Skip to main content
Top
Published in: BMC Anesthesiology 1/2015

Open Access 01-12-2015 | Case report

A case of asystole from carotid sinus hypersensitivity during patient positioning for thyroidectomy

Authors: Emmanuel Lilitsis, Alexia Papaioannou, Aikaterini Hatzimichali, Konstantinos Spyridakis, Sofia Xenaki, George Chalkiadakis, Emmanuel Chrysos

Published in: BMC Anesthesiology | Issue 1/2015

Login to get access

Abstract

Background

We present a case of a patient with multinodular goiter disease who suffered asystole during head hyperextension for surgical positioning on the operational table.

Case Presentation

Manipulation of carotid sinus may trigger bradycardia or even asystole even in patients without prior history of carotid sinus hypersensitivity. The time proximity between patient positioning and asystole, the late responsiveness to atropine, the immediate increase of heart rate after head elevation and the lack of any other trigger factor or prior history support the hypothesis of carotid sinus syndrome.

Conclusions

Head hyperextension during surgical positioning is not only responsible for jeopardizing blood flow to spinal cord and brainstem but may trigger reflexes, as well, even in patients without prior neck pathology.
Literature
1.
go back to reference Knight DJW, Mahajan RP. Patient positioning in anaesthesia continuing education in anaesthesia. Critical Care & Pain. 2004;4(5):160–63. Knight DJW, Mahajan RP. Patient positioning in anaesthesia continuing education in anaesthesia. Critical Care & Pain. 2004;4(5):160–63.
3.
go back to reference Bacuzzi A, Dionigi G, Del Bosco A, Cantone G, Sansone T, Di Losa E, Cuffari S. Anaesthesia for thyroid surgery: perioperative management. Int J Surg. 2008;6:S82–5.CrossRefPubMed Bacuzzi A, Dionigi G, Del Bosco A, Cantone G, Sansone T, Di Losa E, Cuffari S. Anaesthesia for thyroid surgery: perioperative management. Int J Surg. 2008;6:S82–5.CrossRefPubMed
4.
go back to reference Mercieri M, Paolini S, Mercieri A, De Blasi RA, Palmisani S, Pinto G, Arcioni R. Tetraplegia following parathyroidectomy in two long-term haemodialysis patients. Anaesthesia. 2009;64:1010–3.CrossRefPubMed Mercieri M, Paolini S, Mercieri A, De Blasi RA, Palmisani S, Pinto G, Arcioni R. Tetraplegia following parathyroidectomy in two long-term haemodialysis patients. Anaesthesia. 2009;64:1010–3.CrossRefPubMed
5.
go back to reference Sear JW, Foex P. Recommendations on perioperative b-blockers: differing guidelines: so what should the clinician do? British J Anaesthesia. 2010;104(3): 273–5. Sear JW, Foex P. Recommendations on perioperative b-blockers: differing guidelines: so what should the clinician do? British J Anaesthesia. 2010;104(3): 273–5.
6.
go back to reference Fleischmann KE, Beckman JA, Buller CE, Calkins H, Fleisher LA, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Robb JF, Valentine RJ. 2009 ACCF/AHA focused update on perioperative beta blockade. Circulation. 2009;120:2123–51.CrossRefPubMed Fleischmann KE, Beckman JA, Buller CE, Calkins H, Fleisher LA, Freeman WK, Froehlich JB, Kasper EK, Kersten JR, Robb JF, Valentine RJ. 2009 ACCF/AHA focused update on perioperative beta blockade. Circulation. 2009;120:2123–51.CrossRefPubMed
7.
go back to reference Parisha B, Hossam EM, Abida K, Emad K, Rohan RW. Remote access thyroid surgery. Gland Surg. 2015;4(5):376–87. Parisha B, Hossam EM, Abida K, Emad K, Rohan RW. Remote access thyroid surgery. Gland Surg. 2015;4(5):376–87.
9.
