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Journal of Medical Systems
Published in: Journal of Medical Systems 4/2012

01-08-2012 | ORIGINAL PAPER

A Medical Software System for Volumetric Analysis of Cerebral Pathologies in Magnetic Resonance Imaging (MRI) Data

Authors: Jan Egger, Christoph Kappus, Bernd Freisleben, Christopher Nimsky

Published in: Journal of Medical Systems | Issue 4/2012

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Abstract

In this contribution, a medical software system for volumetric analysis of different cerebral pathologies in magnetic resonance imaging (MRI) data is presented. The software system is based on a semi-automatic segmentation algorithm and helps to overcome the time-consuming process of volume determination during monitoring of a patient. After imaging, the parameter settings—including a seed point—are set up in the system and an automatic segmentation is performed by a novel graph-based approach. Manually reviewing the result leads to reseeding, adding seed points or an automatic surface mesh generation. The mesh is saved for monitoring the patient and for comparisons with follow-up scans. Based on the mesh, the system performs a voxelization and volume calculation, which leads to diagnosis and therefore further treatment decisions. The overall system has been tested with different cerebral pathologies—glioblastoma multiforme, pituitary adenomas and cerebral aneurysms– and evaluated against manual expert segmentations using the Dice Similarity Coefficient (DSC). Additionally, intra-physician segmentations have been performed to provide a quality measure for the presented system.
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Metadata
Title
A Medical Software System for Volumetric Analysis of Cerebral Pathologies in Magnetic Resonance Imaging (MRI) Data
Authors
Jan Egger
Christoph Kappus
Bernd Freisleben
Christopher Nimsky
Publication date
01-08-2012
Publisher
Springer US
Published in
Journal of Medical Systems / Issue 4/2012
Print ISSN: 0148-5598
Electronic ISSN: 1573-689X
DOI
https://doi.org/10.1007/s10916-011-9673-6

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