Skip to main content
Top
Published in: International Urogynecology Journal 11/2014

01-11-2014 | Original Article

A retrospective comparison of ring pessary and multicomponent behavioral therapy in managing overactive bladder

Authors: Eddie H. M. Sze, Gerry Hobbs

Published in: International Urogynecology Journal | Issue 11/2014

Login to get access

Abstract

Introduction and hypothesis

Overactive bladder (OAB) is a physically, psychologically, and socially disabling condition that affects millions of women worldwide and is especially prevalent postmenopause. The objective of our study was to compare the cure rates of ring pessary with those of multicomponent behavioral therapy in managing overactive bladder.

Methods

We performed a comparative retrospective parallel cohort study of all women whose overactive bladder was treated with multicomponent behavioral therapy or ring pessary over a 42-month period. At the end of the 6-month treatment period, cure was defined as the subjective (self-reported) absence of urinary urgency, frequency, nocturia, and urge incontinence in the preceding 30 days; the objective absence of these symptoms in a 7-day voiding diary; and a Patient Global Impression of Improvement response of “much better” or “very much better.”

Results

Ring pessary and multicomponent behavioral therapy had similar cure rates (29 out of 150 [19 %] vs 46 out of 231 [20 %] respectively, P = 0.889; OR of 1.04, 95 % confidence interval 0.618–1.742, P = 0.887). They also produced comparable cure rates in premenopausal (4 out of 31 [13 %] vs 14 out of 68 [21 %], P = 0.358) and postmenopausal subjects (25/ out of 19 [21 %] vs 32 out of 163 [20 %], P = 0.776), and in women who had undergone previous treatment (21 out of 108 [19 %] vs 31 out of 176 [18 %], P = 0.699) and those who had not (8 out of 42 [19 %] vs 15 out of 55 [27 %], P = 0.345). Logistic regression showed that neither treatment outcome is significantly associated with demographic characteristics; Pelvic Organ Prolapse Quantification at the anterior and posterior vaginal walls and at the vaginal cuff; previous treatment; overactive bladder symptoms; pad usage; or any combination thereof.

