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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2015 | Review

4D flow cardiovascular magnetic resonance consensus statement

Authors: Petter Dyverfeldt, Malenka Bissell, Alex J. Barker, Ann F. Bolger, Carl-Johan Carlhäll, Tino Ebbers, Christopher J. Francios, Alex Frydrychowicz, Julia Geiger, Daniel Giese, Michael D. Hope, Philip J. Kilner, Sebastian Kozerke, Saul Myerson, Stefan Neubauer, Oliver Wieben, Michael Markl

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2015

Abstract

Pulsatile blood flow through the cavities of the heart and great vessels is time-varying and multidirectional. Access to all regions, phases and directions of cardiovascular flows has formerly been limited. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has enabled more comprehensive access to such flows, with typical spatial resolution of 1.5×1.5×1.5 – 3×3×3 mm³, typical temporal resolution of 30–40 ms, and acquisition times in the order of 5 to 25 min. This consensus paper is the work of physicists, physicians and biomedical engineers, active in the development and implementation of 4D Flow CMR, who have repeatedly met to share experience and ideas. The paper aims to assist understanding of acquisition and analysis methods, and their potential clinical applications with a focus on the heart and greater vessels. We describe that 4D Flow CMR can be clinically advantageous because placement of a single acquisition volume is straightforward and enables flow through any plane across it to be calculated retrospectively and with good accuracy. We also specify research and development goals that have yet to be satisfactorily achieved. Derived flow parameters, generally needing further development or validation for clinical use, include measurements of wall shear stress, pressure difference, turbulent kinetic energy, and intracardiac flow components. The dependence of measurement accuracy on acquisition parameters is considered, as are the uses of different visualization strategies for appropriate representation of time-varying multidirectional flow fields. Finally, we offer suggestions for more consistent, user-friendly implementation of 4D Flow CMR acquisition and data handling with a view to multicenter studies and more widespread adoption of the approach in routine clinical investigations.

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Title: 4D flow cardiovascular magnetic resonance consensus statement
Authors: Petter Dyverfeldt
Malenka Bissell
Alex J. Barker
Ann F. Bolger
Carl-Johan Carlhäll
Tino Ebbers
Christopher J. Francios
Alex Frydrychowicz
Julia Geiger
Daniel Giese
Michael D. Hope
Philip J. Kilner
Sebastian Kozerke
Saul Myerson
Stefan Neubauer
Oliver Wieben
Michael Markl
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue 1/2015
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/s12968-015-0174-5

At a glance: The STEP trials

Springer Medicine

4D flow cardiovascular magnetic resonance consensus statement

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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