Skip to main content
Top
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 2/2016

01-02-2016 | Retinal Disorders

25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane for the repair of giant retinal tears

Authors: John C. Randolph, Rocio I. Diaz, Eric J. Sigler, Jorge I. Calzada, Steve Charles

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2016

Login to get access

Abstract

Purpose

The purpose of this study was to describe the treatment of giant retinal tears (GRTs) with 25-gauge pars plana vitrectomy (PPV) and medium-term postoperative perfluoro-n-octane (MT-PFO).

Methods

The study was a retrospective interventional case series of consecutive patients with GRTs treated with 25-gauge PPV and postoperative MT-PFO for a period of 2–3 weeks. A second, staged procedure was performed in all patients for PFO removal.

Results

Twenty-three eyes of 22 patients were studied, with a mean follow-up of 33.04 ± 19.74 months. Successful reattachment was achieved in 91.3 % of eyes (21/23) after MT-PFO. Retinal re-detachment occurred in five eyes, which was caused by proliferative vitreoretinopathy. Additional complications included cataract progression (n = 10), foreign body response (30.4 %, 7/23), and transient intraocular pressure (IOP) elevation (8/23, 34.8 %). Transient IOP elevation was associated with worse visual outcome (p = 0.01).

Conclusions

MT-PFO was found to be an effective and safe technique for operative management of GRTs. In the majority of patients, retinas remained attached without further surgical intervention. Cataract progression, intraocular inflammation, and associated increased intraocular pressure are potential complications of MT-PFO.
Literature
1.
go back to reference Girard P, Boscher C, Navarro F, Forest A (1984) Retinal detachments caused by giant tear. J Fr Ophtalmol 7(3):205–209PubMed Girard P, Boscher C, Navarro F, Forest A (1984) Retinal detachments caused by giant tear. J Fr Ophtalmol 7(3):205–209PubMed
2.
go back to reference Glaser BM (1986) Treatment of giant retinal tears combined with proliferative vitreoretinopathy. Ophthalmology 93(9):1193–1197PubMedCrossRef Glaser BM (1986) Treatment of giant retinal tears combined with proliferative vitreoretinopathy. Ophthalmology 93(9):1193–1197PubMedCrossRef
3.
go back to reference Scott IU, Murray TG, Flynn HW Jr, Feuer WJ, Schiffman JC, Perfluoron Study G (2002) Outcomes and complications associated with giant retinal tear management using perfluoro-n-octane. Ophthalmology 109(10):1828–1833PubMedCrossRef Scott IU, Murray TG, Flynn HW Jr, Feuer WJ, Schiffman JC, Perfluoron Study G (2002) Outcomes and complications associated with giant retinal tear management using perfluoro-n-octane. Ophthalmology 109(10):1828–1833PubMedCrossRef
4.
go back to reference Sigler EJ, Randolph JC, Calzada JI, Charles S (2013) 25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane tamponade for inferior retinal detachment. Ophthalmic Surg Lasers Imaging Retina 44(1):34–40. doi:10.3928/23258160-20121221-10 PubMedCrossRef Sigler EJ, Randolph JC, Calzada JI, Charles S (2013) 25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane tamponade for inferior retinal detachment. Ophthalmic Surg Lasers Imaging Retina 44(1):34–40. doi:10.​3928/​23258160-20121221-10 PubMedCrossRef
5.
go back to reference Sigler EJ, Randolph JC, Calzada JI, Charles S (2013) Pars plana vitrectomy with medium-term postoperative perfluoro-N-octane for recurrent inferior retinal detachment complicated by advanced proliferative vitreoretinopathy. Retina 33(4):791–797. doi:10.1097/IAE.0b013e31826a6978 PubMedCrossRef Sigler EJ, Randolph JC, Calzada JI, Charles S (2013) Pars plana vitrectomy with medium-term postoperative perfluoro-N-octane for recurrent inferior retinal detachment complicated by advanced proliferative vitreoretinopathy. Retina 33(4):791–797. doi:10.​1097/​IAE.​0b013e31826a6978​ PubMedCrossRef
6.
go back to reference Rofail M, Lee LR (2005) Perfluoro-n-octane as a postoperative vitreoretinal tamponade in the management of giant retinal tears. Retina 25(7):897–901PubMedCrossRef Rofail M, Lee LR (2005) Perfluoro-n-octane as a postoperative vitreoretinal tamponade in the management of giant retinal tears. Retina 25(7):897–901PubMedCrossRef
10.
go back to reference Charles S, Calzada J, Wood B (2011) General posterior segment techniques. In: Pine J (ed) Vitreous microsurgery, 5th edn. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, pp 58–64 Charles S, Calzada J, Wood B (2011) General posterior segment techniques. In: Pine J (ed) Vitreous microsurgery, 5th edn. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, pp 58–64
11.
go back to reference Charles S, Calzada J, Wood B (2011) Giant breaks. In: Pine J (ed) Vitreous microsurgery, 5th edn. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, pp 138–143 Charles S, Calzada J, Wood B (2011) Giant breaks. In: Pine J (ed) Vitreous microsurgery, 5th edn. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, pp 138–143
12.
14.
go back to reference The Retina Society Terminology Committee (1983) The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology 90(2):121–125 The Retina Society Terminology Committee (1983) The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology 90(2):121–125
