Published in:
Open Access
01-02-2011 | Poster presentation
A creep in the vancomycin minimum inhibitory concentration for Staphylococcus aureus in a tertiary care hospital in India
Authors:
A Bhakta, M Bhattacharyya, S Todi
Published in:
Critical Care
|
Special Issue 1/2011
Login to get access
Excerpt
Vancomycin minimum inhibitory concentration (MIC) creep has been observed in studies from western countries. Staphylococcus aureus strains with increased MIC to vancomycin are associated with worse outcomes compared with more susceptible strains. Recognition of this phenomenon - the development of reduced susceptibility to vancomycin, and the subsequent glycopeptide MIC creep - is important, since it may be a precursor to heterogeneous vancomycin intermediate S. aureus (hVISA) and VISA. …