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Child's Nervous System
Published in: Child's Nervous System 7/2011

01-07-2011 | Case Report

A primary intrasellar mixed germ cell tumor with suprasellar extension

Authors: Joo Pyung Kim, Bong Jin Park, Young Jin Lim

Published in: Child's Nervous System | Issue 7/2011

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Excerpt

Primary intracranial germ cell tumors (GCT) account for 0.4–3.4% [7] of all pediatric central nervous system tumors in Caucasians and 2.1–9.4% [4, 6, 13] of all pediatric central nervous system tumors in Asians. Mixed GCTs make up approximately 25% of all intracranial GCTs, and mixed germinomas with matured teratomas make up approximately 4% of all the mixed germ cell tumors [3]. It has been shown that 76–90% of GCTs are located in the pineal and suprasellar regions [9]. In addition, this tumor may occur in the basal ganglia, cerebellar vermis, pituitary fossa, ventricular system, optic chiasm, cerebral hemispheres, or in the medulla oblongata [9]. GCT is known to preferentially occur in the pineal region in males and in the suprasellar region in females [7]. GCT is usually classified into two types, germinomatous and nongerminomatous germ cell tumors (NGGCT), with the germinomatous type accounting for 50–70% of the GCTs [7]. …
Literature
1.
Andre F, Fizazi K, Culine S, Droz J, Taupin P, Lhomme C, Terrier-Lacombe M, Theodore C (2000) The growing teratoma syndrome: results of therapy and long-term follow-up of 33 patients. Eur J Cancer 36:1389–1394PubMedCrossRef
2.
Haas-Kogan DA, Missett BT, Wara WM, Donaldson SS, Lamborn KR, Prados MD, Fisher PG, Huhn SL, Fisch BM, Berger MS, Le QT (2003) Radiation therapy for intracranial germ cell tumors. Int J Radiat Oncol Biol Phys 56:511–518PubMedCrossRef
3.
Ho DM, Liu HC (1992) Primary intracranial germ cell tumor. Pathologic study of 51 patients. Cancer 70:1577–1584PubMedCrossRef
4.
Hoffman HJ, Otsubo H, Hendrick EB, Humphreys RP, Drake JM, Becker LE, Greenberg M, Jenkin D (1991) Intracranial germ-cell tumors in children. J Neurosurg 74:545–551PubMedCrossRef
5.
Horowitz MB, Hall WA (1991) Central nervous system germinomas. A review. Arch Neurol 48:652–657PubMed
6.
7.
Jennings MT, Gelman R, Hochberg F (1985) Intracranial germ-cell tumors: natural history and pathogenesis. J Neurosurg 63:155–167PubMedCrossRef
8.
Kong DS, Nam DH, Lee JI, Park K, Kim JH, Shin HJ (2009) Intracranial growing teratoma syndrome mimicking tumor relapse: a diagnostic dilemma. J Neurosurg Pediatr 3:392–396PubMedCrossRef
9.
Liang L, Korogi Y, Sugahara T, Ikushima I, Shigematsu Y, Okuda T, Takahashi M, Kochi M, Ushio Y (2002) MRI of intracranial germ-cell tumours. Neuroradiology 44:382–388PubMedCrossRef
10.
Linstadt D, Wara WM, Edwards MS, Hudgins RJ, Sheline GE (1988) Radiotherapy of primary intracranial germinomas: the case against routine craniospinal irradiation. Int J Radiat Oncol Biol Phys 15:291–297PubMedCrossRef
11.
Packer RJ, Cohen BH, Cooney K (2000) Intracranial germ cell tumors. Oncologist 5:312–320PubMed
12.
Sano K, Matsutani M, Seto T (1989) So-called intracranial germ cell tumours: personal experiences and a theory of their pathogenesis. Neurol Res 11:118–126PubMed
13.
Shim KW, Kim TG, Suh CO, Cho JH, Yoo CJ, Choi JU, Kim JH, Kim DS (2007) Treatment failure in intracranial primary germinomas. Childs Nerv Syst 23:1155–1161PubMedCrossRef
14.
Weiner HL, Lichtenbaum RA, Wisoff JH, Snow RB, Souweidane MM, Bruce JN, Finlay JL (2002) Delayed surgical resection of central nervous system germ cell tumors. Neurosurgery 50:727–733, discussion 733–734PubMedCrossRef
15.
Wildemberg LE, Neto LV, Taboada GF, Moraes AB, Marcondes J, Conceicao FL, Chimelli L, Gadelha MR (2011) Sellar and suprasellar mixed germ cell tumor mimicking a pituitary adenoma. Pituitary. doi:10.​1007/​s11102-008-0161-z
Metadata
Title
A primary intrasellar mixed germ cell tumor with suprasellar extension
Authors
Joo Pyung Kim
Bong Jin Park
Young Jin Lim
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 7/2011
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-011-1415-z

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