go back to reference Amin V, Pavri BB. Carotid sinus syndrome. Cardiol Rev. 2015;23:130–4.PubMed Amin V, Pavri BB. Carotid sinus syndrome. Cardiol Rev. 2015;23:130–4.PubMed
10.
go back to reference Developed in collaboration with, European Heart Rhythm Association (EHRA)1, Heart Failure Association (HFA)2, and Heart Rhythm Society (HRS)3. Guidelines for the diagnosis and management of syncope (version 2009). Eur Heart J. 2009;30:2631–671. Developed in collaboration with, European Heart Rhythm Association (EHRA)1, Heart Failure Association (HFA)2, and Heart Rhythm Society (HRS)3. Guidelines for the diagnosis and management of syncope (version 2009). Eur Heart J. 2009;30:2631–671.
11.
go back to reference Sachpekidis V, Vogiatzis I, Dadous G, Kanonidis I, Papadopoulos C, Sakadamis G. Carotid sinus hypersensitivity is common in patients pre- senting with hip fracture and unexplained falls. Pacing Clin Electrophysiol. 2009;32:1184–90.CrossRefPubMed Sachpekidis V, Vogiatzis I, Dadous G, Kanonidis I, Papadopoulos C, Sakadamis G. Carotid sinus hypersensitivity is common in patients pre- senting with hip fracture and unexplained falls. Pacing Clin Electrophysiol. 2009;32:1184–90.CrossRefPubMed
12.
go back to reference Tea SH, Mansourati J, L’Heveder G, Mabin D, Blanc J-J. New insights into the pathophysiology of carotid sinus syndrome. Circulation. 1996;93:1411–6.CrossRefPubMed Tea SH, Mansourati J, L’Heveder G, Mabin D, Blanc J-J. New insights into the pathophysiology of carotid sinus syndrome. Circulation. 1996;93:1411–6.CrossRefPubMed
13.
go back to reference Blanc J-J, L’Heveder G, Mansourati J, Tea SH, Guillo P, Mabin D. Assessment of a newly recognized association: carotid sinus hypersensitivity and denervation of the sternocleidomastoid muscles. Circulation. 1997;95:2548–51.CrossRefPubMed Blanc J-J, L’Heveder G, Mansourati J, Tea SH, Guillo P, Mabin D. Assessment of a newly recognized association: carotid sinus hypersensitivity and denervation of the sternocleidomastoid muscles. Circulation. 1997;95:2548–51.CrossRefPubMed
14.
go back to reference Amin V, Pavri BB. Carotid sinus syndrome. cardiology in review. 2015;23(3):1–8. Amin V, Pavri BB. Carotid sinus syndrome. cardiology in review. 2015;23(3):1–8.
15.
go back to reference O’Mahony D. Pathophysiology of carotid sinus hypersensitivity in elderly patients. Lancet. 1995;346:950–2.CrossRefPubMed O’Mahony D. Pathophysiology of carotid sinus hypersensitivity in elderly patients. Lancet. 1995;346:950–2.CrossRefPubMed
16.
go back to reference Lacerda GDC, Pedrosa RC, Lacerda RCD, Santos MCD, Perez MDA, Teixeira AB, Siqueira-Filho AGD. Cardioinhibitory carotid sinus hypersensitivity: prevalence and predictors in 502 outpatients. Arq Bras Cardiol. 2008;90(3):148–55.CrossRefPubMed Lacerda GDC, Pedrosa RC, Lacerda RCD, Santos MCD, Perez MDA, Teixeira AB, Siqueira-Filho AGD. Cardioinhibitory carotid sinus hypersensitivity: prevalence and predictors in 502 outpatients. Arq Bras Cardiol. 2008;90(3):148–55.CrossRefPubMed
17.
go back to reference Griffioen KJ, Venkatesan P, Huang ZG, Wang X, Bouairi E, Evans C, Gold A, Mendelowitz D. Fentanyl inhibits GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Brain Res. 2004;1007(1–2):109–15.CrossRefPubMed Griffioen KJ, Venkatesan P, Huang ZG, Wang X, Bouairi E, Evans C, Gold A, Mendelowitz D. Fentanyl inhibits GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Brain Res. 2004;1007(1–2):109–15.CrossRefPubMed
18.
