Skip to main content
Top
Published in: European Spine Journal 5/2018

01-05-2018 | Review

A review of lumbosacral transitional vertebrae and associated vertebral numeration

Authors: Jayson Lian, Nicole Levine, Woojin Cho

Published in: European Spine Journal | Issue 5/2018

Login to get access

Abstract

Purpose

To review the current literature on methods of accurate numeration of vertebral segments in patients with Lumbosacral transitional vertebrae (LSTVs). LSTVs are a common congenital anomaly of the L5–S1 junction. While their clinical significance has been debated, unquestionable is the need for their identification prior to spinal surgery. We hypothesize that there are no reliable landmarks by which we can accurately number transitional vertebrae, and thus a full spinal radiograph is required.

Methods

A Pubmed and EMBASE search using various combinations of specific key words including “LSTV”, “lumbosacral transitional vertebrae”, “count”, “vertebral numbering”, and “number” was performed.

Results

The gold standard for spinal segment numeration in patients with LSTV remains whole spine imaging and counting caudally, starting from C2. If whole spine imaging is not available, the use of the iliac crest tangent sign on coronal magnetic resonance imaging (MRI) has fairly reliable sensitivity and specificity (81 and 64–88%, respectively) for accurate numeration of LSTV. The role of paraspinal anatomic markers such as the right renal artery, superior mesenteric artery, aortic bifurcation, and conus medullaris, for identification of vertebral levels is unreliable and should not be used.

