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Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 7/2014

01-08-2014 | Original Article

A randomized study of the effect of carbonated water prior to myocardial SPECT

Authors: Ilse A. C. Vermeltfoort, Arjan B. van Dijk, Jeroen A. F. de Jong, Gerrit J. J. Teule, Marjon Gevers, Bas Verhoeven, Esther Raaijmakers, Paul Knaapen, Pieter G. H. M. Raijmakers

Published in: Annals of Nuclear Medicine | Issue 7/2014

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Abstract

Objective

In myocardial perfusion single-photon emission computed tomography (SPECT), abdominal activity often interferes with the evaluation of perfusion in the inferior wall, especially after pharmacological stress. In this randomized study, we examined the effect of carbonated water intake versus still water intake on the quality of images obtained during myocardial perfusion images (MPI) studies.

Methods

A total of 467 MIBI studies were randomized into a carbonated water group and a water group. The presence of intestinal activity adjacent to the inferior wall was evaluated by two observers. Furthermore, a semi-quantitative analysis was performed in the adenosine subgroup, using a count ratio of the inferior myocardial wall and adjacent abdominal activity.

Results

The need for repeated SPECT in the adenosine studies was 5.3 % in the carbonated water group versus 19.4 % in the still water group (p = 0.019). The inferior wall-to-abdomen count ratio was significantly higher in the carbonated water group compared to the still water group (2.11 ± 1.00 vs. 1.72 ± 0.73, p < 0.001). The effect of carbonated water during rest and after exercise was not significant.

Conclusions

This randomized study showed that carbonated water significantly reduced the interference of extra-cardiac activity in adenosine SPECT MPI.
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Metadata
Title
A randomized study of the effect of carbonated water prior to myocardial SPECT
Authors
Ilse A. C. Vermeltfoort
Arjan B. van Dijk
Jeroen A. F. de Jong
Gerrit J. J. Teule
Marjon Gevers
Bas Verhoeven
Esther Raaijmakers
Paul Knaapen
Pieter G. H. M. Raijmakers
Publication date
01-08-2014
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 7/2014
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-014-0863-4

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