Skip to main content
Top
Published in: Hernia 4/2016

01-08-2016 | Original Article

A multi-institutional, propensity-score-matched comparison of post-operative outcomes between general anesthesia and monitored anesthesia care with intravenous sedation in umbilical hernia repair

Authors: M. M. Vu, R. D. Galiano, J. M. Souza, C. Du Qin, J. Y. S. Kim

Published in: Hernia | Issue 4/2016

Login to get access

Abstract

Purpose

Monitored anesthesia care with intravenous sedation (MAC/IV), recently proposed as a good choice for hernia repair, has faster recovery and better patient satisfaction than general anesthesia; however the possibility of oversedation and respiratory distress is a widespread concern. There is a paucity of the literature examining umbilical hernia repairs (UHR) and optimal anesthesia choice, despite its importance in determining clinical outcomes.

Methods

A retrospective analysis of anesthesia type in UHR was performed in the National Surgical Quality Improvement Program 2005–2013 database. General anesthesia and MAC/IV groups were propensity-score-matched (PSM) to reduce treatment selection bias. Surgical complications, medical complications, and post-operative hospital stays exceeding 1 day were the primary outcomes of interest. Pre-operative characteristics and post-operative outcomes were compared between the two anesthesia groups using univariate and multivariate statistics.

Results

PSM removed all observed differences between the two groups (p > 0.05 for all tracked pre-operative characteristics). MAC/IV cases required fewer post-operative hospital stays exceeding 1 day (3.5 vs 6.3 %, p < 0.001). Univariate analysis showed that overall complication rate did not differ (1.7 vs 1.8 %, p = 0.569), however MAC/IV cases resulted in fewer incidences of septic shock (<0.1 vs 0.1 %, p = 0.016). After multivariate logistic regression, MAC/IV was revealed to yield significantly lower chances of overall medical complications (OR = 0.654, p = 0.046).

