Research Article | Volume: 7, Issue: 2, February, 2017

Hydroxycinnamic and organic acids of snowdrops (Galanthus L.)

Dmitry Olegovich Bokov ,  Aleksej Dmitrievich Malinkin,  Irina Aleksandrovna Samylina,  Vladimir Vladimirovich Bessonov   
Dmitry Olegovich Bokov1 & 2, Aleksej Dmitrievich Malinkin2, Irina Aleksandrovna Samylina1, Vladimir Vladimirovich Bessonov2

1I.M. Sechenov First Moscow State Medical University, 8, Trubetskaya st., Moscow, 119991, Russia.

2Federal research center of nutrition and biotechnology, 2/14, Ustyinsky pr., Moscow, 109240, Russia.

Open Access   

Published:  Feb 27, 2017

DOI: 10.7324/JAPS.2017.70205
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Abstract

The composition and content of hydroxycinnamic (HCA) and organic (OA) acids were investigated by HPLC with UV detection in Voronov’s snowdrop (Galanthus woronowii Losinsk.) and common snowdrop (Galanthus nivalis L.) crude herbal drugs. G. woronowii HCA composition is presented by neo chlorogenic, chlorogenic and cryptochlorogenic acids. Neo chlorogenic acid is absent in G. nivalis, but G. nivalis also contains chlorogenic and cryptochlorogenic acids. The total HCA content in G. woronowii was 84.1 ± 6.7 mg / 100 g, and in G. nivalis – 62.0 ± 5.0 mg / 100 g (0.06-0.08%). OA profile of two snowdrop species is presented by succinic, oxalic and malic acids. The total OA content in G. woronowii was 237.7 ± 2.4 mg / 100 g, and in G. nivalis – 405.1 ± 4.7 mg / 100 g (0.2-0.4%). The obtained data concerning minor specific biologically active substances composition can be used in the standardization and activity evaluation of drugs produced from snowdrops.


Keyword:     Hydroxycinnamic acids organic acids Galanthus woronowii Galanthus nivalis.

Citation:

Bokov DO, Malinkin AD, Samylina IA, Bessonov VV., Hydroxycinnamic and organic acids of snowdrops (Galanthus L.). J App Pharm Sci, 2017; 7 (02): 036-040.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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