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Nuclear Medicine and Molecular Imaging
Published in: Nuclear Medicine and Molecular Imaging 4/2016

01-12-2016 | Interesting Image

(99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia

Authors: Gaetano Paone, Luca Mazzucchelli, Giuseppe Peloni, Fabrizio Fasolini, Luca Giovanella

Published in: Nuclear Medicine and Molecular Imaging | Issue 4/2016

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Abstract

A 71-year-old female underwent a (99m)Tc-MIBI scan to characterize a cold nodule (30 mm) of the left thyroid lobe. The nodule showed diffuse uptake and retention of the radiotracer. After resection, histological examination demonstrated a microfollicular adenoma with diffuse white adipose metaplasia. Although mitochondria in brown adipose tissue have been widely studied, we have only a limited understanding of the relevance of mitochondria in white adipose tissue. Active mitochondria are present in white adipocytes, and this may account for the MIBI uptake, mimicking a hyperproliferation pattern, in our patient.
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Metadata
Title
(99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia
Authors
Gaetano Paone
Luca Mazzucchelli
Giuseppe Peloni
Fabrizio Fasolini
Luca Giovanella
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
Nuclear Medicine and Molecular Imaging / Issue 4/2016
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-015-0383-8

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