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Clinical Oral Investigations

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01-07-2015 | Original Article

A case-control study on oral health-related quality of life in kidney disease patients undergoing haemodialysis

Authors: Amir H. Pakpour, Santhosh Kumar, Bengt Fridlund, Stefan Zimmer

Published in: Clinical Oral Investigations | Issue 6/2015

Abstract

Objective

The study aims to assess the influence of oral health status and socio-behavioural variables on oral health-related quality of life (OHRQoL) in a sample of Iranian haemodialysis (HD) patients.

Materials and methods

The present case-control study included 512 patients undergoing HD and 255 healthy controls from Iran. A self-reported questionnaire was used to record socio-demographic variables. In addition, laboratory and clinical variables of each patient were extracted from clinical and patient’s electronic records. A closed-ended questionnaire was framed in order to assess oral health knowledge, attitudes and behaviour of each subject. The Short Form Health Survey (SF-36) and Oral Health Impact Profile-14 (OHIP-14) were used respectively to assess general health-related quality of life (GHRQoL) and OHRQoL. All subjects were clinically examined by two trained and experienced dentists for caries by decayed, missing and filled teeth index (DMFT), dental plaque by visible plaque index (VPI), gingival status by Loe and Silness gingival index (GI) and periodontal status by community periodontal index (CPI).

Results

Statistically significant differences were found between HD patients and control subjects for all oral health indices. Patients had significantly (p < 0.001) higher mean DMFT, VPI and GI values than controls. Periodontal pockets deeper than 4 mm were more frequently diagnosed in HD patients (p < 0.001). HD patients reported significantly poorer GHRQoL and also a higher impact of oral health (i.e. poorer OHRQoL) in comparison with the healthy controls (p < 0.01).

Conclusions

Oral health status, clinical variables, socio-behavioural factors and GHRQoL were significant predictors of OHRQoL in Iranian HD patients.

Clinical relevance

The study findings support the assumption that patient-reported measures can be used to predict treatment need since the objective clinical variables were significantly related to subjective self-reported quality of life in HD patients.

Aghighi M, Heidary Rouchi A, Zamyadi M, Mahdavi-Mazdeh M, Rajolani H, Ahrabi S, Zamani M (2008) Dialysis in Iran. Iran J Kidney Dis 2(1):11–15PubMed

Najafi I, Shakeri R, Islami F, Malekzadeh F, Salahi R, Yapan-Gharavi M, Hosseini M, Hakemi M, Alatab S, Rahmati A, Broumand B, Nobakht-Haghighi A, Larijani B, Malekzadeh R (2012) Prevalence of chronic kidney disease and its associated risk factors: the first report from Iran using both microalbuminuria and urine sediment. Arch Iran Med 15(2):70–75PubMed

Hamissi J, Porsamimi J, Naseh MR, Mosalaei S (2009) Oral hygiene and periodontal status of hemodialyzed patients with chronic renal failure in Qazvin, Iran. East Afr J Public Health 6(1):108–111PubMed

Feroze U, Noori N, Kovesdy CP, Molnar MZ, Martin DJ, Reina-Patton A, Benner D, Bross R, Norris KC, Kopple JD, Kalantar-Zadeh K (2011) Quality-of-life and mortality in hemodialysis patients: roles of race and nutritional status. Clin J Am Soc Nephrol 6(5):1100–1111PubMedCentralPubMedCrossRef

Pagels AA, Soderkvist BK, Medin C, Hylander B, Heiwe S (2012) Health-related quality of life in different stages of chronic kidney disease and at initiation of dialysis treatment. Health Qual Life Outcomes 10:71PubMedCentralPubMedCrossRef

Akar H, Akar GC, Carrero JJ, Stenvinkel P, Lindholm B (2011) Systemic consequences of poor oral health in chronic kidney disease patients. Clin J Am Soc Nephrol 6(1):218–226PubMedCrossRef

