Published in:
Open Access
01-12-2015 | Poster presentation
A better way to determine sample size to detect changes in length of mechanical ventilation?
Authors:
YS Chiew, C Pretty, D Redmond, GM Shaw, T Desaive, JG Chase
Published in:
Critical Care
|
Special Issue 1/2015
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Excerpt
Estimation of effective sample size (N/arm) is important to ensure power to detect significant treatment effects. However, traditional parametric sample size estimations depend upon restrictive assumptions that often do not hold in real data. This study estimates N to detect changes in length of mechanical ventilation (LoMV) using Monte-Carlo simulation (MCS) and mechanical ventilation (MV) data to better simulate the cohort. …