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01-01-2019 | Mini-review

A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff

Authors: Lu-Jing Lei, Wen-Le Wang, Jie Wang, Li-juan Lv, Min-Hui Li

Published in: Journal of Natural Medicines | Issue 1/2019

Abstract

Changium smyrnioides Wolff is a monotypic species of the genus Changium Wolff which is only found in eastern China. C. smyrnioides has been used as a traditional medicine for ages to treat cough, vomiting, nausea, megrim, and carbuncle. It is also widely used to brew medicated liquor and health tea with other herbs in order to moisten the lungs and nourish blood and yin. This review comprehensively summarizes the up-to-date information on the botanical characterization, distribution, traditional uses, ethnopharmacology, phytochemistry, pharmacology, and toxicity of C. smyrnioides based on studies published in recent years. Phytochemical investigations have revealed that phenylpropanoids, volatile oils, fatty acids, phytosterols, and other bioactive compounds are contained in C. smyrnioides. Crude extracts and monomeric compounds isolated from C. smyrnioides have significant effects on the respiratory, immune, and vascular systems and exhibit favourable activities such as antitussive, eliminating phlegm, anti-asthmatic, immunoregulatory, antioxidant, anti-tumor, anti-fatigue, anti-hypoxia, and anti-atherosclerotic effects. C. smyrnioides is a promising medicinal herb with immense therapeutic and health-promoting effects. Therefore, further studies on the bioactive compounds and mechanisms of C. smyrnioides are necessary. Additional clinical and toxicological studies are warranted to evaluate its safety.

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Title: A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff
Authors: Lu-Jing Lei
Wen-Le Wang
Jie Wang
Li-juan Lv
Min-Hui Li
Publication date: 01-01-2019
Publisher: Springer Singapore
Published in: Journal of Natural Medicines / Issue 1/2019
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-018-1245-3

At a glance: The STEP trials

Springer Medicine

A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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