Chen LP, Chiang CK, Chan CP, Hung KY, Huang CS (2006) Does periodontitis reflect inflammation and malnutrition status in hemodialysis patients? Am J Kidney Dis 47:815–822PubMedCrossRef

Guzeldemir E, Toygar HU, Tasdelen B, Torun D (2009) Oral health-related quality of life and periodontal health status in patients undergoing hemodialysis. J Am Dent Assoc 140(10):1283–1293PubMedCrossRef

Locker D, Matear D, Stephens M, Jokovic A (2002) Oral health-related quality of life of a population of medically compromised elderly people. Commun Dent Health 19(2):90–97

10.

Jensen PM, Saunders RL, Thierer T, Friedman B (2008) Factors associated with oral health-related quality of life in community-dwelling elderly persons with disabilities. J Am Geriatr Soc 56(4):711–717PubMedCrossRef

11.

Li Z, Zhu L, Sha Y (2011) Effects of periodontal health and related factors on the oral health-related quality of life in type 2 diabetic patients with chronic periodontitis. Hua xi kou Qiang yi xue za zhi 29(4):379–383PubMed

12.

Dental Statistics and Research Unit (2003) Social determinants of oral health. Australian Institute of Health and Welfare, Adelaide

13.

Ware JJ, Gandek B (1998) Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) project. J Clin Epidemiol 51(11):903–912PubMedCrossRef

14.

Montazeri A, Goshtasebi A, Vahdaninia M, Gandek B (2005) The Short Form Health Survey (SF-36): translation and validation study of the Iranian version. Qual Life Res 14(3):875–882PubMedCrossRef

15.

Pakpour AH, Nourozi S, Molsted S, Harrison AP, Nourozi K, Fridlund B (2011) Validity and reliability of short form-12 questionnaire in Iranian hemodialysis patients. Iran J Kidney Dis 5(3):175–181PubMed

16.

Pakpour AH, Saffari M, Yekaninejad MS, Panahi D, Harrison AP, Molsted S (2010) Health-related quality of life in a sample of Iranian patients on hemodialysis. Iran J Kidney Dis 4(1):50–59PubMed

17.

Slade GD (1997) Derivation and validation of a short-form oral health impact profile. Commun Dent Oral Epidemiol 25(4):284–290CrossRef

18.

Ravaghi V, Farrahi-Avval N, Locker D, Underwood M (2010) Validation of the Persian short version of the Oral Health Impact Profile (OHIP-14). Oral Health Prev Dent 8(3):229–235PubMed

19.

World Health Organization (1997) Oral health surveys, basic methods. 4th edn. World Health Organization: Oral Health Unit, Geneva

20.

Loe H, Silness J (1963) Periodontal disease in pregnancy I. Prevalence and severity. Acta Odontol Scand 21:533–551PubMedCrossRef

21.

Turesky S, Gilmore N, Glickman I (1970) Reduced plaque formation by the chloromethyl analogue of victamine C. J Periodontol 41(1):41–43PubMedCrossRef

22.

Ziebolz D, Fischer P, Hornecker E, Mausberg RF (2012) Oral health of hemodialysis patients: a cross-sectional study at two German dialysis centers. Hemodial Int 16(1):69–75PubMed

23.

Bots CP, Poorterman JH, Brand HS, Kalsbeek H, van Amerongen BM, Veerman EC, Nieuw Amerongen AV (2006) The oral health status of dentate patients with chronic renal failure undergoing dialysis therapy. Oral Dis 12(2):176–180PubMedCrossRef

24.

Bayraktar G, Kurtulus I, Duraduryan A, Cintan S, Kazancioglu R, Yildiz A, Bural C, Bozfakioglu S, Besler M, Trablus S, Issever H (2007) Dental and periodontal findings in hemodialysis patients. Oral Dis 13(4):393–397PubMedCrossRef

25.

