Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Diagnostic Pathology
Published in: Diagnostic Pathology 1/2012

Open Access 01-12-2012 | Case Report

A case of Arrhythmogenic right ventricular cardiomyopathy without arrhythmias

Authors: Jia Wei, Jiarong Tang, Liming Xia, Xinshan Chen, Dao Wen Wang

Published in: Diagnostic Pathology | Issue 1/2012

Login to get access

Abstract

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by recurrent coma, ventricular tachycardias and the replacement of the myocardium with fatty and fibrous tissue. We described a 42-year-old female patient without clinical arrhythmias which was diagnosed as ARVC by magnetic resonance imaging (MRI), but the transvenous endomyocardial biopsy was not specific. The patient received heart transplantation due to her refractory heart failure and the pathology of explanted heart demonstrated typical replacement of fatty and fibrous tissue and piles of infiltrated lymphocytes in myocardial tissue. It is concluded that ARVC might not have any arrhythmias and inflammatory process may be involved in the mechanism of ARVC.

Virtual slides

The virtual slide(s) for this article can be found here:http://​www.​diagnosticpathol​ogy.​diagnomx.​eu/​vs/​6573514507145351​
Appendix
Available only for authorised users
Literature
1.
2.
Dalal D, et al.: Arrhythmogenic right ventricular dysplasia: a United States experience. Circulation. 2005, 112 (25): 3823-3832. 10.1161/CIRCULATIONAHA.105.542266.CrossRefPubMed
3.
Gemayel C, Pelliccia A, Thompson PD: Arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol. 2001, 38 (7): 1773-1781. 10.1016/S0735-1097(01)01654-0.CrossRefPubMed
4.
Hulot JS, et al.: Natural history and risk stratification of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circulation. 2004, 110 (14): 1879-1884. 10.1161/01.CIR.0000143375.93288.82.CrossRefPubMed
5.
Thiene G, et al.: Right ventricular cardiomyopathy and sudden death in young people. N Engl J Med. 1988, 318 (3): 129-133. 10.1056/NEJM198801213180301.CrossRefPubMed
6.
McKenna WJ, et al.: Diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Task Force of the Working Group Myocardial and Pericardial Disease of the European Society of Cardiology and of the Scientific Council on Cardiomyopathies of the International Society and Federation of Cardiology. Br Heart J. 1994, 71 (3): 215-218. 10.1136/hrt.71.3.215.PubMedCentralCrossRefPubMed
7.
Azaouagh A, et al.: Arrhythmogenic right ventricular cardiomyopathy/dysplasia: a review and update. Clin Res Cardiol. 2011, 100 (5): 383-394. 10.1007/s00392-011-0295-2.CrossRefPubMed
8.
Murphy DT, et al.: Cardiac MRI in arrhythmogenic right ventricular cardiomyopathy. AJR Am J Roentgenol. 2010, 194 (4): W299-W306. 10.2214/AJR.09.3450.CrossRefPubMed
9.
Corrado D, Basso C, Thiene G: Arrhythmogenic right ventricular cardiomyopathy: diagnosis, prognosis, and treatment. Heart. 2000, 83 (5): 588-595. 10.1136/heart.83.5.588.PubMedCentralCrossRefPubMed
10.
Angelini A, et al.: Endomyocardial biopsy in right ventricular cardiomyopathy. Int J Cardiol. 1993, 40 (3): 273-282. 10.1016/0167-5273(93)90011-5.CrossRefPubMed
11.
Cooper LT: Right from the heart: when should myocardial biopsy be performed for suspected arrhythmogenic right ventricular cardiomyopathy/dysplasia?. Eur Heart J. 2008, 29 (22): 2705-2707. 10.1093/eurheartj/ehn471.CrossRefPubMed
12.
Xiaojing H, Jiannong Z, Weibo X: The utility of magnetic resonance imaging in the evaluation of arrhythmogenic right ventricular cardiomyopathy. J Radiol. 2009, 90 (6): 717-723. 10.1016/S0221-0363(09)74726-2.CrossRefPubMed
13.
Chengwei L, et al.: Diagnosis of typical and early arrhythmogenic right ventricular cardiomyopathy by novel magnetic resonance imaging. Chin J Cardiol (Chin). 2002, 30: 661-665.
14.
Liu C, et al.: The diagnostic value of magnetic resonance imaging in arrhythmogenic right ventricular cardiomyopathy. Chin J Intern Med(Chin). 2002, 41: 191-193.
15.
Bowles NE, et al.: The detection of cardiotropic viruses in the myocardium of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Am Coll Cardiol. 2002, 39 (5): 892-895. 10.1016/S0735-1097(02)01688-1.CrossRefPubMed
16.
Thiene G, Basso C: Arrhythmogenic right ventricular cardiomyopathy: An update. Cardiovasc Pathol. 2001, 10 (3): 109-117. 10.1016/S1054-8807(01)00067-9.CrossRefPubMed
17.
Tavora F, et al.: Distribution of biventricular disease in arrhythmogenic cardiomyopathy: an autopsy study. Hum Pathol. 2012, 43 (4): 592-596. 10.1016/j.humpath.2011.06.014.CrossRefPubMed
18.
Corrado D, et al.: Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/dysplasia: a multicenter study. J Am Coll Cardiol. 1997, 30 (6): 1512-1520. 10.1016/S0735-1097(97)00332-X.CrossRefPubMed
19.
Gilljam T, Bergh CH: Right ventricular cardiomyopathy: timing of heart transplantation in Uhl's anomaly and arrythmogenic right ventricular cardiomyopathy. Eur J Heart Fail. 2009, 11 (1): 106-109. 10.1093/eurjhf/hfn014.CrossRefPubMed
20.
Yoda M, et al.: Three cases of orthotopic heart transplantation for arrhythmogenic right ventricular cardiomyopathy. Ann Thorac Surg. 2005, 80 (6): 2358-2360. 10.1016/j.athoracsur.2004.07.071.CrossRefPubMed
Metadata
Title
A case of Arrhythmogenic right ventricular cardiomyopathy without arrhythmias
Authors
Jia Wei
Jiarong Tang
Liming Xia
Xinshan Chen
Dao Wen Wang
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2012
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-7-67

Other articles of this Issue 1/2012

Diagnostic Pathology 1/2012 Go to the issue

Research

The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody

Research

Hsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease

Hypothesis

Introduction of virtual microscopy in routine surgical pathology - a hypothesis and personal view from Europe

Research

Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience

Research

Increased numbers of P63-positive/CD117-positive cells in advanced adenoid cystic carcinoma give a poorer prognosis

Case Report

Ileocolic intussusception due to a cecal endometriosis: Case report and review of literature