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Critical Care
Published in: Critical Care 1/2006

01-02-2006 | Poster presentation

A novel therapeutic concept for the treatment of acute angioedema attacks in hereditary angioedema patients: multiple successful treatments even in severe swelling attacks with the bradykinin-B2 receptor antagonist Icatibant

Authors: M Bas, J Greve, G Kojda, H Bier, T Hoffmann

Published in: Critical Care | Special Issue 1/2006

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Excerpt

Several forms of angioedema seem to be induced by elevated bradykinin (BK) concentrations. They are either caused by increased BK production, as is the case in hereditary angioedema (HAE) involving the lack of a functional C1-esterase inhibitor, or by reduced BK inactivation (e.g. during ACE-inhibitor treatment). BK-induced angioedema does not respond to the current standard treatment for angioedema caused by increased histamine levels, corticosteroids and antihistamines. …
Metadata
Title
A novel therapeutic concept for the treatment of acute angioedema attacks in hereditary angioedema patients: multiple successful treatments even in severe swelling attacks with the bradykinin-B2 receptor antagonist Icatibant
Authors
M Bas
J Greve
G Kojda
H Bier
T Hoffmann
Publication date
01-02-2006
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2006
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc4662

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