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Open Access Sarcoma Case Study

Misdiagnosis of pulmonary artery sarcoma

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. But the case highlights some cardinal features of the malignancy that are not seen in vasculitis.

Pediatric hypertension doubles the risk for developing MACE

31-05-2024 Hypertension News

Children with hypertension are at an increased long-term risk for major adverse cardiac events compared with children without hypertension.

Digital interventions in hematologic malignancies

Free for a limited time Hematologic Cancer Review

Learn how digital technology via the use of web-based and smart device apps, remote monitoring devices, and patient portals, can improve the care of adult and pediatric patients with hematologic cancers.

BP management in intracerebral hemorrhage

Open Access Cerebral Hemorrhage Review

Hypertension is common in ICH, but inconsistent trial results have led to weak recommendations about acute blood pressure therapy. What target, timing, intensity, and agents should be used?

Polyvascular disease: a serious situation

Free for a limited time Arterial Diseases Review

Polyvascular disease (atherosclerosis in multiple vascular beds) has a high prevalence and elevated risk of mortality. Early identification and treatment are crucial to reduce disease progression. 

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Lung Cancer Clinical Trial Summary

At a glance: The KEYNOTE lung cancer trials

A quick guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in non-small-cell and small-cell lung cancer.

Developed by: Springer Medicine

Misdiagnosis of pulmonary artery sarcoma

Open Access Sarcoma Case Study

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. But the case highlights some cardinal features of the malignancy that are not seen in vasculitis.

DPP4 inhibitors a cause of IgG4-related kidney disease?

Free for a limited time Interstitial Nephritis Case Study

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.

Neonatal meningitis: new and old lessons

Open Access Meningitis in Childhood Case Study

A premature infant with extensive central nervous system injury from recurrent E. coli infection, requiring non-traditional methods to identify and clear the infection.

Live Webinar | 10-06-2024 | 16:30 (CEST)

Challenges in advanced CTCL – diagnosis and management

Live: Monday 10 June 2024, from 16:30 – 18:00 (CEST)

In this live interactive webinar, a multidisciplinary team of speakers will provide practical guidance on managing patients with cutaneous T-cell lymphoma. Learn about the key aspects of diagnosis and treatment via a series of patient cases.

Sponsored by: Kyowa Kirin

Developed by: Springer Healthcare

Current Reviews

Combination of spironolactone and DPP-4 inhibitors for treatment of SARS-CoV-2 infection: a literature review

Coronavirus disease 2019 (COVID-19) is still causing hospitalization and death, and vaccination appears to become less effective with each emerging variant. Spike, non-spike, and other possible unrecognized mutations have reduced the efficacy of …

Role of angiotensin II in cellular entry and replication of dengue virus

Previous studies have demonstrated the relevance of several soluble molecules in the pathogenesis of dengue. In this regard, a possible role for angiotensin II (Ang II) in the pathophysiology of dengue has been suggested by the observation of a …

Harnessing polyelectrolyte complexes for precision cancer targeting: a comprehensive review

Cancer Therapy Review Article

Polyelectrolytes represent a unique class of polymers abundant in ionizable functional groups. In a solution, ionized polyelectrolytes can intricately bond with oppositely charged counterparts, giving rise to a fascinating phenomenon known as a …

Complement and MHC patterns can provide the diagnostic framework for inflammatory neuromuscular diseases

Open Access Dermatomyositis Review

Histopathological analysis stands as the gold standard for the identification and differentiation of inflammatory neuromuscular diseases. These disorders continue to constitute a diagnostic challenge due to their clinical heterogeneity, rarity and …

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Springer Medicine webinars: on demand

Keynote webinar | Spotlight on sleep in brain health

Webinar | 02-05-2024 | 17:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Webinar | 19-02-2024 | 17:30 (CET)

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Keynote webinar | Spotlight on diet and diabetes

Webinar | 08-11-2023 | 18:00 (CET)

An expert-led symposium exploring the prevention and management of type 2 diabetes through dietary interventions. Highlights include discussion of the recent EASD guidelines, therapeutic diets, food types and processing, plus psychological factors that influence patient success, and the drivers of healthy eating and diabetes control.

Keynote webinar | Spotlight on cardio-oncology

Webinar | 16-05-2023 | 17:30 (CEST)

An expert-led symposium exploring the most pertinent issues in cardio-oncology, with a focus on the new ESC guidelines. Highlights include preventative approaches in cardio-oncology, toxicity risk-stratification strategies, the clinical management of myocarditis as an adverse effect of immune checkpoint inhibitor-treatments, and the utility of biomarkers in long-term follow-up of cardiovascular disease risk in cancer patients.

Webinar (Link opens in a new window)

1.25 AMA PRA Category 1 Credit(s)

A collaborative program highlighting the importance of molecular assessments and targeted treatment selection in people with biomarker-positive disease. Submit your questions for the experts now.

Supported by:
  • Roche and Illumina
Developed by: Springer Healthcare IME

Expert Interviews | Videos (Link opens in a new window)

With adolescent obesity at an all-time high, greater understanding of the individual cost and societal burden is crucial. Discover the unique challenges faced by adolescents with obesity, and learn effective strategies to help young people to overcome this disease.

This program is not available to users in the UK and US.

Supported by:
  • Novo Nordisk A/S
Developed by: Springer Healthcare IME

Tweetorials | Vodcasts | Infographics (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)

Stay up to date with the rapidly changing CGM landscape. Learn how to implement and integrate CGM into diabetes management to improve patient care and outcomes.

Supported by:
  • Abbott
Developed by: Springer Healthcare IME

Further Reading

CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease

Open Access Alzheimer's Disease Original Paper

Post-mortem staging of Alzheimer’s disease (AD) neurofibrillary pathology is commonly performed by immunohistochemistry using AT8 antibody for phosphorylated tau (p-tau) at positions 202/205. Thus, quantification of p-tau205 and p-tau202 in …

Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias

Open Access Alzheimer's Disease Original Paper

Reactive astrogliosis accompanies the two neuropathological hallmarks of Alzheimer’s disease (AD)—Aβ plaques and neurofibrillary tangles—and parallels neurodegeneration in AD and AD-related dementias (ADRD). Thus, there is growing interest in …

Factors associated with psychological distress during genetic counseling in high-risk women with breast cancer in Turkey

Open Access Breast Cancer Research

Detected most frequently in women and often resulting in death, breast cancer is a significant health issue around the world [ 1 , 2 ]. Each year, approximately 1 million women are diagnosed with breast cancer worldwide, with its incidence …

Optimal blood tau species for the detection of Alzheimer’s disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study

Open Access Alzheimer's Disease Original Paper

Plasma-to-autopsy studies are essential for validation of blood biomarkers and understanding their relation to Alzheimer’s disease (AD) pathology. Few such studies have been done on phosphorylated tau (p-tau) and those that exist have made limited …

Related topics

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. But the case highlights some cardinal features of the malignancy that are not seen in vasculitis.

Read more

Polyvascular disease (atherosclerosis in multiple vascular beds) has a high prevalence and elevated risk of mortality. Early identification and treatment are crucial to reduce disease progression. 

Read more

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.

Read more

A man with type 2 diabetes and IgG4-related kidney disease developed bullous pemphigoid. DPP4 inhibitor treatment, which also correlated with changes in renal function, was discontinued.

Read more

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. But the case highlights some cardinal features of the malignancy that are not seen in vasculitis.

Read more

A pulmonary arterial sarcoma was mistaken as pulmonary vasculitis due to similarities between the diagnoses. But the case highlights some cardinal features of the malignancy that are not seen in vasculitis.

Read more