Conclusions

A sagittal whole spine view should be added as a scout view when patients obtain lumbar MRI to standardize the vertebral numbering technique. To date, there has been no other method for accurate numeration of a transitional vertebral segment, other than counting caudally from C2.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.
Appendix
Available only for authorised users
Literature
1.
go back to reference Konin GP, Walz DM (2010) Lumbosacral transitional vertebrae: classification, imaging findings, and clinical relevance. AJNR Am J Neuroradiol 31(10):1778–1786CrossRefPubMed Konin GP, Walz DM (2010) Lumbosacral transitional vertebrae: classification, imaging findings, and clinical relevance. AJNR Am J Neuroradiol 31(10):1778–1786CrossRefPubMed
2.
go back to reference Apazidis A et al (2011) The prevalence of transitional vertebrae in the lumbar spine. Spine J 11(9):858–862CrossRefPubMed Apazidis A et al (2011) The prevalence of transitional vertebrae in the lumbar spine. Spine J 11(9):858–862CrossRefPubMed
3.
4.
go back to reference Quinlan JF, Duke D, Eustace S (2006) Bertolotti’s syndrome. A cause of back pain in young people. J Bone Jt Surg Br 88(9):1183–1186CrossRef Quinlan JF, Duke D, Eustace S (2006) Bertolotti’s syndrome. A cause of back pain in young people. J Bone Jt Surg Br 88(9):1183–1186CrossRef
5.
go back to reference Mody MG et al (2008) The prevalence of wrong level surgery among spine surgeons. Spine (Phila Pa 1976) 33(2):194–198CrossRef Mody MG et al (2008) The prevalence of wrong level surgery among spine surgeons. Spine (Phila Pa 1976) 33(2):194–198CrossRef
6.
go back to reference Tini PG, Wieser C, Zinn WM (1977) The transitional vertebra of the lumbosacral spine: its radiological classification, incidence, prevalence, and clinical significance. Rheumatol Rehabil 16(3):180–185CrossRefPubMed Tini PG, Wieser C, Zinn WM (1977) The transitional vertebra of the lumbosacral spine: its radiological classification, incidence, prevalence, and clinical significance. Rheumatol Rehabil 16(3):180–185CrossRefPubMed
8.
go back to reference Wellik DM, Capecchi MR (2003) Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science 301(5631):363–367CrossRefPubMed Wellik DM, Capecchi MR (2003) Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science 301(5631):363–367CrossRefPubMed
10.
go back to reference Peleg S et al (2007) Orientation of the human sacrum: anthropological perspectives and methodological approaches. Am J Phys Anthropol 133(3):967–977CrossRefPubMed Peleg S et al (2007) Orientation of the human sacrum: anthropological perspectives and methodological approaches. Am J Phys Anthropol 133(3):967–977CrossRefPubMed
11.
go back to reference Mahato NK (2010) Morphological traits in sacra associated with complete and partial lumbarization of first sacral segment. Spine J 10(10):910–915CrossRefPubMed Mahato NK (2010) Morphological traits in sacra associated with complete and partial lumbarization of first sacral segment. Spine J 10(10):910–915CrossRefPubMed
12.
go back to reference Aihara T et al (2005) Intervertebral disc degeneration associated with lumbosacral transitional vertebrae: a clinical and anatomical study. J Bone Jt Surg Br 87(5):687–691CrossRef Aihara T et al (2005) Intervertebral disc degeneration associated with lumbosacral transitional vertebrae: a clinical and anatomical study. J Bone Jt Surg Br 87(5):687–691CrossRef
13.
go back to reference Castellvi AE, Goldstein LA, Chan DP (1984) Lumbosacral transitional vertebrae and their relationship with lumbar extradural defects. Spine 9(5):493–495CrossRefPubMed Castellvi AE, Goldstein LA, Chan DP (1984) Lumbosacral transitional vertebrae and their relationship with lumbar extradural defects. Spine 9(5):493–495CrossRefPubMed
14.
go back to reference O’Driscoll CM, Irwin A, Saifuddin A (1996) Variations in morphology of the lumbosacral junction on sagittal MRI: correlation with plain radiography. Skelet Radiol 25(3):225–230CrossRef O’Driscoll CM, Irwin A, Saifuddin A (1996) Variations in morphology of the lumbosacral junction on sagittal MRI: correlation with plain radiography. Skelet Radiol 25(3):225–230CrossRef
15.
