Published in:
01-12-2009 | Invited Commentary
A Meta-Analysis of Randomized Controlled Trials Assessing the Prophylactic Use of Ceftriaxone. A Study of Wound, Chest and Urinary Infections
Authors:
Markus Schäfer, Pierre-Alain Clavien
Published in:
World Journal of Surgery
|
Issue 12/2009
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Excerpt
The use of prophylactic antibiotics has been nowadays generally accepted as an important precaution to prevent infectious complications following surgery. Surgeons may sometimes lack the required infectiological knowledge, and to keep an up-dated overview of the extensive literature remains difficult, hence we have to rely on meta-analysis and to benefit from collating information from different meta-analysis [
1]. In this article, Woodfield et al. have shown with their meticulously performed meta-analysis of 90 publications that ceftriaxone is more effective than most other prophylactic antibiotics to reduce surgical site infections, urinary tract infections and postoperative pneumonia in patients at risk [
2]. …