Ahluwalia KP, Cheng B, Josephs PK, Lalla E, Lamster IB (2010) Oral disease experience of older adults seeking oral health services. Gerodontology 27(2):96–103PubMedCrossRef

26.

Kotzer RD, Lawrence HP, Clovis JB, Matthews DC (2012) Oral health-related quality of life in an aging Canadian population. Health Qual Life Outcomes 10:50PubMedCentralPubMedCrossRef

27.

Borawski J, Wilczynska-Borawska M, Stokowska W, Mysliwiec M (2007) The periodontal status of pre-dialysis chronic kidney disease and maintenance dialysis patients. Nephrol Dial Transplant 22(2):457–464PubMedCrossRef

28.

Germin-Petrovic D, Mesaros-Devcic I, Lesac A, Mandic M, Soldatic M, Vezmar D, Petric D, Vujicic B, Basic-Jukic N, Racki S (2011) Health-related quality of life in the patients on maintenance hemodialysis: the analysis of demographic and clinical factors. Coll Antropol 35(3):687–693PubMed

29.

Depasquale C, Pistorio ML, Corona D, Mistretta A, Zerbo D, Sinagra N, Giaquinta A, Tallarita T, Esker B, Mociskyte D, Leonardi A, Gula R, Veroux P, Veroux M (2012) Correlational study between psychic symptoms and quality of life among hemodialysis patients older than 55 years of age. Transplant Proc 44:1876–1878PubMedCrossRef

30.

Zimmer S, Bergmann N, Gabrun E, Barthel C, Raab W, Rüffer JU (2010) Association between oral health-related and general health-related quality of life in subjects attending dental offices in Germany. J Publ Health Dent 70:167–170

31.

Edelstein BL (2002) Disparities in oral health and access to care: findings of national surveys. Ambul Pediatr 2(2 Suppl):141–147PubMedCrossRef

32.

Gilbert GH, Duncan RP, Shelton BJ (2003) Social determinants of tooth loss. Health Serv Res 38(6 Pt 2):1843–1862PubMedCentralPubMedCrossRef

33.

World Health Survey 2003 results (2007) World Health Organization. http://ww.who.int/healthinfo/survey/whsresults/en/index/html. Accessed 2013

34.

Bayat F, Murtomaa H, Vehkalahti MM, Tala H (2011) Eur J Dent 5:68–76PubMedCentralPubMed

35.

Vazquez I, Valderrabano F, Fort J, Jofre R, Lopez-Gomez JM, Moreno F, Sanz-Guajardo D (2005) Psychosocial factors and health-related quality of life in hemodialysis patients. Qual Life Res 14(1):179–190PubMedCrossRef

36.

Barbosa TS, Gaviao MB (2008) Oral health-related quality of life in children: part II. Effects of clinical oral health status: a systematic review. Int J Dent Hyg 6(2):100–107PubMedCrossRef

37.

Shanbhag SDM, Croucher R (2012) The impact of periodontal therapy on oral health-related quality of life in adults: a systematic review. J Clin Periodontol 39:725–735PubMedCrossRef

38.

Williams SD, Parker ED, Jamieson LM (2010) Oral health-related quality of life among rural-dwelling indigenous Australians. Aust Dent J 55:170–176PubMedCrossRef

39.

Maida CA, Marcus M, Spolsky VW, Wang Y, Liu H (2013) Socio-behavioral predictors of self-reported oral health-related quality of life. Qual Life Res 22(3):559–566PubMedCrossRef

Title: A case-control study on oral health-related quality of life in kidney disease patients undergoing haemodialysis
Authors: Amir H. Pakpour
Santhosh Kumar
Bengt Fridlund
Stefan Zimmer
Publication date: 01-07-2015
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 6/2015
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-014-1355-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A case-control study on oral health-related quality of life in kidney disease patients undergoing haemodialysis

Abstract

Objective

Materials and methods

Results

Conclusions

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Materials and methods

Results

Conclusions

Clinical relevance

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