used to treat retinoblastoma
Authors: Emily Wyse
James T. Handa
Alan D. Friedman
Monica S. Pearl
Publication date: 01-08-2016
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 9/2016
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-016-3554-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A review of the literature for intra-arterial chemotherapy used to treat retinoblastoma

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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