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Annals of General Psychiatry
Published in: Annals of General Psychiatry 1/2017

Open Access 01-12-2017 | Case report

A case report of Lhermitte–Duclos disease revealed by psychiatric disturbances

Authors: Yassine Otheman, Rachid Aalouane, Chadia Aarab, Ismail Rammouz

Published in: Annals of General Psychiatry | Issue 1/2017

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Abstract

Background

Lhermitte–Duclos disease (LDD) is a rare cerebellar lesion characterized by a hamartomatous lesion in the posterior fossa. Mainly diagnosed by MRI, the clinical presentation is usually made of neurological symptoms.

Case presentation

We present here a rare case of a woman who developed depressive symptoms that inaugurated the clinical presentation of LDD.

Conclusion

Psychiatric symptoms may occur in all brain lesions, delaying the diagnosis and causing therapeutic escalation. More attention should be given by practitioners to psychiatric aspects of LDD.
Literature
1.
2.
Milbouw G, Born JD, Martin D, et al. Clinical and radiological aspects of dysplastic gangliocytoma (Lhermitte-Duclos disease): a report of two cases with review of the literature. Neurosurgery. 1988;22:124–8.PubMed
3.
Yang MS, Kim CH, Cheong JH, et al. Lhermitte-Duclos disease presenting with hydrocephalus. Acta Neurochir Suppl. 2012;113:161–5.CrossRefPubMed
4.
Huang S, Zhang G, Zhang J. Similar MR imaging characteristics but different pathological changes: a misdiagnosis for Lhermitte-Duclos disease and review of the literature. Int J Clin Exp Pathol. 2015;8(6):7583.PubMedPubMedCentral
5.
Vinchon M, Blond S, Lejeune JP, et al. Association of Lhermitte-Duclos and Cowden disease: report of a new case and review of the literature. J Neurol Neurosurg Psychiatr. 1994;57(6):699–704.CrossRefPubMedPubMedCentral
6.
7.
8.
Wei G, Zhang W, Li Q, et al. Magnetic resonance characteristics of adult-onset Lhermitte-Duclos disease: an indicator for active cancer surveillance? Mol Clin Oncol. 2014;2(3):415–20.PubMedPubMedCentral
9.
Barone F, Noubari BA, Torrisi A, et al. Lhermitte Duclos disease and Cowden disease: clinical, pathological and neuroimaging study of a case. J Neurosurg Sci. 2000;44(4):234–7.PubMed
10.
11.
12.
Saito H, Ogasawara K, Beppu T, et al. Biological characteristics of a cerebellar mass regrowing after removal in a patient with Lhermitte-Duclos disease: emission tomography studies. Case Rep Neurol. 2014;6(1):96–100.CrossRefPubMedPubMedCentral
13.
Jain N, Chauhan U, Goel V, et al. Lhermitte-Duclos disease: diagnosis on MRI, MR spectroscopy, CT and positron emission tomography. J Clin Diagn Res. 2015;9(9):TJ01–2.PubMedPubMedCentral
14.
Ashley DG, Zee CS, Chandrasoma PT, et al. Lhermitte-Duclos disease: CT and MR findings. J Comput Assist Tomogr. 1990;14(6):984–7.CrossRefPubMed
15.
16.
Shimanskiy VN, Karnaukhov VV, Shishkina LV, et al. The successful treatment of a patient with Lhermitte-Duclos disease (A case report and literature review). Zh Vopr Neirokhir Im N N Burdenko. 2015;79(4):78.CrossRefPubMed
17.
Golden N, Tjokorda MG, Sri M, et al. Management of unusual dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease) in a developing country: case report and review of the literature. Asian J Neurosurg. 2016;11(2):170.PubMedPubMedCentral
18.
Matsumoto H, Minami H, Yoshida Y. Lhermitte-Duclos disease treated surgically in an elderly patient: case report and literature review. Turk Neurosurg. 2015;25(5):783–7.PubMed
Metadata
Title
A case report of Lhermitte–Duclos disease revealed by psychiatric disturbances
Authors
Yassine Otheman
Rachid Aalouane
Chadia Aarab
Ismail Rammouz
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2017
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/s12991-017-0147-1

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