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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 3/2017

01-09-2017 | Maternal-Fetal Medicine

A dose–response relation exists between different classes of pre-gravid obesity and selected perinatal outcomes

Authors: Andreja Trojner Bregar, Nataša Tul, Vesna Fabjan Vodušek, Ivan Verdenik, Miha Lucovnik, Vid Janša, Isaac Blickstein

Published in: Archives of Gynecology and Obstetrics | Issue 3/2017

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Abstract

Objective

To examine if a “dose–response” relation exists between different classes of pre-gravid obesity and selected perinatal outcomes.

Methods

We evaluated 16,566 obese mothers, including 12,064 (72.8%), 3410 (20.6%), and 1092 (6.6%) with obesity class I, II, and III, respectively. We compared maternal age, primiparity, gestational age at birth, birth weight, GDM, hypertensive disorders, and the incidence of cesarean sections.

Results

There was a significantly increased incidence (from class I to class III) for GDM (8.5–14.4%), chronic hypertension (2.8–9.0%), gestational hypertension (6.7–14.2%), and for preeclampsia (5.3–9.3%). No such relationship existed for birth weight and gestational duration.

Conclusion

Classes of obesity during pregnancy exhibit a “dose–response” relationship with maternal morbidity, but no such relationship was found with pregnancy duration and birth weight.
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Metadata
Title
A dose–response relation exists between different classes of pre-gravid obesity and selected perinatal outcomes
Authors
Andreja Trojner Bregar
Nataša Tul
Vesna Fabjan Vodušek
Ivan Verdenik
Miha Lucovnik
Vid Janša
Isaac Blickstein
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
Archives of Gynecology and Obstetrics / Issue 3/2017
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-017-4441-6

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