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Published in: Nuclear Medicine and Molecular Imaging 2/2013

01-06-2013 | Interesting Image

A Rare Case of Malignant Granular Cell Tumor of the Colon Incidentally Detected by 18 F-FDG Positron Emission Tomography/Computed Tomography

Authors: Giorgio Treglia, Marilda Mormando, Donato Iacovazzo, Carmelo Caldarella, Barbara Muoio, Antonio Bianchi, Riccardo Ricci

Published in: Nuclear Medicine and Molecular Imaging | Issue 2/2013

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Excerpt

We report an unusual case of malignant granular cell tumor (GCT) of the colon incidentally detected by Fluorine-18-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in a 54-year-old female patient with history of pulmonary adenocarcinoma. 18F-FDG-PET/CT showed an area of increased radiopharmaceutical uptake, corresponding to a 3 cm nodule in the caecum. Based on PET/CT findings, the patient underwent endoscopic resection of the colonic lesion. Histology demonstrated the presence of a malignant GCT of the colon (Figs. 1 and 2). …
Literature
1.
go back to reference Rekhi B, Jambhekar NA. Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center. Ann Diagn Pathol. 2010;14:162–7.PubMedCrossRef Rekhi B, Jambhekar NA. Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center. Ann Diagn Pathol. 2010;14:162–7.PubMedCrossRef
2.
go back to reference Saleh H, El-Fakharany M, Frankle M. Multiple synchronous granular cell tumors involving the colon, appendix and mesentery: a case report and review of the literature. J Gastrointest Liver Dis. 2009;18:475–8. Saleh H, El-Fakharany M, Frankle M. Multiple synchronous granular cell tumors involving the colon, appendix and mesentery: a case report and review of the literature. J Gastrointest Liver Dis. 2009;18:475–8.
3.
go back to reference Thacker MM, Humble SD, Mounasamy V, et al. Granular cell tumors of extremities: comparison of benign and malignant variants. Clin Orthop Relat Res. 2007;455:267–73.PubMedCrossRef Thacker MM, Humble SD, Mounasamy V, et al. Granular cell tumors of extremities: comparison of benign and malignant variants. Clin Orthop Relat Res. 2007;455:267–73.PubMedCrossRef
4.
go back to reference Hamada K, Fujimoto T, Omori S, et al. FDG PET-CT evaluation of granular cell tumor of the soft tissue. Clin Nucl Med. 2010;35:192–3.PubMedCrossRef Hamada K, Fujimoto T, Omori S, et al. FDG PET-CT evaluation of granular cell tumor of the soft tissue. Clin Nucl Med. 2010;35:192–3.PubMedCrossRef
5.
6.
go back to reference Di Cicilia R, Castellucci P, Nannini M, et al. Unusual finding of benign abrikossoff tumor by F-18 FDG-PET mimicking melanoma recurrence. Clin Nucl Med. 2009;34:696–7.PubMedCrossRef Di Cicilia R, Castellucci P, Nannini M, et al. Unusual finding of benign abrikossoff tumor by F-18 FDG-PET mimicking melanoma recurrence. Clin Nucl Med. 2009;34:696–7.PubMedCrossRef
7.
go back to reference Hoess C, Freitag K, Kolben M, et al. FDG PET evaluation of granular cell tumor of the breast. J Nucl Med. 1998;39:1398–401.PubMed Hoess C, Freitag K, Kolben M, et al. FDG PET evaluation of granular cell tumor of the breast. J Nucl Med. 1998;39:1398–401.PubMed
8.
go back to reference Oh JR, Min JJ, Song HC, et al. A stepwise approach using metabolic volume and SUVmax to differentiate malignancy and dysplasia from benign colonic uptakes on 18 F-FDG PET/CT. Clin Nucl Med. 2012;37:e134–40.PubMedCrossRef Oh JR, Min JJ, Song HC, et al. A stepwise approach using metabolic volume and SUVmax to differentiate malignancy and dysplasia from benign colonic uptakes on 18 F-FDG PET/CT. Clin Nucl Med. 2012;37:e134–40.PubMedCrossRef
9.
go back to reference Treglia G, Calcagni ML, Rufini V, et al. Clinical significance of incidental focal colorectal (18)F-fluorodeoxyglucose uptake: our experience and a review of the literature. Colorectal Dis. 2012;14:174–80.PubMedCrossRef Treglia G, Calcagni ML, Rufini V, et al. Clinical significance of incidental focal colorectal (18)F-fluorodeoxyglucose uptake: our experience and a review of the literature. Colorectal Dis. 2012;14:174–80.PubMedCrossRef
Metadata
Title
A Rare Case of Malignant Granular Cell Tumor of the Colon Incidentally Detected by 18 F-FDG Positron Emission Tomography/Computed Tomography
Authors
Giorgio Treglia
Marilda Mormando
Donato Iacovazzo
Carmelo Caldarella
Barbara Muoio
Antonio Bianchi
Riccardo Ricci
Publication date
01-06-2013
Publisher
Springer-Verlag
Published in
Nuclear Medicine and Molecular Imaging / Issue 2/2013
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-013-0192-x

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