go back to reference Bertolotti M (1917) Contributo alla conoscenze dei vizi di differenzazione regionale del rachide con speciale riguardo alla assimilazione sacrale della V. lombrare. Radiologique Medica (Torino) 4:113–144 Bertolotti M (1917) Contributo alla conoscenze dei vizi di differenzazione regionale del rachide con speciale riguardo alla assimilazione sacrale della V. lombrare. Radiologique Medica (Torino) 4:113–144
16.
go back to reference Luoma K et al (2004) Lumbosacral transitional vertebra: relation to disc degeneration and low back pain. Spine (Phila Pa 1976) 29(2):200–205CrossRef Luoma K et al (2004) Lumbosacral transitional vertebra: relation to disc degeneration and low back pain. Spine (Phila Pa 1976) 29(2):200–205CrossRef
17.
go back to reference Lee CS et al (2015) The clinical importance of lumbosacral transitional vertebra in patients with adolescent idiopathic scoliosis. Spine 40(17):E964–E970CrossRefPubMed Lee CS et al (2015) The clinical importance of lumbosacral transitional vertebra in patients with adolescent idiopathic scoliosis. Spine 40(17):E964–E970CrossRefPubMed
18.
go back to reference Gay RE et al (2006) Sagittal plane motion in the human lumbar spine: comparison of the in vitro quasistatic neutral zone and dynamic motion parameters. Clin Biomech (Bristol Avon) 21(9):914–919CrossRef Gay RE et al (2006) Sagittal plane motion in the human lumbar spine: comparison of the in vitro quasistatic neutral zone and dynamic motion parameters. Clin Biomech (Bristol Avon) 21(9):914–919CrossRef
19.
go back to reference Vergauwen S et al (1997) Distribution and incidence of degenerative spine changes in patients with a lumbo-sacral transitional vertebra. Eur Spine J 6(3):168–172CrossRefPubMedPubMedCentral Vergauwen S et al (1997) Distribution and incidence of degenerative spine changes in patients with a lumbo-sacral transitional vertebra. Eur Spine J 6(3):168–172CrossRefPubMedPubMedCentral
20.
go back to reference Ahn SS et al (2017) The clinical significance of lumbosacral transitional vertebrae on the surgical outcomes of lumbar discectomy: a retrospective cohort study of young adults. World Neurosurg 99:745–750CrossRefPubMed Ahn SS et al (2017) The clinical significance of lumbosacral transitional vertebrae on the surgical outcomes of lumbar discectomy: a retrospective cohort study of young adults. World Neurosurg 99:745–750CrossRefPubMed
21.
go back to reference Hughes RJ, Saifuddin A (2004) Imaging of lumbosacral transitional vertebrae. Clin Radiol 59(11):984–991CrossRefPubMed Hughes RJ, Saifuddin A (2004) Imaging of lumbosacral transitional vertebrae. Clin Radiol 59(11):984–991CrossRefPubMed
22.
go back to reference Taskaynatan MA et al (2005) Clinical significance of congenital lumbosacral malformations in young male population with prolonged low back pain. Spine (Phila Pa 1976) 30(8):E210–E213CrossRef Taskaynatan MA et al (2005) Clinical significance of congenital lumbosacral malformations in young male population with prolonged low back pain. Spine (Phila Pa 1976) 30(8):E210–E213CrossRef
23.
go back to reference Illeez OG et al (2018) The transitional vertebra and sacroiliac joint dysfunction association. Eur Spine J 27:187–193CrossRefPubMed Illeez OG et al (2018) The transitional vertebra and sacroiliac joint dysfunction association. Eur Spine J 27:187–193CrossRefPubMed
24.
go back to reference Shibayama M et al (2011) Unsuspected reason for sciatica in Bertolotti’s syndrome. J Bone Jt Surg Br 93(5):705–707CrossRef Shibayama M et al (2011) Unsuspected reason for sciatica in Bertolotti’s syndrome. J Bone Jt Surg Br 93(5):705–707CrossRef
25.
go back to reference Mahato NK (2011) Disc spaces, vertebral dimensions, and angle values at the lumbar region: a radioanatomical perspective in spines with L5–S1 transitions: clinical article. J Neurosurg Spine 15(4):371–379CrossRefPubMed Mahato NK (2011) Disc spaces, vertebral dimensions, and angle values at the lumbar region: a radioanatomical perspective in spines with L5–S1 transitions: clinical article. J Neurosurg Spine 15(4):371–379CrossRefPubMed
26.
go back to reference Josiah DT et al (2017) Anatomical differences in patients with lumbosacral transitional vertebrae and implications for minimally invasive spine surgery. J Neurosurg Spine 26(2):137–143CrossRefPubMed Josiah DT et al (2017) Anatomical differences in patients with lumbosacral transitional vertebrae and implications for minimally invasive spine surgery. J Neurosurg Spine 26(2):137–143CrossRefPubMed
27.