Conclusions

Ring pessary has a cure rate similar to that of multicomponent behavioral therapy in managing overactive bladder.
Literature
1.
go back to reference Clemons JL, Aguilar VC, Tillinghast TA, Jackson ND, Myers D (2004) Patient satisfaction and changes in prolapse and urinary symptoms in women who were fitted successfully with a pessary for pelvic organ prolapse. Am J Obstet Gynecol 190:1025–1029PubMedCrossRef Clemons JL, Aguilar VC, Tillinghast TA, Jackson ND, Myers D (2004) Patient satisfaction and changes in prolapse and urinary symptoms in women who were fitted successfully with a pessary for pelvic organ prolapse. Am J Obstet Gynecol 190:1025–1029PubMedCrossRef
2.
go back to reference Fernando RJ, Thakar R, Sultan AH, Shah SM, Jones PW (2006) Effect of vaginal pessaries on symptoms associated with pelvic organ prolapse. Obstet Gynecol 108:93–99PubMedCrossRef Fernando RJ, Thakar R, Sultan AH, Shah SM, Jones PW (2006) Effect of vaginal pessaries on symptoms associated with pelvic organ prolapse. Obstet Gynecol 108:93–99PubMedCrossRef
3.
go back to reference Hanson LAM, Schulz JA, Flood CG, Cooley B, Tam F (2006) Vaginal pessaries in managing women with pelvic organ prolapse and urinary incontinence: patient characteristics and factors contributing to success. Int Urogynecol J 17:155–159CrossRef Hanson LAM, Schulz JA, Flood CG, Cooley B, Tam F (2006) Vaginal pessaries in managing women with pelvic organ prolapse and urinary incontinence: patient characteristics and factors contributing to success. Int Urogynecol J 17:155–159CrossRef
4.
go back to reference Gormley EA, Lightner DJ, Burgio KL, Chai TC, Clemens Q, Culkin DJ et al (2012) Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline. J Urol 188:2455–2463PubMedCrossRef Gormley EA, Lightner DJ, Burgio KL, Chai TC, Clemens Q, Culkin DJ et al (2012) Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline. J Urol 188:2455–2463PubMedCrossRef
5.
go back to reference Sze EHM, Hobbs G (2009) Efficacy of methylcellulose and loperamide in managing fecal incontinence. Acta Obstet Gynecol 88(7):766–771CrossRef Sze EHM, Hobbs G (2009) Efficacy of methylcellulose and loperamide in managing fecal incontinence. Acta Obstet Gynecol 88(7):766–771CrossRef
6.
go back to reference Yalcin I, Bump RC (2003) Validation of two global impression questionnaires for incontinence. Am J Obstet Gynecol 189:98–101PubMedCrossRef Yalcin I, Bump RC (2003) Validation of two global impression questionnaires for incontinence. Am J Obstet Gynecol 189:98–101PubMedCrossRef
7.
go back to reference Brubaker L, Richter HE, Visco A, Mahajan S, Nygaard I, Braun TM et al (2008) Refractory idiopathic urge urinary incontinence and botulinum A injection. J Urol 180:217–222PubMedCrossRefPubMedCentral Brubaker L, Richter HE, Visco A, Mahajan S, Nygaard I, Braun TM et al (2008) Refractory idiopathic urge urinary incontinence and botulinum A injection. J Urol 180:217–222PubMedCrossRefPubMedCentral
8.
go back to reference Swithinbank L, Hashim H, Abrams P (2005) The effect of fluid intake on urinary symptoms in women. J Urol 174:187–189PubMedCrossRef Swithinbank L, Hashim H, Abrams P (2005) The effect of fluid intake on urinary symptoms in women. J Urol 174:187–189PubMedCrossRef
9.
go back to reference Bryant CM, Dowell CJ, Fairbrother G (2002) Caffeine reduction education to improve urinary symptoms. Br J Nurs 11:560–565PubMedCrossRef Bryant CM, Dowell CJ, Fairbrother G (2002) Caffeine reduction education to improve urinary symptoms. Br J Nurs 11:560–565PubMedCrossRef
10.
go back to reference Arya LA, Myers DL, Jackson ND (2000) Dietary caffeine intake and the risk for detrusor instability: a case-control study. Obstet Gynecol 96:85–89PubMedCrossRef Arya LA, Myers DL, Jackson ND (2000) Dietary caffeine intake and the risk for detrusor instability: a case-control study. Obstet Gynecol 96:85–89PubMedCrossRef
12.
go back to reference Basu M, Duckett J (2009) Effect of prolapse repair on voiding and the relationship to overactive bladder and detrusor overactivity. Int Urogynecol J Pelvic Floor Dysfunct 20:499–504PubMedCrossRef Basu M, Duckett J (2009) Effect of prolapse repair on voiding and the relationship to overactive bladder and detrusor overactivity. Int Urogynecol J Pelvic Floor Dysfunct 20:499–504PubMedCrossRef
13.
go back to reference Abrams P (1985) Detrusor instability and bladder outlet obstruction. Neurourol Urodyn 4:317–319CrossRef Abrams P (1985) Detrusor instability and bladder outlet obstruction. Neurourol Urodyn 4:317–319CrossRef
14.
go back to reference Ditz HP, Clarke B (2001) Is the irritable bladder associated with anterior compartment relaxation? A critical look at the integral theory of pelvic floor dysfunction. Aust N Z J Obstet Gynaecol 41:317–319CrossRef Ditz HP, Clarke B (2001) Is the irritable bladder associated with anterior compartment relaxation? A critical look at the integral theory of pelvic floor dysfunction. Aust N Z J Obstet Gynaecol 41:317–319CrossRef
15.
go back to reference Rosenzweig BA, Soffici AR, Thomas S, Bhatia NN (1992) Urodynamic evaluation of voiding in women with cystocele. J Reprod Med 37:162–166PubMed Rosenzweig BA, Soffici AR, Thomas S, Bhatia NN (1992) Urodynamic evaluation of voiding in women with cystocele. J Reprod Med 37:162–166PubMed
16.
go back to reference Burgio KL, Locher JL, Goode PS, Hardin JM, McDowell BJ, Dombrowski M et al (1998) Behavorial vs. drug treatment for urge urinary incontinence in older women. A randomized controlled trial. JAMA 280:1995–2000PubMedCrossRef Burgio KL, Locher JL, Goode PS, Hardin JM, McDowell BJ, Dombrowski M et al (1998) Behavorial vs. drug treatment for urge urinary incontinence in older women. A randomized controlled trial. JAMA 280:1995–2000PubMedCrossRef
17.
go back to reference Huang AJ, Hess R, Arya LA, Richter HE, Subal LL, Bradley CS et al (2012) Pharmacologic treatment for urge-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial. Am J Obstet Gynecol 206:444.e1–444.e11 Huang AJ, Hess R, Arya LA, Richter HE, Subal LL, Bradley CS et al (2012) Pharmacologic treatment for urge-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial. Am J Obstet Gynecol 206:444.e1–444.e11
18.
go back to reference Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Neurourol Urodyn 21:167–178PubMedCrossRef Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Neurourol Urodyn 21:167–178PubMedCrossRef
19.
go back to reference Visco AG, Weidner AC, Cundiff GW, Bump RC (1999) Observed patient compliance with a structured outpatient bladder retraining program. Am J Obstet Gynecol 181:1392–1394PubMedCrossRef Visco AG, Weidner AC, Cundiff GW, Bump RC (1999) Observed patient compliance with a structured outpatient bladder retraining program. Am J Obstet Gynecol 181:1392–1394PubMedCrossRef
20.
go back to reference Diokno AC, Appell RA, Sand PK, Dmochowski RR, Gburek BM, Klimberg IW et al (2003) Prospective, randomized, double-blind study of the efficacy and tolerability of the extended-release formulations of oxybutynin and tolterodine for overactive bladder: results of OPERA trial. Mayo Clin Proc 78:687–695PubMedCrossRef Diokno AC, Appell RA, Sand PK, Dmochowski RR, Gburek BM, Klimberg IW et al (2003) Prospective, randomized, double-blind study of the efficacy and tolerability of the extended-release formulations of oxybutynin and tolterodine for overactive bladder: results of OPERA trial. Mayo Clin Proc 78:687–695PubMedCrossRef
21.
go back to reference Drutz HP, Appell RA, Gleason D, Klimbrg I, Radomski S (1999) Clinical efficacy and safety of tolterodine compared to oxybutynin and placebo in patients with overactive bladder. Int Urogynecol J 10:283–289CrossRef Drutz HP, Appell RA, Gleason D, Klimbrg I, Radomski S (1999) Clinical efficacy and safety of tolterodine compared to oxybutynin and placebo in patients with overactive bladder. Int Urogynecol J 10:283–289CrossRef
Metadata
Title
A retrospective comparison of ring pessary and multicomponent behavioral therapy in managing overactive bladder
Authors
Eddie H. M. Sze
Gerry Hobbs
Publication date
01-11-2014
Publisher
Springer London
Published in
International Urogynecology Journal / Issue 11/2014
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-014-2397-7

Other articles of this Issue 11/2014

International Urogynecology Journal 11/2014 Go to the issue