Conclusion and relevance

UHR under MAC/IV causes fewer medical complications and reduces post-operative hospital stays compared to general anesthesia. The implications for surgeons and patients are broad, including improved surgical safety, cost-effective care, and patient satisfaction.
Literature
1.
go back to reference Tang J, Chen L, White PF, Watcha MF, Wender RH, Naruse R, Kariger R, Sloninsky A (1999) Recovery profile, costs, and patient satisfaction with propofol and sevoflurane for fast-track office-based anesthesia. Anesthesiology 91(1):253–261CrossRefPubMed Tang J, Chen L, White PF, Watcha MF, Wender RH, Naruse R, Kariger R, Sloninsky A (1999) Recovery profile, costs, and patient satisfaction with propofol and sevoflurane for fast-track office-based anesthesia. Anesthesiology 91(1):253–261CrossRefPubMed
2.
go back to reference Song D, Greilich NB, White PF, Watcha MF, Tongier WK (2000) Recovery profiles and costs of anesthesia for outpatient unilateral inguinal herniorrhaphy. Anesth Analg 91(4):876–881CrossRefPubMed Song D, Greilich NB, White PF, Watcha MF, Tongier WK (2000) Recovery profiles and costs of anesthesia for outpatient unilateral inguinal herniorrhaphy. Anesth Analg 91(4):876–881CrossRefPubMed
3.
go back to reference Bitar G, Mullis W, Jacobs W, Matthews D, Beasley M, Smith K, Watterson P, Getz S, Capizzi P, Eaves F 3rd (2003) Safety and efficacy of office-based surgery with monitored anesthesia care/sedation in 4778 consecutive plastic surgery procedures. Plast Reconstr Surg 111(1):150–156. doi:10.1097/01.prs.0000037756.88297.bc discussion 157–158 CrossRefPubMed Bitar G, Mullis W, Jacobs W, Matthews D, Beasley M, Smith K, Watterson P, Getz S, Capizzi P, Eaves F 3rd (2003) Safety and efficacy of office-based surgery with monitored anesthesia care/sedation in 4778 consecutive plastic surgery procedures. Plast Reconstr Surg 111(1):150–156. doi:10.​1097/​01.​prs.​0000037756.​88297.​bc discussion 157–158 CrossRefPubMed
4.
go back to reference De Virgilio C, Romero L, Donayre C, Meek K, Lewis RJ, Lippmann M, Rodriguez C, White R (2002) Endovascular abdominal aortic aneurysm repair with general versus local anesthesia: a comparison of cardiopulmonary morbidity and mortality rates. J Vasc Surg 36(5):988–991CrossRefPubMed De Virgilio C, Romero L, Donayre C, Meek K, Lewis RJ, Lippmann M, Rodriguez C, White R (2002) Endovascular abdominal aortic aneurysm repair with general versus local anesthesia: a comparison of cardiopulmonary morbidity and mortality rates. J Vasc Surg 36(5):988–991CrossRefPubMed
5.
go back to reference Okhunov Z, Juncal S, Ordon M, George AK, Lusch A, del Junco M, Nguyentat M, Lobko II, Kavoussi L, Landman J (2015) Comparison of outcomes in patients undergoing percutaneous renal cryoablation with sedation vs general anesthesia. Urology 85(1):130–134. doi:10.1016/j.urology.2014.09.013 CrossRefPubMed Okhunov Z, Juncal S, Ordon M, George AK, Lusch A, del Junco M, Nguyentat M, Lobko II, Kavoussi L, Landman J (2015) Comparison of outcomes in patients undergoing percutaneous renal cryoablation with sedation vs general anesthesia. Urology 85(1):130–134. doi:10.​1016/​j.​urology.​2014.​09.​013 CrossRefPubMed
6.
go back to reference Segal JL, Owens G, Silva WA, Kleeman SD, Pauls R, Karram MM (2007) A randomized trial of local anesthesia with intravenous sedation vs general anesthesia for the vaginal correction of pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct 18(7):807–812. doi:10.1007/s00192-006-0242-3 CrossRefPubMed Segal JL, Owens G, Silva WA, Kleeman SD, Pauls R, Karram MM (2007) A randomized trial of local anesthesia with intravenous sedation vs general anesthesia for the vaginal correction of pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct 18(7):807–812. doi:10.​1007/​s00192-006-0242-3 CrossRefPubMed
7.
go back to reference Franz R, Hartman J, Wright M (2011) Comparison of anesthesia technique on outcomes of endovascular repair of abdominal aortic aneurysms: a five-year review of monitored anesthesia care with local anesthesia vs. general or regional anesthesia. J Cardiovasc Surg (Torino) 52(4):567–577 Franz R, Hartman J, Wright M (2011) Comparison of anesthesia technique on outcomes of endovascular repair of abdominal aortic aneurysms: a five-year review of monitored anesthesia care with local anesthesia vs. general or regional anesthesia. J Cardiovasc Surg (Torino) 52(4):567–577
8.
go back to reference Bhattacharya SD, Vaslef SN, Pappas TN, Scarborough JE (2012) Locoregional versus general anesthesia for open inguinal herniorrhaphy: A National Surgical Quality Improvement Program analysis. Am Surg 78(7):798–802PubMed Bhattacharya SD, Vaslef SN, Pappas TN, Scarborough JE (2012) Locoregional versus general anesthesia for open inguinal herniorrhaphy: A National Surgical Quality Improvement Program analysis. Am Surg 78(7):798–802PubMed
9.
go back to reference Bhananker SM, Posner KL, Cheney FW, Caplan RA, Lee LA, Domino KB (2006) Injury and liability associated with monitored anesthesia care: a closed claims analysis. Anesthesiology 104(2):228–234CrossRefPubMed Bhananker SM, Posner KL, Cheney FW, Caplan RA, Lee LA, Domino KB (2006) Injury and liability associated with monitored anesthesia care: a closed claims analysis. Anesthesiology 104(2):228–234CrossRefPubMed
