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01-12-2004 | Original Article

A 12-month clinical survey of incidence and outcome of acute respiratory distress syndrome in Shanghai intensive care units

Authors: Yueming Lu, Zhifang Song, Xin Zhou, Shaoguang Huang, Duming Zhu, Xingyi Yang C. Bai, Bo Sun, Roger Spragg, Shanghai ARDS Study Group

Published in: Intensive Care Medicine | Issue 12/2004

Abstract

Objective

To investigate incidence, causes, and outcome of acute respiratory distress syndrome (ARDS) in adult patients admitted to intensive care units (ICU) in Shanghai.

Design

A prospective 12-month survey during 2001–2002 of the predispositions, clinical management strategies, complications, and 90-day survival rates of patients with ARDS.

Patients and setting

Fifteen ICU in 12 university hospitals in Shanghai. All ICU admissions ≥15 years of age in the 12-month period were assessed. Patients fulfilling diagnostic criteria of ARDS, as defined by the American–European Consensus Conference, and having a continuous treatment period ≥24 h, were recruited.

Measurements and results

Of 5320 adult patients admitted to ICUs, there were 108 (2%) with ARDS. At inclusion, ARDS patients had a mean PaO₂/FiO₂ value of 111.3±40.3 mmHg and a mean acute physiology and chronic health evaluation score (APACHE II) of 17.3±8.0; 33 patients had a lung injury score >2.5. Forty-one and 67 patients had ARDS associated with diseases of pulmonary and extrapulmonary origin, respectively. The most common predisposing factors for ARDS were pneumonia (34.3%) and nonpulmonary sepsis (30.6%). The overall ICU mortality was 10.3%. In-hospital and 90-day mortalities of ARDS patients were 68.5 and 70.4%, respectively, and accounted for 13.5% of the overall ICU mortality. For ARDS patients, multiple organ dysfunction syndrome was a major risk factor associated with death (59.5%).

Conclusion

The high morbidity and mortality of ARDS in the ICUs in Shanghai require reassessment of respiratory and intensive care management and implementation of effective therapeutic interventions.

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Title: A 12-month clinical survey of incidence and outcome of acute respiratory distress syndrome in Shanghai intensive care units
Authors: Yueming Lu
Zhifang Song
Xin Zhou
Shaoguang Huang
Duming Zhu
Xingyi Yang C. Bai
Bo Sun
Roger Spragg
Shanghai ARDS Study Group
Publication date: 01-12-2004
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 12/2004
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-004-2479-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A 12-month clinical survey of incidence and outcome of acute respiratory distress syndrome in Shanghai intensive care units

Abstract

Objective

Design

Patients and setting

Measurements and results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Design

Patients and setting

Measurements and results

Conclusion

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