go back to reference Benlidayi IC, Coskun NC, Basaran S (2015) Does lumbosacral transitional vertebra have any influence on sacral tilt? Spine (Phila Pa 1976) 40(22):E1176–E1179CrossRef Benlidayi IC, Coskun NC, Basaran S (2015) Does lumbosacral transitional vertebra have any influence on sacral tilt? Spine (Phila Pa 1976) 40(22):E1176–E1179CrossRef
28.
go back to reference Crawford CH 3rd et al (2017) Conflicting calculations of pelvic incidence and pelvic tilt secondary to transitional lumbosacral anatomy (lumbarization of S-1): case report. J Neurosurg Spine 26(1):45–49CrossRefPubMed Crawford CH 3rd et al (2017) Conflicting calculations of pelvic incidence and pelvic tilt secondary to transitional lumbosacral anatomy (lumbarization of S-1): case report. J Neurosurg Spine 26(1):45–49CrossRefPubMed
29.
go back to reference O’Brien MF, Kiklo T, Blanke KM, Lenke LG, Spinal Deformity Study Group (SDSG) (Editors in Chief) (2008) Radiographic measurement manual. Medtronic Sofamor Danek USA, Inc., Memphis O’Brien MF, Kiklo T, Blanke KM, Lenke LG, Spinal Deformity Study Group (SDSG) (Editors in Chief) (2008) Radiographic measurement manual. Medtronic Sofamor Danek USA, Inc., Memphis
30.
31.
go back to reference Tureli D, Ekinci G, Baltacioglu F (2014) Is any landmark reliable in vertebral enumeration? A study of 3.0-Tesla lumbar MRI comparing skeletal, neural, and vascular markers. Clin Imaging 38(6):792–796CrossRefPubMed Tureli D, Ekinci G, Baltacioglu F (2014) Is any landmark reliable in vertebral enumeration? A study of 3.0-Tesla lumbar MRI comparing skeletal, neural, and vascular markers. Clin Imaging 38(6):792–796CrossRefPubMed
32.
go back to reference Furman MB, Wahlberg B, Cruz EJ (2018) Lumbosacral transitional segments: an interventional spine specialist’s practical approach. Phys Med Rehabil Clin N Am 29(1):35–48CrossRefPubMed Furman MB, Wahlberg B, Cruz EJ (2018) Lumbosacral transitional segments: an interventional spine specialist’s practical approach. Phys Med Rehabil Clin N Am 29(1):35–48CrossRefPubMed
33.
go back to reference Tokgoz N et al (2014) Are spinal or paraspinal anatomic markers helpful for vertebral numbering and diagnosing lumbosacral transitional vertebrae? Korean J Radiol 15(2):258–266CrossRefPubMedPubMedCentral Tokgoz N et al (2014) Are spinal or paraspinal anatomic markers helpful for vertebral numbering and diagnosing lumbosacral transitional vertebrae? Korean J Radiol 15(2):258–266CrossRefPubMedPubMedCentral
34.
go back to reference Hahn PY, Strobel JJ, Hahn FJ (1992) Verification of lumbosacral segments on MR images: identification of transitional vertebrae. Radiology 182(2):580–581CrossRefPubMed Hahn PY, Strobel JJ, Hahn FJ (1992) Verification of lumbosacral segments on MR images: identification of transitional vertebrae. Radiology 182(2):580–581CrossRefPubMed
35.
go back to reference Peh WC, Siu TH, Chan JH (1999) Determining the lumbar vertebral segments on magnetic resonance imaging. Spine (Phila Pa 1976) 24(17):1852–1855CrossRef Peh WC, Siu TH, Chan JH (1999) Determining the lumbar vertebral segments on magnetic resonance imaging. Spine (Phila Pa 1976) 24(17):1852–1855CrossRef
36.
go back to reference Tins B et al (1016) Three-dimensional sampling perfection with application-optimised contrasts using a different flip angle evolutions sequence for routine imaging of the spine: preliminary experience. Br J Radiol 2012(85):e480–e489 Tins B et al (1016) Three-dimensional sampling perfection with application-optimised contrasts using a different flip angle evolutions sequence for routine imaging of the spine: preliminary experience. Br J Radiol 2012(85):e480–e489
37.
go back to reference Bressler EL (2007) Numbering of lumbosacral transitional vertebrae on MRI. AJR Am J Roentgenol 188(2):W210 (author reply W211) CrossRefPubMed Bressler EL (2007) Numbering of lumbosacral transitional vertebrae on MRI. AJR Am J Roentgenol 188(2):W210 (author reply W211) CrossRefPubMed
38.
go back to reference Carrino JA et al (2011) Effect of spinal segment variants on numbering vertebral levels at lumbar MR imaging. Radiology 259(1):196–202CrossRefPubMed Carrino JA et al (2011) Effect of spinal segment variants on numbering vertebral levels at lumbar MR imaging. Radiology 259(1):196–202CrossRefPubMed
39.