15.
go back to reference Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 140(3):509–516PubMedCrossRef Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 140(3):509–516PubMedCrossRef
16.
go back to reference Chen CH, Tsai MH, Su CC, Kou HK, Kao ML, Tsai SH, Chen YJ (2001) Results of 12-year clinical study of giant retinal tear. Chang Gung Med J 24(10):633–639PubMed Chen CH, Tsai MH, Su CC, Kou HK, Kao ML, Tsai SH, Chen YJ (2001) Results of 12-year clinical study of giant retinal tear. Chang Gung Med J 24(10):633–639PubMed
17.
go back to reference Goezinne F, La Heij EC, Berendschot TT, Gast ST, Liem AT, Lundqvist IL, Hendrikse F (2008) Low redetachment rate due to encircling scleral buckle in giant retinal tears treated with vitrectomy and silicone oil. Retina 28(3):485–492. doi:10.1097/IAE.0b013e318150d879 PubMedCrossRef Goezinne F, La Heij EC, Berendschot TT, Gast ST, Liem AT, Lundqvist IL, Hendrikse F (2008) Low redetachment rate due to encircling scleral buckle in giant retinal tears treated with vitrectomy and silicone oil. Retina 28(3):485–492. doi:10.​1097/​IAE.​0b013e318150d879​ PubMedCrossRef
18.
go back to reference Leaver PK, Billington BM (1989) Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: 5 years follow-up. Graefes Arch Clin Exp Ophthalmol 227(4):323–327PubMedCrossRef Leaver PK, Billington BM (1989) Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: 5 years follow-up. Graefes Arch Clin Exp Ophthalmol 227(4):323–327PubMedCrossRef
19.
go back to reference Camacho H, Bajaire B, Mejia LF (1992) Silicone oil in the management of giant retinal tears. Ann Ophthalmol 24(2):45–49PubMed Camacho H, Bajaire B, Mejia LF (1992) Silicone oil in the management of giant retinal tears. Ann Ophthalmol 24(2):45–49PubMed
20.
go back to reference Karel I, Michalickova M, Soucek P (1996) Long-term results of pars plana vitrectomy and silicone oil for giant tears. Eur J Ophthalmol 6(3):315–321PubMed Karel I, Michalickova M, Soucek P (1996) Long-term results of pars plana vitrectomy and silicone oil for giant tears. Eur J Ophthalmol 6(3):315–321PubMed
21.
go back to reference Unlu N, Kocaoglan H, Acar MA, Sargin M, Aslan BS, Duman S (2003) The management of giant retinal tears with silicone oil. Eur J Ophthalmol 13(2):192–195PubMed Unlu N, Kocaoglan H, Acar MA, Sargin M, Aslan BS, Duman S (2003) The management of giant retinal tears with silicone oil. Eur J Ophthalmol 13(2):192–195PubMed
22.
go back to reference Hoffman ME, Sorr EM (1986) Management of giant retinal tears without scleral buckling. Retina 6(4):197–204PubMedCrossRef Hoffman ME, Sorr EM (1986) Management of giant retinal tears without scleral buckling. Retina 6(4):197–204PubMedCrossRef
23.
go back to reference Batman C, Cekic O (1999) Vitrectomy with silicone oil or long-acting gas in eyes with giant retinal tears: long-term follow-up of a randomized clinical trial. Retina 19(3):188–192PubMed Batman C, Cekic O (1999) Vitrectomy with silicone oil or long-acting gas in eyes with giant retinal tears: long-term follow-up of a randomized clinical trial. Retina 19(3):188–192PubMed
24.
go back to reference Al-Khairi AM, Al-Kahtani E, Kangave D, Abu El-Asrar AM (2008) Prognostic factors associated with outcomes after giant retinal tear management using perfluorocarbon liquids. Eur J Ophthalmol 18(2):270–277PubMed Al-Khairi AM, Al-Kahtani E, Kangave D, Abu El-Asrar AM (2008) Prognostic factors associated with outcomes after giant retinal tear management using perfluorocarbon liquids. Eur J Ophthalmol 18(2):270–277PubMed
26.
go back to reference Chang S, Sparrow JR, Iwamoto T, Gershbein A, Ross R, Ortiz R (1991) Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid. Retina 11(4):367–374PubMedCrossRef Chang S, Sparrow JR, Iwamoto T, Gershbein A, Ross R, Ortiz R (1991) Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid. Retina 11(4):367–374PubMedCrossRef
27.
go back to reference Elsing SH, Fekrat S, Green WR, Chang S, Wajer SD, Haller JA (2001) Clinicopathologic findings in eyes with retained perfluoro-n-octane liquid. Ophthalmology 108(1):45–48PubMedCrossRef Elsing SH, Fekrat S, Green WR, Chang S, Wajer SD, Haller JA (2001) Clinicopathologic findings in eyes with retained perfluoro-n-octane liquid. Ophthalmology 108(1):45–48PubMedCrossRef
28.
go back to reference Aylward GW, Cooling RJ, Leaver PK (1993) Trauma-induced retinal detachment associated with giant retinal tears. Retina 13(2):136–141PubMedCrossRef Aylward GW, Cooling RJ, Leaver PK (1993) Trauma-induced retinal detachment associated with giant retinal tears. Retina 13(2):136–141PubMedCrossRef
Metadata
Title
25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane for the repair of giant retinal tears
Authors
John C. Randolph
Rocio I. Diaz
Eric J. Sigler
Jorge I. Calzada
Steve Charles
Publication date
01-02-2016
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2016
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-015-3049-4

Other articles of this Issue 2/2016

Graefe's Archive for Clinical and Experimental Ophthalmology 2/2016 Go to the issue