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international journal of stomatology & occlusion medicine

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01-03-2012 | original article

A prospective randomized double-blind study to assess the latency and efficacy of articaine and lignocaine in surgical removal of impacted mandibular third molars in Indian patients

Authors: Sreekumar K., MDS, MFDSRCPS, Darpan Bhargava, MDS, MOMSRCPS(Glasg), PDCR, PGDHM

Published in: international journal of stomatology & occlusion medicine | Issue 1/2012

Abstract

Aim

The aim of this study was to compare anesthetic latency and efficacy of articaine and lignocaine in surgical extraction of impacted mandibular third molars.

Methods

A prospective randomized double-blind clinical trial was conducted on 20 subjects planned for elective surgical removal of bilateral impacted mandibular third molars with similar difficulty indices. A single operator performed surgery on an extemporaneous basis using 4% articaine or 2% lignocaine as the anesthetic agent and with the same concentration of vasoconstrictor (epinephrine 1:100,000). The parameters considered were latency, duration of anesthetic effect and the need for re-anesthesia for the surgical procedure. A visual analog scale was used to score pain during procedure.

Results

The differences in latency with 4% articaine (66.65 ± 12.3 s) and 2% lignocaine (72.95 ± 9.4 s) and mean duration of anesthetic effect (240.3 ± 29.6 min for 4% articaine and 173.4 ± 18.6 min for 2% lignocaine) were found to be statistically significant and the pain scores obtained were on the higher end for lignocaine but were not statistically significant (2.15 for 4% articaine and 3.75 for 2% lignocaine).

Conclusions

The results suggest that 4% articaine is superior to 2% lignocaine in terms of latency, duration of the anesthesia and pain control in surgical removal of impacted mandibular third molars, although a multicentric study with a larger sample size is essential to validate the findings with statistical correlation.

Huang YD, Xia H, Li XD, Yang XZ, Pei ZQ, Xia X. A comparison of the clinical anesthetic efficacy of articaine infiltration and lidocaine blocking for microport extraction of impacted mandibular molar. Hua Xi Kou Qiang Yi Xue Za Zhi. 2011;29(3):268–71.PubMed

Abdulwahab M, Boynes S, Moore P, Seifikar S, Al-Jazzaf A, Alshuraidah A, et al. The efficacy of six local anesthetic formulations used for posterior mandibular buccal infiltration anesthesia. J Am Dent Assoc. 2009;140(8):1018–24.PubMed

Malamed SF, Gagnon S, Leblanc D. Efficacy of articaine: a new amide local anesthetic. J Am Dent Assoc. 2000;131:635–42.PubMed

Sierra Rebolledo A, Delgado Molina E, Berini Aytís L, Gay Escoda C. Comparative study of the anesthetic efficacy of 4% articaine versus 2% lidocaine in inferior alveolar nerve block during surgical extraction of impacted lower third molars. Med Oral Patol Oral Cir Bucal. 2007;12(2):E139–44.PubMed

Sreekumar K, Bhargava D. Comparison of onset and duration of action of soft tissue and pulpal anesthesia with three volumes of 4% articaine with 1:100,000 epinephrine in maxillary infiltration anesthesia. Oral Maxillofac Surg. 2011 Dec;15(4):195–9.

Katyal V. The efficacy and safety of articaine versus lignocaine in dental treatments: a meta-analysis. J Dent. 2010;38(4):307–17.PubMedCrossRef

Yuasa H, Kawai T, Suguira M. Classification of surgical difficulty in extracting impacted third molars. Br J Oral Maxillofac Surg. 2002;40:26–31.PubMedCrossRef

Costa CG, Tortamano IP, Rocha RG, Francischone CE, Tortamano N. Onset and duration periods of articaine and lidocaine on maxillary infiltration. Quintessence Int. 2005;36(3):197–201.PubMed

Kanaa MD, Whitworth JM, Corbett IP, Meechan JG. Articaine and lidocaine mandibular buccal infiltration anesthesia: a prospective randomized double-blind cross-over study. J Endod. 2000;32(4):296–8.CrossRef

10.

Vahatalo K, Antila H, Lehtinen R. Articaine and lidocaine for maxillary infiltration anesthesia. Anesth Prog. 1993;40:114–6.PubMed

11.

Claffey E, Reader A, Nusstein J, Beck M, Weaver J. Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis. J Endod. 2004;30(8):568–71.PubMedCrossRef

12.

Mikesell P, Nusstein J, Reader A, Beck M, Weaver J. A comparison of articaine and lidocaine for inferior alveolar nerve blocks. J Endod. 2005;31:265–70.PubMedCrossRef

13.

Haas DA, Lennon D. A 21-year retrospective study of reports of paresthesia following local anesthetic administration. J Can Dent Assoc. 1995;61:319–20.PubMed

14.

Penarrocha-Diago M, Sanchis-Bielsa JM. Ophthalmologic complications after intraoral local anesthesia with articaine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:21–4.PubMedCrossRef

15.

Cowan A. Clinical assessment of a new local anesthetic agent: carticaine. Oral Surg Oral Med Oral Pathol. 1977;43:174–80.PubMedCrossRef

16.

Malamed SF. Hand book of local anesthesia. 5th ed. St Louis: Mosby; 2004.

17.

Berini-Aytés L, Gay-Escoda C. Anestesia Odontológica. 2nd ed. Madrid: Ediciones Avances Medico-Dentales; 2000.

18.

Lemay H, Albert G, Helie P, Dufour L, Gagnon P, Payant L, et al. Ultracaine in conventional operative dentistry. J Can Dent Assoc. 1984;50:703–708.PubMed

19.

Martínez-González JM, Benito Peña B, Fernández Cáliz F, San Hipólito Marín L, Peñarrocha Diago M. Estudio comparativo entre el bloqueo mandibular directo y la técnica de Akinosi. Med Oral. 2003;8:143–149.PubMed

20.

Daublander M, Muller R, Lipp MD. The incidence of complications associated with local anesthesia in dentistry. Anesth Prog. 1997;44:132–41.PubMed

21.

Lipp M, Daublander M. Aspekte hiesiger Anästhesie in Patienten bei koronarer Herzkrankheit. Quintessenz. 1991;42:983–90.PubMed

Title: A prospective randomized double-blind study to assess the latency and efficacy of articaine and lignocaine in surgical removal of impacted mandibular third molars in Indian patients
Authors: Sreekumar K., MDS, MFDSRCPS
Darpan Bhargava, MDS, MOMSRCPS(Glasg), PDCR, PGDHM
Publication date: 01-03-2012
Publisher: Springer Vienna
Published in: international journal of stomatology & occlusion medicine / Issue 1/2012
Print ISSN: 1867-2221
Electronic ISSN: 1867-223X
DOI: https://doi.org/10.1007/s12548-011-0031-6

At a glance: The STEP trials

Springer Medicine

A prospective randomized double-blind study to assess the latency and efficacy of articaine and lignocaine in surgical removal of impacted mandibular third molars in Indian patients

Abstract

Aim

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Aim

Methods

Results

Conclusions

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