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Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 9/2010

01-11-2010 | Original Article

A practical method of determining cross-calibration factors of PET scanners by moving a point-like 22Na radioactive source

Authors: Tomoyuki Hasegawa, Keiichi Oda, Yasuhiro Wada, Yasushi Sato, Takahiro Yamada, Eiji Yoshida, Hideo Murayama, Kyoko Saito, Tohoru Takeda, Kei Kikuchi

Published in: Annals of Nuclear Medicine | Issue 9/2010

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Abstract

Purpose

Thus far, cylindrical phantoms with 18F or 68Ge/68Ga have been used in the standard techniques for determining the cross-calibration factors (CCFs) of PET scanners. This paper describes a new practical method that uses a point-like 22Na radioactive source for determining CCFs.

Methods

A point-like 22Na radioactive source (about 700 kBq) was equipped with a spherical aluminium absorber capsule to ensure the symmetry of the emitted photons. During measurements, the source was moved in the axial direction to cover the whole axial field of view (FOV) of a clinical PET scanner, SET-2400 W. The region-of-interest (ROI) values obtained in reconstructed images without scatter and attenuation corrections were used to calculate the CCFs of the PET scanner.

Results

The CCFs obtained by the proposed method agreed with those obtained by the standard cross-calibration (CC) method within a precision of 1.5% (σ). The temporal variations in the CCFs by the standard CC method were reproduced by the proposed method with a precision better than 1%.

Conclusion

The CC method with a moving 22Na point-like radioactive source is practically useful for determining the CCFs of PET scanners and monitoring their variations.
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Metadata
Title
A practical method of determining cross-calibration factors of PET scanners by moving a point-like 22Na radioactive source
Authors
Tomoyuki Hasegawa
Keiichi Oda
Yasuhiro Wada
Yasushi Sato
Takahiro Yamada
Eiji Yoshida
Hideo Murayama
Kyoko Saito
Tohoru Takeda
Kei Kikuchi
Publication date
01-11-2010
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 9/2010
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-010-0403-9

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