10.
go back to reference Tesniere A, Servin F (2003) Intravenous techniques in ambulatory anesthesia. Anesthesiol Clin North America 21(2):273–288CrossRefPubMed Tesniere A, Servin F (2003) Intravenous techniques in ambulatory anesthesia. Anesthesiol Clin North America 21(2):273–288CrossRefPubMed
11.
go back to reference Brahmbhatt R, Carter SA, Hicks SC, Berger DH, Liang MK (2014) Identifying risk factors for surgical site complications after laparoscopic ventral hernia repair: Evaluation of the Ventral Hernia Working Group Grading System. Surg Infect (Larchmt). doi:10.1089/sur.2012.179 Brahmbhatt R, Carter SA, Hicks SC, Berger DH, Liang MK (2014) Identifying risk factors for surgical site complications after laparoscopic ventral hernia repair: Evaluation of the Ventral Hernia Working Group Grading System. Surg Infect (Larchmt). doi:10.​1089/​sur.​2012.​179
12.
go back to reference Fischer JP, Wink JD, Tuggle CT, Nelson JA, Kovach SJ (2015) Wound risk assessment in ventral hernia repair: generation and internal validation of a risk stratification system using the ACS-NSQIP. Hernia 19(1):103–111. doi:10.1007/s10029-014-1318-5 CrossRefPubMed Fischer JP, Wink JD, Tuggle CT, Nelson JA, Kovach SJ (2015) Wound risk assessment in ventral hernia repair: generation and internal validation of a risk stratification system using the ACS-NSQIP. Hernia 19(1):103–111. doi:10.​1007/​s10029-014-1318-5 CrossRefPubMed
13.
go back to reference Kim K, Mella J, Ibrahim AM, Koolen PG, Lin SJ (2014) Analysis of the NSQIP database in 34541 patients undergoing incisonal/ventral hernia repair: the association between the component separation and venous thromboembolism. Plast Reconstr Surg 134(4 Suppl 1):141–142. doi:10.1097/01.prs.0000455516.21635.7d CrossRef Kim K, Mella J, Ibrahim AM, Koolen PG, Lin SJ (2014) Analysis of the NSQIP database in 34541 patients undergoing incisonal/ventral hernia repair: the association between the component separation and venous thromboembolism. Plast Reconstr Surg 134(4 Suppl 1):141–142. doi:10.​1097/​01.​prs.​0000455516.​21635.​7d CrossRef
18.
go back to reference Kulah B, Kulacoglu IH, Oruc MT, Duzgun AP, Moran M, Ozmen MM, Coskun F (2001) Presentation and outcome of incarcerated external hernias in adults. Am J Surg 181(2):101–104CrossRefPubMed Kulah B, Kulacoglu IH, Oruc MT, Duzgun AP, Moran M, Ozmen MM, Coskun F (2001) Presentation and outcome of incarcerated external hernias in adults. Am J Surg 181(2):101–104CrossRefPubMed
20.
go back to reference Kulacoglu H, Yazicioglu D, Ozyaylali I (2012) Prosthetic repair of umbilical hernias in adults with local anesthesia in a day-case setting: a comprehensive report from a specialized hernia center. Hernia 16(2):163–170. doi:10.1007/s10029-011-0888-8 CrossRefPubMed Kulacoglu H, Yazicioglu D, Ozyaylali I (2012) Prosthetic repair of umbilical hernias in adults with local anesthesia in a day-case setting: a comprehensive report from a specialized hernia center. Hernia 16(2):163–170. doi:10.​1007/​s10029-011-0888-8 CrossRefPubMed
22.
go back to reference Ingraham AM, Richards KE, Hall BL, Ko CY (2010) Quality improvement in surgery: the American College of Surgeons National Surgical Quality Improvement Program approach. Adv Surg 44:251–267CrossRefPubMed Ingraham AM, Richards KE, Hall BL, Ko CY (2010) Quality improvement in surgery: the American College of Surgeons National Surgical Quality Improvement Program approach. Adv Surg 44:251–267CrossRefPubMed
25.
go back to reference Austin PC (2011) Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat 10(2):150–161. doi:10.1002/pst.433 CrossRefPubMed Austin PC (2011) Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat 10(2):150–161. doi:10.​1002/​pst.​433 CrossRefPubMed
27.
go back to reference Merkow RP, Bilimoria KY, Hall BL (2011) Interpretation of the C-statistic in the context of ACS-NSQIP models. Ann Surg Oncol 18(Suppl 3):S295 author reply S296 CrossRefPubMed Merkow RP, Bilimoria KY, Hall BL (2011) Interpretation of the C-statistic in the context of ACS-NSQIP models. Ann Surg Oncol 18(Suppl 3):S295 author reply S296 CrossRefPubMed
29.
go back to reference Cho SW, Bhayani N, Newell P, Cassera MA, Hammill CW, Wolf RF, Hansen PD (2012) Umbilical hernia repair in patients with signs of portal hypertension: surgical outcome and predictors of mortality. Arch Surg 147(9):864–869. doi:10.1001/archsurg.2012.1663 CrossRefPubMed Cho SW, Bhayani N, Newell P, Cassera MA, Hammill CW, Wolf RF, Hansen PD (2012) Umbilical hernia repair in patients with signs of portal hypertension: surgical outcome and predictors of mortality. Arch Surg 147(9):864–869. doi:10.​1001/​archsurg.​2012.​1663 CrossRefPubMed
Metadata
Title
A multi-institutional, propensity-score-matched comparison of post-operative outcomes between general anesthesia and monitored anesthesia care with intravenous sedation in umbilical hernia repair
Authors
M. M. Vu
R. D. Galiano
J. M. Souza
C. Du Qin
J. Y. S. Kim
Publication date
01-08-2016
Publisher
Springer Paris
Published in
Hernia / Issue 4/2016
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-015-1455-5

Other articles of this Issue 4/2016

Hernia 4/2016 Go to the issue