go back to reference Wang X, Huang ZG, Gold A, Bouairi E, Evans C, Andresen MC, Mendelowitz D. Propofol modulates gamma-aminobutyric acid-mediated inhibitory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Anesthesiology. 2004;100(5):1198–205.CrossRefPubMed Wang X, Huang ZG, Gold A, Bouairi E, Evans C, Andresen MC, Mendelowitz D. Propofol modulates gamma-aminobutyric acid-mediated inhibitory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Anesthesiology. 2004;100(5):1198–205.CrossRefPubMed
19.
go back to reference Wenger TL, et al. Hypersensitive carotid sinus syndrome manifested as cough syncope. Pacing Clin Electrophysiol. 1980;3:332–9.CrossRefPubMed Wenger TL, et al. Hypersensitive carotid sinus syndrome manifested as cough syncope. Pacing Clin Electrophysiol. 1980;3:332–9.CrossRefPubMed
20.
21.
go back to reference Wallin BG, et al. Syncope induced by glossopharyngeal neuralgia: sympathetic outflow to muscle. Neurology. 1984;34:522–4.CrossRefPubMed Wallin BG, et al. Syncope induced by glossopharyngeal neuralgia: sympathetic outflow to muscle. Neurology. 1984;34:522–4.CrossRefPubMed
22.
go back to reference Tulchinsky M, et al. Carotid sinus syndrome associated with an occult primary nasopharyngeal carcinoma. Arch Intern Med. 1988;148:1217–9.CrossRefPubMed Tulchinsky M, et al. Carotid sinus syndrome associated with an occult primary nasopharyngeal carcinoma. Arch Intern Med. 1988;148:1217–9.CrossRefPubMed
23.
go back to reference Mehta, et al. Carotid sinus syndrome as a manifestation of head and neck cancer–case report and literature review. Int J Clin Cardiol. 2014;1:2.CrossRef Mehta, et al. Carotid sinus syndrome as a manifestation of head and neck cancer–case report and literature review. Int J Clin Cardiol. 2014;1:2.CrossRef
24.
go back to reference Fourquet N, Genet L, Davy-Chedaute F. Carotid sinus hypersensitivity associated with a treated otorhinolaryngologic cancer. Study of 103 patients. Presse Med. 1991;20:1713–6.PubMed Fourquet N, Genet L, Davy-Chedaute F. Carotid sinus hypersensitivity associated with a treated otorhinolaryngologic cancer. Study of 103 patients. Presse Med. 1991;20:1713–6.PubMed
25.
go back to reference Sorgente A, Sarkozy A, Chierchia GB, de Asmundis C, Capulzini L, Brugada P. Carotid sinus hypersensitivity following radiotherapy delivery in a patient with bilateral glomus tumour. J Cardiovasc Med (Hagerstown). 2011;12(9):675–7. Sorgente A, Sarkozy A, Chierchia GB, de Asmundis C, Capulzini L, Brugada P. Carotid sinus hypersensitivity following radiotherapy delivery in a patient with bilateral glomus tumour. J Cardiovasc Med (Hagerstown). 2011;12(9):675–7.
26.
go back to reference Truong AT1, Sturgis EM, Rozner MA, Truong DT. Recurrent episodes of asystole from carotid sinus hypersensitivity triggered by positioning for head and neck surgery. Head Neck. 2013;35(1):E28–30. Truong AT1, Sturgis EM, Rozner MA, Truong DT. Recurrent episodes of asystole from carotid sinus hypersensitivity triggered by positioning for head and neck surgery. Head Neck. 2013;35(1):E28–30.
Metadata
Title
A case of asystole from carotid sinus hypersensitivity during patient positioning for thyroidectomy
Authors
Emmanuel Lilitsis
Alexia Papaioannou
Aikaterini Hatzimichali
Konstantinos Spyridakis
Sofia Xenaki
George Chalkiadakis
Emmanuel Chrysos
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2015
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-016-0255-5

Other articles of this Issue 1/2015

BMC Anesthesiology 1/2015 Go to the issue