go back to reference Farshad-Amacker NA et al (2014) Is the iliolumbar ligament a reliable identifier of the L5 vertebra in lumbosacral transitional anomalies? Eur Radiol 24(10):2623–2630CrossRefPubMed Farshad-Amacker NA et al (2014) Is the iliolumbar ligament a reliable identifier of the L5 vertebra in lumbosacral transitional anomalies? Eur Radiol 24(10):2623–2630CrossRefPubMed
40.
go back to reference Lee CH et al (2004) Using MRI to evaluate anatomic significance of aortic bifurcation, right renal artery, and conus medullaris when locating lumbar vertebral segments. AJR Am J Roentgenol 182(5):1295–1300CrossRefPubMed Lee CH et al (2004) Using MRI to evaluate anatomic significance of aortic bifurcation, right renal artery, and conus medullaris when locating lumbar vertebral segments. AJR Am J Roentgenol 182(5):1295–1300CrossRefPubMed
41.
go back to reference Kershenovich A et al (2016) Conus medullaris level in vertebral columns with lumbosacral transitional vertebra. Neurosurgery 78(1):62–70CrossRefPubMed Kershenovich A et al (2016) Conus medullaris level in vertebral columns with lumbosacral transitional vertebra. Neurosurgery 78(1):62–70CrossRefPubMed
42.
go back to reference Kornreich L et al (1998) Effect of normal ageing on the sites of aortic bifurcation and inferior vena cava confluence: a CT study. Surg Radiol Anat 20(1):63–68CrossRefPubMed Kornreich L et al (1998) Effect of normal ageing on the sites of aortic bifurcation and inferior vena cava confluence: a CT study. Surg Radiol Anat 20(1):63–68CrossRefPubMed
43.
go back to reference Bailey W, Carter RA (1938) Anomalies of the spine: a correlation of anatomical, roentgenological, and clinical findings. Calif West Med 49(1):46–52 Bailey W, Carter RA (1938) Anomalies of the spine: a correlation of anatomical, roentgenological, and clinical findings. Calif West Med 49(1):46–52
44.
go back to reference Hanson EH et al (2010) Sagittal whole-spine magnetic resonance imaging in 750 consecutive outpatients: accurate determination of the number of lumbar vertebral bodies. J Neurosurg Spine 12(1):47–55CrossRefPubMed Hanson EH et al (2010) Sagittal whole-spine magnetic resonance imaging in 750 consecutive outpatients: accurate determination of the number of lumbar vertebral bodies. J Neurosurg Spine 12(1):47–55CrossRefPubMed
45.
go back to reference Akbar JJ et al (2010) Rapid MRI detection of vertebral numeric variation. AJR Am J Roentgenol 195(2):465–466CrossRefPubMed Akbar JJ et al (2010) Rapid MRI detection of vertebral numeric variation. AJR Am J Roentgenol 195(2):465–466CrossRefPubMed
46.
go back to reference Moustafa AHMN, Gawad EAMA, El-Khadrawi TAA (2011) Multidetector CT of the vertebral column: count with confidence & get trusted level for surgery. El-Minia Med Bull 22(2):11 Moustafa AHMN, Gawad EAMA, El-Khadrawi TAA (2011) Multidetector CT of the vertebral column: count with confidence & get trusted level for surgery. El-Minia Med Bull 22(2):11
47.
48.
go back to reference Farshad-Amacker NA et al (2015) Merits of different anatomical landmarks for correct numbering of the lumbar vertebrae in lumbosacral transitional anomalies. Eur Spine J 24(3):600–608CrossRefPubMed Farshad-Amacker NA et al (2015) Merits of different anatomical landmarks for correct numbering of the lumbar vertebrae in lumbosacral transitional anomalies. Eur Spine J 24(3):600–608CrossRefPubMed
49.
go back to reference Weiss KL, Storrs JM, Banto RB (2006) Automated spine survey iterative scan technique. Radiology 239(1):255–262CrossRefPubMed Weiss KL, Storrs JM, Banto RB (2006) Automated spine survey iterative scan technique. Radiology 239(1):255–262CrossRefPubMed
51.
go back to reference Sarawagi R, Kankanala S, Gupta S (2016) Detection of numeric and morphological variation at lumbosacral junction: role of whole spine magnetic resonance imaging. West Afr J Radiol 23(2):95–100CrossRef Sarawagi R, Kankanala S, Gupta S (2016) Detection of numeric and morphological variation at lumbosacral junction: role of whole spine magnetic resonance imaging. West Afr J Radiol 23(2):95–100CrossRef
Metadata
Title
A review of lumbosacral transitional vertebrae and associated vertebral numeration
Authors
Jayson Lian
Nicole Levine
Woojin Cho
Publication date
01-05-2018
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 5/2018
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-018-5554-8

Other articles of this Issue 5/2018

European Spine Journal 5/2018 Go to the issue