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Clinical Phytoscience
Published in: Clinical Phytoscience 1/2017

Open Access 01-01-2017 | Short communication

A preliminary evaluation of effects of high doses of Jujube and Saffron on biochemical and hematological parameters in rats

Authors: Banafsheh Safizadeh, Reyhane Hoshyar, Mina Hemmati, Asghar Zarban, Roshanak Ebrahimi

Published in: Clinical Phytoscience | Issue 1/2017

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Abstract

We investigated effects of high doses of Jujube fruits and Saffron petals on biochemical and hematological biomarkers in rats. During 14 days treatment of herbs, mortality was not observed. No difference reported in FBS, lipid profile, total protein, albumin, total bilirubin and hematological parameters of rats after treatments. BUN, cratinine, urate and liver enzymes levels in both extracts increased. These changes were more noticeable in Saffron compared with Jujube. This study can suggest that administration of high doses of Jujube (up 5000 mg/kg) and Saffron (up 2000 mg/kg) are nearly safe, also did not exert hepato and nephrotoxicity in rats.
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Metadata
Title
A preliminary evaluation of effects of high doses of Jujube and Saffron on biochemical and hematological parameters in rats
Authors
Banafsheh Safizadeh
Reyhane Hoshyar
Mina Hemmati
Asghar Zarban
Roshanak Ebrahimi
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
Clinical Phytoscience / Issue 1/2017
Electronic ISSN: 2199-1197
DOI
https://doi.org/10.1186/s40816-016-0029-0

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